XELJANZ

Product NDC
63539-029
11-digit product format
635390029
Labeler code
63539
Product ID
63539-029_184c6caf-b874-4b42-9a0d-30219f3fd2ef
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
tofacitinib
Dosage form
SOLUTION
Route
ORAL
Labeler
U.S. Pharmaceuticals
Application
NDA213082
Marketing category
NDA
Marketing start
2021-02-08
Substance
TOFACITINIB CITRATE
Active strength
1 mg/mL
Pharmacologic classes
Janus Kinase Inhibitor [EPC], Janus Kinase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N213082-001XELJANZTOFACITINIB CITRATEEQ 1MG BASE/MLSOLUTION / ORALAARLD, RS2020-09-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N213082-001AA

Orange Book patents#

Current patent rows page 1 of 1 · 2 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N213082-001RE417832025-12-08Drug substance2020-10-22
N213082-001RE41783*PED2026-06-08Pediatric extension

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N213082-001M-142028-02-21
N213082-001PED2028-08-21

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N213082-001XELJANZEQ 1MG BASE/MLSOLUTION / ORALAARLD, RS2020-09-25a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-01 22:54:322026-06N213082-001AA1a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-01 22:54:322026-06N213082-001RE417832025-12-08Drug substance2020-10-22a50c72e98297…
2026-08-01 22:54:322026-06N213082-001RE41783*PED2026-06-08Pediatric extensiona50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-01 22:54:322026-06N213082-001M-142028-02-21a50c72e98297…
2026-08-01 22:54:322026-06N213082-001PED2028-08-21a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
XELJANZTOFACITINIBU.S. Pharmaceuticals68e3d6b2-7838-4d2d-a417-09d919b43e132026-07-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 213082
application number: NDA213082
ndc (product): 63539-029
XELJANZ XRTOFACITINIBPfizer Laboratories Div Pfizer Inccf74ba2f-afc5-4baa-8594-979c889a58312026-07-12Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 213082
application number: NDA213082

Additional Listing Data#

Finished product
Yes
Brand name base
XELJANZ
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TOFACITINIB CITRATE1 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
O1FF4DIV0DInternal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
68e3d6b2-7838-4d2d-a417-09d919b43e13Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
10e4c2fb-ffa2-728d-14d9-1c6c2f2b27b6Product name420250623
362d7abb-94e6-4c60-9a58-266894157713Product name120231023
816b97af-edc5-4060-aff1-b814bdbcad50Product name120190415
419aab54-5d5a-4146-9453-026d4a9991beProduct name220170525
89dac932-b90a-4410-9ab1-84c53e57de25Product name120150316
d723478e-ad4a-ec23-6bd7-cfe33e1e3840Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63539-029-01XELJANZ240 mL in 1 BOTTLESOLUTION24017
63539-029-02XELJANZ1 in 1 CARTONSOLUTION117

DailyMed Socrata Ingredients#

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2478433tofacitinib 1 MG/mL Oral SolutionPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
2048566tofacitinib 10 MG Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
1741046tofacitinib 11 MG 24HR Extended Release Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
2273113tofacitinib 22 MG 24HR Extended Release Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
1357541tofacitinib 5 MG Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
2478437Xeljanz 1 MG/mL Oral SolutionPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
2048568Xeljanz 10 MG Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
1357547Xeljanz 5 MG Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
1741049Xeljanz XR 11 MG 24HR Extended Release Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
2273115Xeljanz XR 22 MG 24HR Extended Release Oral TabletPSN68e3d6b2-7838-4d2d-a417-09d919b43e1317
174104924 HR tofacitinib 11 MG Extended Release Oral Tablet [Xeljanz]SBD68e3d6b2-7838-4d2d-a417-09d919b43e1317
227311524 HR tofacitinib 22 MG Extended Release Oral Tablet [Xeljanz]SBD68e3d6b2-7838-4d2d-a417-09d919b43e1317
2478437tofacitinib 1 MG/ML Oral Solution [Xeljanz]SBD68e3d6b2-7838-4d2d-a417-09d919b43e1317
2048568tofacitinib 10 MG Oral Tablet [Xeljanz]SBD68e3d6b2-7838-4d2d-a417-09d919b43e1317
1357547tofacitinib 5 MG Oral Tablet [Xeljanz]SBD68e3d6b2-7838-4d2d-a417-09d919b43e1317
174104624 HR tofacitinib 11 MG Extended Release Oral TabletSCD68e3d6b2-7838-4d2d-a417-09d919b43e1317
227311324 HR tofacitinib 22 MG Extended Release Oral TabletSCD68e3d6b2-7838-4d2d-a417-09d919b43e1317
2478433tofacitinib 1 MG/ML Oral SolutionSCD68e3d6b2-7838-4d2d-a417-09d919b43e1317
2048566tofacitinib 10 MG Oral TabletSCD68e3d6b2-7838-4d2d-a417-09d919b43e1317
1357541tofacitinib 5 MG Oral TabletSCD68e3d6b2-7838-4d2d-a417-09d919b43e1317
2048566tofacitinib 10 MG (as tofacitinib citrate 16 MG) Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
1741046tofacitinib 11 MG (as tofacitinib citrate 17.77 MG) 24 HR Extended Release Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
1741046tofacitinib 11 MG 24 HR Extended Release Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
1357541tofacitinib 5 MG (as tofacitinib citrate 8 MG) Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
2478437Xeljanz 1 MG/ML Oral SolutionSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
2048568Xeljanz 10 MG (as tofacitinib citrate 16 MG) Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
2048568Xeljanz 10 MG Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
1357547Xeljanz 5 MG (as tofacitinib citrate 8 MG) Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
1357547Xeljanz 5 MG Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
1741049Xeljanz XR 11 MG (as tofacitinib citrate 17.77 MG) 24 HR Extended Release Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
1741049Xeljanz XR 11 MG 24 HR Extended Release Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317
2273115Xeljanz XR 22 MG (as tofacitinib citrate 35.54 MG) 24 HR Extended Release Oral TabletSY68e3d6b2-7838-4d2d-a417-09d919b43e1317

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
63539-029-0163539002901240 mL in 1 BOTTLE240 mlHistorical
63539-029-02635390029021 BOTTLE in 1 CARTON (63539-029-02) / 240 mL in 1 BOTTLE (63539-029-01) 1 bottle2021-02-08NoNoCurrent