Metolazone

Product NDC
63629-8733
11-digit product format
636298733
Labeler code
63629
Product ID
63629-8733_fe0db243-235b-4a8b-9d1c-e14f75e1baea
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Metolazone
Dosage form
TABLET
Route
ORAL
Labeler
Bryant Ranch Prepack
Application
ANDA076466
Marketing category
ANDA
Marketing start
2003-12-19
Substance
METOLAZONE
Active strength
5 mg/1
Pharmacologic classes
Increased Diuresis [PE], Thiazide-like Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076466-001METOLAZONEMETOLAZONE5MGTABLET / ORALABRS2003-12-19
A076466-002METOLAZONEMETOLAZONE10MGTABLET / ORALABRS2003-12-19

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A076466-001AB
A076466-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-1931067a03dcf5…
2025-08-23 18:47 UTC2025-08A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-196a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-1903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-192680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-195bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19d06236e962d9…
2024-10-29 15:01 UTC2024-10A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-1979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-191e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-198072bd15b7f6…
2024-05-31 18:47 UTC2024-05A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-198072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-195c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-195c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-195d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-195d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-194b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-194b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076466-001METOLAZONE5MGTABLET / ORALAB2003-12-1974a2ff9319b5…
2019-12-13 00:20 UTC2019-12A076466-002METOLAZONE10MGTABLET / ORALAB2003-12-1974a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076466-001METOLAZONE5MGTABLET / ORALABRS2003-12-19782e0a99824c…
2021-12-28 21:50 UTC2021-12A076466-002METOLAZONE10MGTABLET / ORALABRS2003-12-19782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A076466-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076466-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076466-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076466-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A076466-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076466-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076466-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076466-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076466-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076466-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076466-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076466-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076466-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076466-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076466-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076466-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076466-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076466-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076466-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A076466-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076466-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076466-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076466-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076466-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076466-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076466-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076466-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A076466-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076466-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076466-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076466-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A076466-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076466-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A076466-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076466-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A076466-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076466-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A076466-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076466-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A076466-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Metolazone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METOLAZONE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
TZ7V40X7VXInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
311671Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8f8a79d5-5404-46f1-9974-47ae05e855d7Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
4e48c581-6027-290d-65f0-1b09c39dc1e8Product name620250625

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63629-8733-1Metolazone100 in 1 BOTTLETABLET100103

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
63629-8733-1EA - Each63629-873383a50734-8cc2-4571-979b-cbed7f87d29112021-10-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
63629-8733METOLAZONE TABLET [BRYANT RANCH PREPACK]103Current NDC, Legacy NDC, 1 package rows20241004_8f8a79d5-5404-46f1-9974-47ae05e855d7.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MetolazoneMETOLAZONEBryant Ranch Prepack2125b330-eb56-4310-9806-e101eae4576c2025-10-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076466
application number: ANDA076466
MetolazoneMETOLAZONESandoz Inc0b619826-2567-49d7-8972-b6da5e4467df2025-03-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076466
application number: ANDA076466
MetolazoneMETOLAZONEBryant Ranch Prepack08cb093a-b8ec-40d9-b292-2513b488d14c2024-12-24Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076466
application number: ANDA076466
MetolazoneMETOLAZONEBryant Ranch Prepack564eccca-2eba-4b6d-b6ab-1439c4c839062024-05-23Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076466
application number: ANDA076466
MetolazoneMETOLAZONEBryant Ranch Prepack8f8a79d5-5404-46f1-9974-47ae05e855d72023-12-11Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076466
application number: ANDA076466
ndc (product): 63629-8733

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
311671metOLazone 5 MG Oral TabletPSN8f8a79d5-5404-46f1-9974-47ae05e855d7103
311671metolazone 5 MG Oral TabletSCD8f8a79d5-5404-46f1-9974-47ae05e855d7103

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
63629-8733-163629873301100 TABLET in 1 BOTTLE (63629-8733-1) 100 tablet2021-08-190000-00-00NoNoCurrent