Nitisinone

Product NDC
63629-2234
11-digit product format
636292234
Labeler code
63629
Product ID
63629-2234_a6f7c9c3-8dbd-4e67-bed6-6a1c1ca122db
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Nitisinone
Dosage form
CAPSULE
Route
ORAL
Labeler
Bryant Ranch Prepack
Application
ANDA211041
Marketing category
ANDA
Marketing start
2019-10-04
Substance
NITISINONE
Active strength
2 mg/1
Pharmacologic classes
4-Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor [EPC], Cytochrome P450 2C9 Inhibitors [MoA], Cytochrome P450 2E1 Inducers [MoA], Hydroxyphenylpyruvate Dioxygenase Inhibitors [MoA], Organic Anion Transporter 1 Inhibitors [MoA], Organic Anion Transporter 3 Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211041-001NITISINONENITISINONE2MGCAPSULE / ORALAB2019-08-26
A211041-002NITISINONENITISINONE5MGCAPSULE / ORALAB2019-08-26
A211041-003NITISINONENITISINONE10MGCAPSULE / ORALAB2019-08-26

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A211041-001AB
A211041-002AB
A211041-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-26caaa826d4ba7…
2026-08-18 06:07:402026-07A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-26caaa826d4ba7…
2026-08-18 06:07:402026-07A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-26caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-26d06236e962d9…
2024-10-29 15:01 UTC2024-10A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-26d06236e962d9…
2024-10-29 15:01 UTC2024-10A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211041-002NITISINONE5MGCAPSULE / ORALAB2019-08-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211041-003NITISINONE10MGCAPSULE / ORALAB2019-08-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211041-001NITISINONE2MGCAPSULE / ORALAB2019-08-261e350fbaab3a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A211041-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A211041-002AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A211041-003AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211041-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211041-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211041-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211041-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211041-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211041-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211041-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211041-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211041-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211041-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211041-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211041-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211041-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211041-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211041-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211041-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211041-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211041-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211041-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211041-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211041-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211041-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211041-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211041-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211041-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211041-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211041-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211041-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211041-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211041-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211041-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211041-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211041-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211041-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211041-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211041-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211041-001AB11e350fbaab3a…

Additional Listing Data#

Finished product
Yes
Brand name base
Nitisinone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NITISINONE2 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
K5BN214699Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
351173Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
b7c38003-6899-4508-a69a-aef1231de22cAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
30289e20-d00d-4455-8aae-af8add8f10eeProduct name420240529
5b3e65b0-2e25-4346-b6a5-74172e0cd130Product name120170824
689eee6a-c9bd-41ef-86ac-b494143eb282Product name220160804

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63629-2234-1Nitisinone60 in 1 BOTTLECAPSULE60104
63629-2234-1Nitisinone1 in 1 CARTONCAPSULE1104

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
63629-2234-1EA - Each63629-2234e28e3bfd-96c4-435b-8a2d-893289afec5a12021-05-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
63629-2234NITISINONE CAPSULE [BRYANT RANCH PREPACK]104Current NDC, Legacy NDC, 2 package rows20240112_b7c38003-6899-4508-a69a-aef1231de22c.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
NitisinoneNITISINONEPar Health USA, LLC437868f5-1c9e-4b0f-8a03-77df8ac0900d2026-08-06Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211041
application number: ANDA211041
NitisinoneNITISINONEBryant Ranch Prepackc1b3adc8-02fa-4e22-8c05-8f32b586e53f2024-01-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211041
application number: ANDA211041
NitisinoneNITISINONEBryant Ranch Prepack8cec0318-9f55-4340-b14b-5886356192512024-01-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211041
application number: ANDA211041
NitisinoneNITISINONEBryant Ranch Prepackb7c38003-6899-4508-a69a-aef1231de22c2024-01-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211041
application number: ANDA211041
ndc (product): 63629-2234

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
351173nitisinone 2 MG Oral CapsulePSNb7c38003-6899-4508-a69a-aef1231de22c104
351173nitisinone 2 MG Oral CapsuleSCDb7c38003-6899-4508-a69a-aef1231de22c104

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
63629-2234-1636292234011 BOTTLE in 1 CARTON (63629-2234-1) / 60 CAPSULE in 1 BOTTLE1 bottle2021-03-220000-00-00NoNoCurrent