Arixtra

Product NDC
67457-595
11-digit product format
674570595
Labeler code
67457
Product ID
67457-595_8de301f7-88ad-41d7-9ec3-884cab56f943
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
fondaparinux sodium
Dosage form
INJECTION, SOLUTION
Route
SUBCUTANEOUS
Labeler
Mylan Institutional LLC
Application
NDA021345
Marketing category
NDA
Marketing start
2014-05-19
Substance
FONDAPARINUX SODIUM
Active strength
10 mg/.8mL
Pharmacologic classes
Factor Xa Inhibitor [EPC], Factor Xa Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021345-001ARIXTRAFONDAPARINUX SODIUM2.5MG/0.5ML (2.5MG/0.5ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2001-12-07
N021345-002ARIXTRAFONDAPARINUX SODIUM5MG/0.4ML (5MG/0.4ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28
N021345-003ARIXTRAFONDAPARINUX SODIUM7.5MG/0.6ML (7.5MG/0.6ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28
N021345-004ARIXTRAFONDAPARINUX SODIUM10MG/0.8ML (10MG/0.8ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
N021345-001AP
N021345-002AP
N021345-003AP
N021345-004AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 168 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N021345-001ARIXTRA2.5MG/0.5ML (2.5MG/0.5ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2001-12-07caaa826d4ba7…
2026-08-18 06:07:402026-07N021345-002ARIXTRA5MG/0.4ML (5MG/0.4ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28caaa826d4ba7…
2026-08-18 06:07:402026-07N021345-003ARIXTRA7.5MG/0.6ML (7.5MG/0.6ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28caaa826d4ba7…
2026-08-18 06:07:402026-07N021345-004ARIXTRA10MG/0.8ML (10MG/0.8ML)SOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021345-001ARIXTRA2.5MG/0.5MLSOLUTION / SUBCUTANEOUSAPRLD, RS2001-12-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021345-002ARIXTRA5MG/0.4MLSOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021345-003ARIXTRA7.5MG/0.6MLSOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021345-004ARIXTRA10MG/0.8MLSOLUTION / SUBCUTANEOUSAPRLD, RS2004-05-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-001ARIXTRA2.5MG/0.5MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2001-12-07d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-002ARIXTRA5MG/0.4MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-003ARIXTRA7.5MG/0.6MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-004ARIXTRA10MG/0.8MLINJECTABLE / SUBCUTANEOUSAPRLD, RS2004-05-28d8e5a09893c0…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 5 · 168 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N021345-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07N021345-002AP1caaa826d4ba7…
2026-08-18 06:07:402026-07N021345-003AP1caaa826d4ba7…
2026-08-18 06:07:402026-07N021345-004AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021345-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021345-002AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021345-003AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021345-004AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-002AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-003AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021345-004AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021345-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021345-002AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021345-003AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021345-004AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-003AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021345-004AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-003AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021345-004AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-003AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021345-004AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-003AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021345-004AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-002AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-003AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021345-004AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-002AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-003AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021345-004AP1d8e5a09893c0…

Additional Listing Data#

Finished product
Yes
Brand name base
Arixtra
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
FONDAPARINUX SODIUM10 mg/.8mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
X0Q6N9USOZInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 8 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
861356Internal RxNorm lookup
861358Internal RxNorm lookup
861360Internal RxNorm lookup
861362Internal RxNorm lookup
861363Internal RxNorm lookup
861364Internal RxNorm lookup
861365Internal RxNorm lookup
861366Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
d3b30c68-cf45-4b46-8ba6-72090f7ba01aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
03ac78a4-5655-4d9a-b2f1-a0919f833364Product name520250818

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
67457-595-00Arixtra0.8 mL in 1 SYRINGE, GLASSINJECTION, SOLUTION0.813
67457-595-08Arixtra10 in 1 CARTONINJECTION, SOLUTION1013

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
67457-595-00ML - Milliliter67457-5954f10aab8-4852-423e-a64d-ffc3b14bb6d812015-12-02
67457-595-08ML - Milliliter67457-5957f32e5f4-44ff-43d7-acff-6178c7887f9f12015-12-02

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
67457-595ARIXTRA (FONDAPARINUX SODIUM) INJECTION, SOLUTION [MYLAN INSTITUTIONAL LLC]13Current NDC, Legacy NDC, 2 package rows20250201_d3b30c68-cf45-4b46-8ba6-72090f7ba01a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ArixtraFONDAPARINUX SODIUMMylan Institutional LLCd3b30c68-cf45-4b46-8ba6-72090f7ba01a2024-12-10Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021345
application number: NDA021345
ndc (product): 67457-595
Fondaparinux SodiumFONDAPARINUX SODIUMMylan Institutional LLC4b65f642-87f7-4da5-a9c9-02cd1f8d9d162020-08-15Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021345
application number: NDA021345

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
861358Arixtra 10 MG in 0.8 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861366Arixtra 7.5 MG in 0.6 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861362Atrixtra 2.5 MG in 0.5 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861364Atrixtra 5 MG in 0.4 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861356fondaparinux sodium 10 MG in 0.8 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861360fondaparinux sodium 2.5 MG in 0.5 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861363fondaparinux sodium 5 MG in 0.4 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861365fondaparinux sodium 7.5 MG in 0.6 ML Prefilled SyringePSNd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613640.4 ML fondaparinux sodium 12.5 MG/ML Prefilled Syringe [Arixtra]SBDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613620.5 ML fondaparinux sodium 5 MG/ML Prefilled Syringe [Arixtra]SBDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613660.6 ML fondaparinux sodium 12.5 MG/ML Prefilled Syringe [Arixtra]SBDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613580.8 ML fondaparinux sodium 12.5 MG/ML Prefilled Syringe [Arixtra]SBDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613630.4 ML fondaparinux sodium 12.5 MG/ML Prefilled SyringeSCDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613600.5 ML fondaparinux sodium 5 MG/ML Prefilled SyringeSCDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613650.6 ML fondaparinux sodium 12.5 MG/ML Prefilled SyringeSCDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613560.8 ML fondaparinux sodium 12.5 MG/ML Prefilled SyringeSCDd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613640.4 ML Arixtra 12.5 MG/ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613620.5 ML Arixtra 5 MG/ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613660.6 ML Arixtra 12.5 MG/ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
8613580.8 ML Arixtra 12.5 MG/ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861358Arixtra 10 MG per 0.8 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861366Arixtra 7.5 MG per 0.6 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861362Atrixtra 2.5 MG per 0.5 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861364Atrixtra 5 MG per 0.4 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861356fondaparinux sodium 10 MG per 0.8 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861360fondaparinux sodium 2.5 MG per 0.5 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861363fondaparinux sodium 5 MG per 0.4 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13
861365fondaparinux sodium 7.5 MG per 0.6 ML Prefilled SyringeSYd3b30c68-cf45-4b46-8ba6-72090f7ba01a13

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
67457-595-00674570595000.8 mL in 1 SYRINGE, GLASS0.8 mlHistorical
67457-595-086745705950810 SYRINGE, GLASS in 1 CARTON (67457-595-08) / .8 mL in 1 SYRINGE, GLASS (67457-595-00) 2014-05-190000-00-00NoNoCurrent