allergy relief

Product NDC: 59779-874
11-digit product format: 597790874
Labeler code: 59779
Product ID: 59779-874_5cad0028-2e5f-4960-98fc-9e94b08be368
Type: HUMAN OTC DRUG
Nonproprietary name: Diphenhydramine HCl
Dosage form: SOLUTION
Route: ORAL
Labeler: CVS Pharmacy
Application: M012
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2015-09-03
Substance: DIPHENHYDRAMINE HYDROCHLORIDE
Active strength: 12.5 mg/5mL
Pharmacologic classes: Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	59779-874	59779-874-34	D	Discontinued by firm		2026-10-23

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 1 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Archive	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	59779-874	59779-874-34	D	Discontinued by firm		excluded / ndc_excluded.zip	`d630ba8d3edf…`	`732f749b63fb…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: allergy relief
Brand name suffix: childrens
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIPHENHYDRAMINE HYDROCHLORIDE	12.5 mg/5mL

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

FDA-Initiated Inactive NDC Indexing#

NDC, Related label table
NDC	Related label
59779-874-26	CVS Pharmacy, Inc. Children’s Allergy Relief Drug Facts
59779-874-26	CVS Pharmacy, Inc. Children’s Allergy Relief Drug Facts
59779-874-26	CVS Pharmacy, Inc. Children’s Allergy Relief Drug Facts
59779-874-34	CVS Pharmacy, Inc. Children’s Allergy Relief Drug Facts
59779-874-34	CVS Pharmacy, Inc. Children’s Allergy Relief Drug Facts
59779-874-34	CVS Pharmacy, Inc. Children’s Allergy Relief Drug Facts

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
59779-874-26	allergy reliefchildrens	1 in 1 CARTON	SOLUTION	1	6
59779-874-26	allergy reliefchildrens	118 mL in 1 BOTTLE	SOLUTION	118	6
59779-874-34	allergy reliefchildrens	1 in 1 CARTON	SOLUTION	1	6
59779-874-34	allergy reliefchildrens	236 mL in 1 BOTTLE	SOLUTION	236	6

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
59779-874-26	ML - Milliliter	59779-874	4cb4a87c-bcfb-4160-b09a-2fd30df77cc3	1	2018-02-20
59779-874-34	ML - Milliliter	59779-874	18e840bb-3189-47a4-b0dc-65becdfa0083	1	2018-02-20

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
DIPHENHYDRAMINE HYDROCHLORIDE	ACTIVE INGREDIENT	TC2D6JAD40	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
DIPHENHYDRAMINE	ACTIVE MOIETY	8GTS82S83M	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
ANHYDROUS CITRIC ACID	INACTIVE INGREDIENT	XF417D3PSL	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
D&C RED NO. 33	INACTIVE INGREDIENT	9DBA0SBB0L	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
FD&C RED NO. 40	INACTIVE INGREDIENT	WZB9127XOA	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
HIGH FRUCTOSE CORN SYRUP	INACTIVE INGREDIENT	XY6UN3QB6S	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
POLOXAMER 407	INACTIVE INGREDIENT	TUF2IVW3M2	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
SODIUM BENZOATE	INACTIVE INGREDIENT	OJ245FE5EU	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
SODIUM CITRATE	INACTIVE INGREDIENT	1Q73Q2JULR	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
SORBITOL	INACTIVE INGREDIENT	506T60A25R	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	ALLERGY RELIEF CHILDRENS (DIPHENHYDRAMINE HCL) LIQUID [CVS PHARMACY]	1

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 137 of 178 · 3,551 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Effervescent Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHYLEPHRINE BITARTRATE	Topco Associates LLC	a2929bcb-fa81-4f15-b087-a9996b5e7d1f	2024-11-13	Warnings	Exact identifier application number: M012
Equate Effervescent Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE	Walmart	6271bb48-74b2-eb57-e053-2991aa0afd1b	2024-11-13	Warnings	Exact identifier application number: M012
Equaline Effervescent Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE	United Natural Foods, Inc. dba UNFI	6bf341e0-94b1-08ff-e053-2991aa0af634	2024-11-13	Warnings	Exact identifier application number: M012
Good Sense Effervescent Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE	Good Sense	cd25e250-bb8b-7e83-e053-2a95a90a2639	2024-11-13	Warnings	Exact identifier application number: M012
Top Value Effervescent Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE	Tower Laboratories Ltd	440a00b1-7960-0cc4-e054-00144ff8d46c	2024-11-13	Warnings	Exact identifier application number: M012
Top Value Effervescent Cold Relief - Orange	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE	Tower Laboratories Ltd.	c6f207e8-bc0d-853a-e053-2a95a90ac623	2024-11-13	Warnings	Exact identifier application number: M012
Effervescent Orange Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE	DOLGENCORP, LLC	7fad8e65-34fe-5313-e053-2a91aa0a56f4	2024-11-13	Warnings	Exact identifier application number: M012
Dollar General Effervescent Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHYLEPHRINE BITARTRATE	DOLGENCORP, LLC	7face5c7-f5c7-7eee-e053-2991aa0ab064	2024-11-13	Warnings	Exact identifier application number: M012
Quality Choice Effervescent Cold Relief Plus	ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE	Chain Drug Marketing Association	90622927-9682-4eb0-8c7f-894230b3dda4	2024-11-13	Warnings	Exact identifier application number: M012
Quality Choice Effervescent Cold Relief - Orange	ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE	Chain Drug Marketing Association	9f7d76f0-4f1c-a1c7-e053-2a95a90a3dca	2024-11-13	Warnings	Exact identifier application number: M012
WinCo Foods Effervescent Cold Relief	ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE	WinCo Foods, LLC	d443a030-d3d6-40e0-8fe0-329de6bc494f	2024-11-13	Warnings	Exact identifier application number: M012
careone tussin dm	DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE	American Sales Company	954fe703-9a10-4354-8b71-4d98a22a0b9f	2024-11-13	Warnings	Exact identifier application number: M012
NASAL DECONGESTANT PE	PHENYLEPHRINE HCL	A-S Medication Solutions	9d030767-dfd6-48b4-9b17-4e20c23915f3	2024-11-13	Warnings	Exact identifier application number: M012
Childrens SUDAFED PE Cold plus Cough	DEXTROMETHORPHAN HYDROBROMIDE AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	20e45243-3989-413a-bcf1-49d754ff2e44	2024-11-12	Warnings	Exact identifier application number: M012
Tukol Cough And Cold Honey Flavor	DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE	Genomma Lab USA	a4b333dc-58da-45db-87b6-6fcb8fb542b8	2024-11-12	Warnings	Exact identifier application number: M012
daytime nighttime cold and flu	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HCL	Walgreen Company	4b49137c-8fc9-43b7-b1a1-82e318237eb6	2024-11-12	Warnings	Exact identifier application number: M012
CVS Original Nasal Mist	OXYMETAZOLINE HCL	CVS PHARMACY, INC	e9c551a0-cd78-4272-b42f-36c096d26736	2024-11-12	Warnings	Exact identifier application number: M012
up and up cough plus chest congestion	DEXTROMETHORPHAN HBR, GUAIFENESIN	Target Corporation	ed5dfeb1-8f7a-46ff-ae27-3fa5de5b397c	2024-11-12	Warnings	Exact identifier application number: M012
DG Health Cold and Flu Severe	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDE	Dolgencorp Inc	b33d104b-0b4d-40c6-8345-c2c740327331	2024-11-11	Warnings	Exact identifier application number: M012
Zephrex D	PSEUDOEPHEDRINE HYDROCHLORIDE	L. Perrigo Company	5468a7e2-361b-494f-9ca3-1b62f3819f65	2024-11-11	Warnings	Exact identifier application number: M012

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1049906	diphenhydrAMINE HCl 12.5 MG in 5 mL Oral Solution	PSN	8b539dc0-5487-4b11-babd-52bf341a8947	6
1049906	diphenhydramine hydrochloride 2.5 MG/ML Oral Solution	SCD	8b539dc0-5487-4b11-babd-52bf341a8947	6
1049906	diphenhydramine HCl 12.5 MG per 5 ML Oral Solution	SY	8b539dc0-5487-4b11-babd-52bf341a8947	6
1049906	diphenhydramine hydrochloride 25 MG per 10 ML Oral Solution	SY	8b539dc0-5487-4b11-babd-52bf341a8947	6
1049906	diphenhydramine hydrochloride 50 MG per 20 ML Oral Solution	SY	8b539dc0-5487-4b11-babd-52bf341a8947	6

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
59779-874-26	59779087426	1 BOTTLE in 1 CARTON (59779-874-26) / 118 mL in 1 BOTTLE	1 bottle	2015-09-03	0000-00-00	No	No	Current
59779-874-34	59779087434	1 BOTTLE in 1 CARTON (59779-874-34) > 236 mL in 1 BOTTLE	1 bottle	2015-09-03	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
CVS Pharmacy, Inc. Children’s Allergy Relief Drug Facts	CVS Pharmacy	2026-09-23	HUMAN OTC DRUG LABEL	7