ESMOLOL HYDROCHLORIDE

Product NDC
51662-1322
11-digit product format
516621322
Labeler code
51662
Product ID
51662-1322_11c184fc-7404-be32-e063-6394a90aac35
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ESMOLOL HYDROCHLORIDE
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
HF Acquisition Co LLC, DBA HealthFirst
Application
ANDA076474
Marketing category
ANDA
Marketing start
2018-10-19
Substance
ESMOLOL HYDROCHLORIDE
Active strength
10 mg/mL
Pharmacologic classes
Adrenergic beta-Antagonists [MoA], beta-Adrenergic Blocker [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076474-001ESMOLOL HYDROCHLORIDEESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A076474-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-0231067a03dcf5…
2025-08-23 18:47 UTC2025-08A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-026a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-0203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-022680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-025bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-0279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-021e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-028072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-025c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-025d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-024b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-0274a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-0287673890dc5c…
2021-03-12 10:30 UTC2021-03A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-025aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-028869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-023f01610625f2…
2019-09-15 20:21 UTC2019-09A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02b00525d2431f…
2019-07-19 19:46 UTC2019-07A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-026a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-021c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-029b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-023f0d92c62455…
2023-05-13 08:27 UTC2023-05A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02053a50430f4f…
2023-01-26 05:58 UTC2023-01A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-023bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-023a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A076474-001ESMOLOL HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAP2005-05-02cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A076474-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076474-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A076474-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076474-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076474-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076474-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076474-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076474-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076474-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076474-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076474-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076474-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076474-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076474-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076474-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076474-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076474-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076474-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076474-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076474-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076474-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A076474-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076474-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076474-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076474-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A076474-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A076474-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076474-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076474-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076474-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076474-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076474-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076474-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076474-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A076474-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A076474-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076474-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076474-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076474-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A076474-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
ESMOLOL HYDROCHLORIDE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ESMOLOL HYDROCHLORIDE10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
V05260LC8DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1736546Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
789730fa-eaca-4986-e053-2a91aa0a5339Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a21a21e5-f36d-4c1f-8918-def921b8f7e3Product name320250124
ab3d10ea-fe48-4811-8e72-bb51600b35f9Product name520230103
9cb9173b-3912-466b-8256-366e71d49fceProduct name120190402
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
51662-1322-1ESMOLOL HYDROCHLORIDE10 mL in 1 VIALINJECTION, SOLUTION105

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
51662-1322ESMOLOL HYDROCHLORIDE INJECTION, SOLUTION [HF ACQUISITION CO LLC, DBA HEALTHFIRST]5Current NDC, Legacy NDC, 1 package rows20240220_789730fa-eaca-4986-e053-2a91aa0a5339.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Esmolol HydrochlorideESMOLOL HYDROCHLORIDEHenry Schein, Inc.9c1e3a64-0ef0-4071-ad6f-63ff8789b1982025-06-18Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076474
application number: ANDA076474
Esmolol HydrochlorideESMOLOL HYDROCHLORIDEMylan Institutional LLC94f069f9-dd52-4a69-a103-ebdb4294f0882025-02-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076474
application number: ANDA076474
ESMOLOL HYDROCHLORIDEESMOLOL HYDROCHLORIDEHF Acquisition Co LLC, DBA HealthFirst789730fa-eaca-4986-e053-2a91aa0a53392024-02-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076474
application number: ANDA076474
ndc (product): 51662-1322

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1736546esmolol HCl 100 MG in 10 ML InjectionPSN789730fa-eaca-4986-e053-2a91aa0a53395
173654610 ML esmolol hydrochloride 10 MG/ML InjectionSCD789730fa-eaca-4986-e053-2a91aa0a53395
1736546esmolol HCl 100 MG per 10 ML InjectionSY789730fa-eaca-4986-e053-2a91aa0a53395

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
51662-1322-15166213220110 mL in 1 VIAL (51662-1322-1) 10 ml2018-10-190000-00-00NoNoCurrent