FDA.reportPublic FDA data

ImproVue

Product NDC
62144-5510
11-digit product format
621445510
Labeler code
62144
Product ID
62144-5510_8d8a7585-2067-470f-912c-e62ab6277ec2
Type
HUMAN OTC DRUG
Nonproprietary name
HYPROMELLOSE 2208 (15000 MPA.S)
Dosage form
SOLUTION/ DROPS
Route
OPHTHALMIC
Labeler
Oculus Surgical, Inc.
Application
M018
Marketing category
OTC MONOGRAPH DRUG
Marketing start
2014-06-25
Substance
HYPROMELLOSE 2208 (15000 MPA.S)
Active strength
17 mg/mL
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 4 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage62144-5510-5ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage62144-5510-50efc9e666f02…f202fb6c5f17…

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product
Yes
Brand name base
ImproVue
Brand name suffix
Lubricant
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
HYPROMELLOSE 2208 (15000 MPA.S)17 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
Z78RG6M2N2Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1540361Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
63b82129-4848-47c5-bf92-ec4b1a9e9974Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
9e37788c-b1bf-42ae-aac9-b60601606144Product name820260122
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2Product name520250304
1527ac37-808d-43be-a63e-74e1258dbe46Product name920250219
bed0530e-f939-4541-956b-6928a2f6404fProduct name120241008
cefa60e2-a5b5-493e-9c54-24735b7dc509Product name620240814
362d7abb-94e6-4c60-9a58-266894157713Product name120231023
9fcb7a91-de07-4f00-aabf-e4d6fda403d5Product name820230322
6bd95106-a412-1dad-b9cc-4cb74bfb27ceProduct name220230315
9badc7be-250a-44ab-aa36-926af3f02679Product name120210527
0ec3537a-6c9b-432a-896c-b9ea8723049aProduct name920200701
444b3e50-f226-46ef-bfca-2e7035d140cdProduct name120190611
816b97af-edc5-4060-aff1-b814bdbcad50Product name120190415
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
7916de40-e296-41f0-b811-6d0df1a33e2cProduct name920180627
cefa60e2-a5b5-493e-9c54-24735b7dc509Product name220171212
419aab54-5d5a-4146-9453-026d4a9991beProduct name220170525
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
290f523a-f9db-9774-b5a9-e1f908ac1782Product name120150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
89dac932-b90a-4410-9ab1-84c53e57de25Product name120150316
5668b646-cd56-c3c7-bdea-3f6b1a8840dbProduct name120140508
810ab97e-f109-f41c-7c83-6a652a9cbf43Product name120140508
87711080-88eb-65c5-b2dd-bf99e700a372Product name120140508
8dbefedf-0a0d-a224-5a3c-66dc9e11c2ddProduct name120140508
c6b65c52-69c7-df49-550a-a50c137f6218Product name120140508
ec2149b3-5c6d-5344-f757-c86411073075Product name120140508
ed912195-5da0-0f2f-6f4b-3ef17710cbe3Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
62144-5510-5ImproVueLubricant6 in 1 CARTONSOLUTION/ DROPS65
62144-5510-5ImproVueLubricant1 in 1 POUCHSOLUTION/ DROPS15

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
62144-5510-5ML - Milliliter62144-551058aea7da-9ad9-4a80-b951-b0aad85e1fd712015-10-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
HYPROMELLOSE 2208 (15000 MPA.S)ACTIVE INGREDIENTZ78RG6M2N2IMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
HYPROMELLOSE 2208 (15000 MPA.S)ACTIVE MOIETYZ78RG6M2N2IMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Calcium ChlorideINACTIVE INGREDIENTM4I0D6VV5MIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Hydrochloric AcidINACTIVE INGREDIENTQTT17582CBIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Magnesium ChlorideINACTIVE INGREDIENT02F3473H9OIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Potassium ChlorideINACTIVE INGREDIENT660YQ98I10IMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Sodium AcetateINACTIVE INGREDIENT4550K0SC9BIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Sodium ChlorideINACTIVE INGREDIENT451W47IQ8XIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Sodium HydroxideINACTIVE INGREDIENT55X04QC32IIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
Trisodium Citrate DihydrateINACTIVE INGREDIENTB22547B95KIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1
WaterINACTIVE INGREDIENT059QF0KO0RIMPROVUE (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
62144-5510IMPROVUE LUBRICANT (HYPROMELLOSE 2208 (15000 MPA.S)) SOLUTION/ DROPS [OCULUS SURGICAL, INC.]5Current NDC, Legacy NDC, 2 package rows20250124_63b82129-4848-47c5-bf92-ec4b1a9e9974.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 5 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Lubricant Eye DropsCARBOXYMETHYLCELLULOSE SODIUMRedicare LLC4d1e5089-22b0-7b3f-e063-6294a90a346a2026-03-16WarningsExact identifier
application number: M018
Leader Ultra Lubricating Eye DropsPOLYETHYLENE GLYCOL 400, PROPYLENE GLYCOLCardinal Healthd7f011a2-05ba-47c3-9519-d31602e105c72026-03-12WarningsExact identifier
application number: M018
Leader Restorative Formula Lubricant Eye DropsPROPYLENE GLYCOLCardinal Health87fef7e4-e5a8-4aad-94d2-f80f34826d972026-03-12WarningsExact identifier
application number: M018
Leader Advanced Relief Eye DropsDEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCLCardinal Health5c5d6c13-9b51-48f0-8627-b60b0f707fd32026-03-12WarningsExact identifier
application number: M018
Focus PIHYPROMELLOSE EYE DROPS 0.7%COVALENT MEDICALe9b2afdd-049a-3987-e053-2a95a90a6cbb2026-03-09WarningsExact identifier
application number: M018
Rain Renewal Eye DropsCARBOXYMETHYLCELLULOSE SODIUMRain Eye Drops, LLCbb451b22-c4f6-291d-e053-2a95a90a78012026-03-06WarningsExact identifier
application number: M018
Complete Eye Relief Sterile Lubricant Eye DropsHYDROXYETHYL CELLULOSESimilasan Corporation4c49493a-70f9-0fde-e063-6394a90aea202026-03-05WarningsExact identifier
application number: M018
Dry Eye Relief Sterile Lubricant Eye DropsGLYCERINSimilasan Corporation4c4cce1c-392e-354d-e063-6294a90a0ca32026-03-05WarningsExact identifier
application number: M018
Irritated Eye Relief Sterile Lubricant Eye DropsHYDROXYETHYL CELLULOSESimilasan Corporation4c4ddcdf-3037-c9cd-e063-6294a90a16d52026-03-05WarningsExact identifier
application number: M018
Refresh Optive Mega-3 PFCARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN, POLYSORBATE 80Allergan, Inc.326cb5d6-c784-404f-9a13-6d69262dda6e2026-03-01WarningsExact identifier
application number: M018
Discount Drug Mart Lubricant Eye DropsCARBOXYMETHYLCELLULOSE SODIUMDiscount Drug Mart4ba1b369-54e2-5224-e063-6394a90a47692026-02-25WarningsExact identifier
application number: M018
Lubricant Eye DropsCARBOXYMETHYLCELLULOSE SODIUMKC Pharmaceuticals, Inc.4bafa882-50b7-e3e2-e063-6294a90a76e32026-02-25WarningsExact identifier
application number: M018
Viva Hydration BoostGLYCERINNomax Inc174193b2-65eb-b5fd-e063-6394a90a9cd02026-02-10WarningsExact identifier
application number: M018
Droptics Performance Eye DropsNAPHAZOLINE HYDROCHLORIDE, PROPYLENE GLYCOLDroptics LLC20fd6822-a7fd-4593-92bb-0a07260893e22026-02-09WarningsExact identifier
application number: M018
GoodSense Eye Drops Advanced Relief MoisturizerDEXTRAN, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCLSportpharm LLC8d58dcbb-72a0-41f0-9eeb-613072a6d7ae2026-02-06WarningsExact identifier
application number: M018
MINIDROPSLUBRICANT EYE DROPSOptics Laboratory, Incc13c5f91-50df-471c-a7c9-1747a2ac12502026-02-03WarningsExact identifier
application number: M018
OptaseWHITE PETROLATUM, LANOLINScope Health Incc1991caa-51b9-13d1-e053-2995a90a12932026-01-31WarningsExact identifier
application number: M018
OptaseGLYCERINScope Health Inc376e0289-28e9-e87f-e063-6294a90a3b042026-01-30WarningsExact identifier
application number: M018
OptaseGLYCERINScope Health Inc10c3e31d-779d-8ff6-e063-6294a90acd392026-01-30WarningsExact identifier
application number: M018
OptaseGLYCERINScope Health Inc9e96976b-2990-79e0-e053-2995a90a0f292026-01-30WarningsExact identifier
application number: M018

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1540361hypromellose 1.7 % Ophthalmic SolutionPSN63b82129-4848-47c5-bf92-ec4b1a9e99745
1540361hypromellose 17 MG/ML Ophthalmic SolutionSCD63b82129-4848-47c5-bf92-ec4b1a9e99745
1540361hypromellose 1.7 % Ophthalmic SolutionSY63b82129-4848-47c5-bf92-ec4b1a9e99745

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
62144-5510-5621445510056 POUCH in 1 CARTON (62144-5510-5) / 1 SYRINGE, PLASTIC in 1 POUCH / 2 mL in 1 SYRINGE, PLASTIC6 pouch2014-06-250000-00-00NoNoCurrent