JAVYGTOR

Product NDC
43598-096
11-digit product format
435980096
Labeler code
43598
Product ID
43598-096_ce2e0e3a-40e4-33ed-3cad-e166dd2245a1
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Sapropterin Dihydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Dr. Reddys Laboratories Inc
Application
ANDA207685
Marketing category
ANDA
Marketing start
2022-10-03
Substance
SAPROPTERIN DIHYDROCHLORIDE
Active strength
100 mg/1
Pharmacologic classes
Breast Cancer Resistance Protein Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA], Phenylalanine Hydroxylase Activator [EPC], Phenylalanine Hydroxylase Activators [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A207685-001SAPROPTERIN DIHYDROCHLORIDESAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A207685-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-158072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-155c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-155d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-154b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-156a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-151c564ffb4f44…
2023-12-20 04:57 UTC2023-12A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-159b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-153f0d92c62455…
2023-05-13 08:27 UTC2023-05A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15053a50430f4f…
2023-01-26 05:58 UTC2023-01A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-153bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-153a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A207685-001SAPROPTERIN DIHYDROCHLORIDE100MGTABLET / ORALAB2021-06-15a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A207685-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207685-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A207685-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207685-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207685-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207685-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207685-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207685-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207685-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207685-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207685-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207685-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207685-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207685-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207685-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207685-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207685-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A207685-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207685-001AB1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A207685-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A207685-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A207685-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A207685-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A207685-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A207685-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A207685-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A207685-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A207685-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A207685-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A207685-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A207685-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A207685-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A207685-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
JAVYGTOR
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SAPROPTERIN DIHYDROCHLORIDE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
RG277LF5B3Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1486687Internal RxNorm lookup
2612671Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
d9f3723f-bf7d-9a72-2ef9-41c5508d6ab4Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
8c453acf-b173-4ab3-9044-65304cdd78bfProduct name520260211

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
43598-096-04JAVYGTOR120 in 1 BOTTLETABLET1202
43598-096-05JAVYGTOR500 in 1 BOTTLETABLET5002
43598-096-30JAVYGTOR30 in 1 BOTTLETABLET302

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
43598-096-04EA - Each43598-0961990b705-0abe-4a12-9646-9f20875ad7e712022-10-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
43598-096JAVYGTOR (SAPROPTERIN DIHYDROCHLORIDE) TABLET [DR. REDDYS LABORATORIES INC]2Current NDC, Legacy NDC, 3 package rows20241123_d9f3723f-bf7d-9a72-2ef9-41c5508d6ab4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
JAVYGTORSAPROPTERIN DIHYDROCHLORIDEDr. Reddys Laboratories Incd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42024-10-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207685
application number: ANDA207685
ndc (product): 43598-096

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2612671JAVYGTOR 100 MG Oral TabletPSNd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42
1486687sapropterin dihydrochloride 100 MG Oral TabletPSNd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42
2612671sapropterin dihydrochloride 100 MG Oral Tablet [Javygtor]SBDd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42
1486687sapropterin dihydrochloride 100 MG Oral TabletSCDd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42
2612671Javygtor 100 MG (equivalent to sapropterin 76.8 MG) Oral TabletSYd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42
2612671Javygtor 100 MG Oral TabletSYd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42
1486687sapropterin dihydrochloride 100 MG Soluble TabletSYd9f3723f-bf7d-9a72-2ef9-41c5508d6ab42

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
43598-096-0443598009604120 TABLET in 1 BOTTLE (43598-096-04) 120 tablet2022-10-030000-00-00NoNoCurrent
43598-096-0543598009605500 TABLET in 1 BOTTLE (43598-096-05) 500 tablet2022-10-030000-00-00NoNoCurrent
43598-096-304359800963030 TABLET in 1 BOTTLE (43598-096-30) 30 tablet2022-10-030000-00-00NoNoCurrent