PREZCOBIX

Product NDC
50090-1723
11-digit product format
500901723
Labeler code
50090
Product ID
50090-1723_c5bd2c9e-5b7b-4404-bcd2-a82a46da19d8
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
DARUNAVIR ETHANOLATE and COBICISTAT
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
A-S Medication Solutions
Application
NDA205395
Marketing category
NDA
Marketing start
2015-01-31
Substance
COBICISTAT; DARUNAVIR ETHANOLATE
Active strength
150; 800 mg/1; mg/1
Pharmacologic classes
Breast Cancer Resistance Protein Inhibitors [MoA], Cytochrome P450 2D6 Inhibitors [MoA], Cytochrome P450 2D6 Inhibitors [MoA], Cytochrome P450 3A Inhibitor [EPC], Cytochrome P450 3A Inhibitors [MoA], Cytochrome P450 3A Inhibitors [MoA], HIV Protease Inhibitors [MoA], Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA], Organic Anion Transporting Polypeptide 1B1 Inhibitors [MoA], Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA], Protease Inhibitor [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N205395-001PREZCOBIXCOBICISTAT; DARUNAVIR ETHANOLATE150MG;EQ 800MG BASETABLET / ORALRLD, RS2015-01-29
N205395-002PREZCOBIXCOBICISTAT; DARUNAVIR ETHANOLATE150MG;EQ 675MG BASETABLET / ORALRLD, RS2025-03-21

Orange Book patents#

Current patent rows page 1 of 1 · 10 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N205395-00177006452026-12-26Drug substance, Drug product2015-02-26
N205395-0017700645*PED2027-06-26Pediatric extension
N205395-00181483742029-09-03U-1279Drug substance, Drug product2015-02-26
N205395-00181483742029-09-03U-2939Drug substance, Drug product2015-02-26
N205395-00181483742029-09-03U-4162Drug substance, Drug product2015-02-26
N205395-001100397182032-10-06Drug product2018-09-05
N205395-00277006452026-12-26Drug substance, Drug product2025-04-16
N205395-0027700645*PED2027-06-26Pediatric extension
N205395-00281483742029-09-03U-4162Drug substance, Drug product2025-04-16
N205395-002100397182032-10-06Drug product2025-04-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 45 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N205395-001PREZCOBIX150MG;EQ 800MG BASETABLET / ORALRLD, RS2015-01-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-002PREZCOBIX150MG;EQ 675MG BASETABLET / ORALRLD2025-03-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-001PREZCOBIX150MG;EQ 800MG BASETABLET / ORALRLD, RS2015-01-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-002PREZCOBIX150MG;EQ 675MG BASETABLET / ORALRLD2025-03-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08N205395-001PREZCOBIX150MG;EQ 800MG BASETABLET / ORALRLD, RS2015-01-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-002PREZCOBIX150MG;EQ 675MG BASETABLET / ORALRLD2025-03-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-2903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-292680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-295bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-2979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-291e350fbaab3a…
2024-05-31 18:47 UTC2024-05N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-298072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-295c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-295d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-294b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-2974a2ff9319b5…
2022-03-09 01:35 UTC2022-03N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-2987673890dc5c…
2021-03-12 10:30 UTC2021-03N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-295aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-298869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-293f01610625f2…
2019-09-15 20:21 UTC2019-09N205395-001PREZCOBIX150MG;EQ 800MG BASETABLET / ORALRLD, RS2015-01-29b00525d2431f…
2019-07-19 19:46 UTC2019-07N205395-001PREZCOBIX150MG;EQ 800MG BASETABLET / ORALRLD, RS2015-01-29ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-296a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-291c564ffb4f44…
2023-12-20 04:57 UTC2023-12N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-299b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-293f0d92c62455…
2023-05-13 08:27 UTC2023-05N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-29053a50430f4f…
2023-01-26 05:58 UTC2023-01N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-293bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N205395-001PREZCOBIX150MG;800MGTABLET / ORALRLD, RS2015-01-293a93d1ddd44b…

Observed Orange Book patent history#

Patent history page 1 of 8 · 311 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N205395-00177006452026-12-26Drug substance, Drug product2015-02-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-0017700645*PED2027-06-26Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-00181483742029-09-03U-1279Drug substance, Drug product2015-02-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-00181483742029-09-03U-4162Drug substance, Drug product2015-02-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-00181483742029-09-03U-2939Drug substance, Drug product2015-02-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-001100397182032-10-06Drug product2018-09-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-00277006452026-12-26Drug substance, Drug product2025-04-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-0027700645*PED2027-06-26Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-00281483742029-09-03U-4162Drug substance, Drug product2025-04-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205395-002100397182032-10-06Drug product2025-04-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-00177006452026-12-26Drug substance, Drug product2015-02-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-0017700645*PED2027-06-26Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-00181483742029-09-03U-1279Drug substance, Drug product2015-02-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-00181483742029-09-03U-4162Drug substance, Drug product2015-02-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-00181483742029-09-03U-2939Drug substance, Drug product2015-02-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-001100397182032-10-06Drug product2018-09-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-00277006452026-12-26Drug substance, Drug product2025-04-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-0027700645*PED2027-06-26Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-00281483742029-09-03U-4162Drug substance, Drug product2025-04-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205395-002100397182032-10-06Drug product2025-04-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N205395-00177006452026-12-26Drug substance, Drug product2015-02-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-0017700645*PED2027-06-26Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-00181483742029-09-03U-1279Drug substance, Drug product2015-02-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-00181483742029-09-03U-4162Drug substance, Drug product2015-02-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-00181483742029-09-03U-2939Drug substance, Drug product2015-02-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-001100397182032-10-06Drug product2018-09-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-00277006452026-12-26Drug substance, Drug product2025-04-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-0027700645*PED2027-06-26Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-00281483742029-09-03U-4162Drug substance, Drug product2025-04-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205395-002100397182032-10-06Drug product2025-04-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205395-00177006452026-12-26Drug substance, Drug product2015-02-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205395-0017700645*PED2027-06-26Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205395-00181483742029-09-03U-1279Drug substance, Drug product2015-02-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205395-00181483742029-09-03U-2939Drug substance, Drug product2015-02-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205395-001100397182032-10-06Drug product2018-09-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205395-00177006452026-12-26Drug substance, Drug product2015-02-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205395-0017700645*PED2027-06-26Pediatric extensionb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205395-00181483742029-09-03U-1279Drug substance, Drug product2015-02-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205395-00181483742029-09-03U-2939Drug substance, Drug product2015-02-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205395-001100397182032-10-06Drug product2018-09-05b8a1b40f171c…

Additional Listing Data#

Finished product
Yes
Brand name base
PREZCOBIX
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DARUNAVIR ETHANOLATE150 mg/1
COBICISTAT800 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
33O78XF0BWInternal UNII lookup
LW2E03M5PGInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1600704Internal RxNorm lookup
1600710Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
16ca460a-3c89-4697-8f45-972615a2a518Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
81157882-d7f5-4b49-9a52-b2a0c7e54020Product name220260107
12fd8c59-0b3a-2882-9cdb-92782ec03e2fProduct name620251113
594e2c86-3079-4e6e-96c9-48f7a8afc78dProduct name120230718
a56d673d-fa42-4b0e-b5ce-e65a5eab34b7Product name120180911
7fd46899-3505-4ed4-b856-6b2509a76004Product name120151123
8abcd50f-6149-4309-942e-836623ca381dProduct name120150401
248d7995-abf1-4569-b3c6-f9ebc230e8efProduct name120150323
0583b5e6-2e6e-c94b-9ff6-81a81ba199deProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50090-1723-0PREZCOBIX30 in 1 BOTTLETABLET, FILM COATED309

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-1723-0EA - Each50090-1723751ec0fb-c62f-489d-bde6-79fa2bf30d1712023-01-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50090-1723PREZCOBIX (DARUNAVIR ETHANOLATE AND COBICISTAT) TABLET, FILM COATED [A-S MEDICATION SOLUTIONS]9Current NDC, Legacy NDC, 1 package rows20240103_16ca460a-3c89-4697-8f45-972615a2a518.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PREZCOBIXDARUNAVIR ETHANOLATE AND COBICISTATJanssen Products, LP9c38fdb6-d0ba-4f16-a0e3-85d9ec334d9f2026-02-01Warnings, Adverse reactionsExact identifier
application applno (NDA): 205395
application number: NDA205395
PREZCOBIXDARUNAVIR ETHANOLATE AND COBICISTATA-S Medication Solutions16ca460a-3c89-4697-8f45-972615a2a5182024-01-02Warnings, Adverse reactionsExact identifier
application applno (NDA): 205395
application number: NDA205395
ndc (product): 50090-1723

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1600704darunavir 800 MG / cobicistat 150 MG Oral TabletPSN16ca460a-3c89-4697-8f45-972615a2a5189
1600710Prezcobix 800 MG / 150 MG Oral TabletPSN16ca460a-3c89-4697-8f45-972615a2a5189
1600710cobicistat 150 MG / darunavir 800 MG Oral Tablet [Prezcobix]SBD16ca460a-3c89-4697-8f45-972615a2a5189
1600704cobicistat 150 MG / darunavir 800 MG Oral TabletSCD16ca460a-3c89-4697-8f45-972615a2a5189
1600710Prezcobix 800 MG (as darunavir ethanolate ) / 150 MG Oral TabletSY16ca460a-3c89-4697-8f45-972615a2a5189

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
50090-1723-05009017230030 TABLET, FILM COATED in 1 BOTTLE (50090-1723-0) 2015-03-040000-00-00NoNoCurrent