TOFACITINIB

Product NDC
59651-685
11-digit product format
596510685
Labeler code
59651
Product ID
59651-685_7ce3b2ea-31b1-4429-85c7-90ebf4034c8a
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
TOFACITINIB
Dosage form
TABLET, EXTENDED RELEASE
Route
ORAL
Labeler
Aurobindo Pharma Limited
Application
ANDA218462
Marketing category
ANDA
Marketing start
2026-05-14
Substance
TOFACITINIB CITRATE
Active strength
11 mg/1
Pharmacologic classes
Janus Kinase Inhibitor [EPC], Janus Kinase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A218462-001TOFACITINIB CITRATETOFACITINIB CITRATEEQ 11MG BASETABLET, EXTENDED RELEASE / ORALAB2024-06-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A218462-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06A218462-001TOFACITINIB CITRATEEQ 11MG BASETABLET, EXTENDED RELEASE / ORALAB2024-06-03a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-01 22:54:322026-06A218462-001AB1a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TOFACITINIBTOFACITINIBAurobindo Pharma Limitede54b186f-e42a-4477-939c-8dd331045fbe2026-07-17Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218462
application number: ANDA218462
ndc (product): 59651-685

Additional Listing Data#

Finished product
Yes
Brand name base
TOFACITINIB
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TOFACITINIB CITRATE11 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
O1FF4DIV0DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1741046Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e54b186f-e42a-4477-939c-8dd331045fbeAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
10e4c2fb-ffa2-728d-14d9-1c6c2f2b27b6Product name420250623

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
59651-685-30TOFACITINIB30 in 1 BOTTLETABLET, EXTENDED RELEASE307

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1741046tofacitinib 11 MG 24HR Extended Release Oral TabletPSNe54b186f-e42a-4477-939c-8dd331045fbe7
174104624 HR tofacitinib 11 MG Extended Release Oral TabletSCDe54b186f-e42a-4477-939c-8dd331045fbe7
1741046tofacitinib 11 MG (as tofacitinib citrate 17.77 MG) 24 HR Extended Release Oral TabletSYe54b186f-e42a-4477-939c-8dd331045fbe7
1741046tofacitinib 11 MG 24 HR Extended Release Oral TabletSYe54b186f-e42a-4477-939c-8dd331045fbe7

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
59651-685-305965106853030 TABLET, EXTENDED RELEASE in 1 BOTTLE (59651-685-30) 2026-05-14NoNoCurrent