Iluvien

Product NDC
68611-190
11-digit product format
686110190
Labeler code
68611
Product ID
68611-190_78b978f0-fc11-11f0-b558-0800200c9a66
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
fluocinolone acetonide
Dosage form
IMPLANT
Route
INTRAVITREAL
Labeler
ANI Pharmaceuticals, Inc.
Application
NDA201923
Marketing category
NDA
Marketing start
2014-10-15
Substance
FLUOCINOLONE ACETONIDE
Active strength
.19 mg/1
Pharmacologic classes
Corticosteroid Hormone Receptor Agonists [MoA], Corticosteroid [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N201923-001ILUVIENFLUOCINOLONE ACETONIDE0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26

Orange Book patents#

Current patent rows page 1 of 1 · 3 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N201923-00188712412027-08-12Drug product2014-11-12
N201923-00198490272028-11-07U-4157Drug product2025-04-03
N201923-00198490272028-11-07U-708Drug product2025-04-03

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-264b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-2674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-2687673890dc5c…
2021-03-12 10:30 UTC2021-03N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-265aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-268869cabd3fbd…
2020-11-12 02:37 UTC2020-11N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26c0c555d07b60…
2019-12-14 00:12 UTC2019-12N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-263f01610625f2…
2019-09-15 20:21 UTC2019-09N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26b00525d2431f…
2019-07-19 19:46 UTC2019-07N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-266a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-261c564ffb4f44…
2023-12-20 04:57 UTC2023-12N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-269b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-263f0d92c62455…
2023-05-13 08:27 UTC2023-05N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26053a50430f4f…
2023-01-26 05:58 UTC2023-01N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-263bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-263a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N201923-001ILUVIEN0.19MGIMPLANT / INTRAVITREALRLD, RS2014-09-26cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 2 · 67 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N201923-00188712412027-08-12Drug product2014-11-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201923-00198490272028-11-07U-708Drug product2025-04-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201923-00198490272028-11-07U-4157Drug product2025-04-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201923-00188712412027-08-12Drug product2014-11-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201923-00198490272028-11-07U-708Drug product2025-04-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201923-00198490272028-11-07U-4157Drug product2025-04-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08N201923-00188712412027-08-12Drug product2014-11-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201923-00198490272028-11-07U-708Drug product2025-04-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201923-00198490272028-11-07U-4157Drug product2025-04-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201923-00188712412027-08-12Drug product2014-11-12fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201923-00188712412027-08-12Drug product2014-11-12b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N201923-00188712412027-08-12Drug product2014-11-1203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N201923-00188712412027-08-12Drug product2014-11-122680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N201923-00188712412027-08-12Drug product2014-11-125bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N201923-00188712412027-08-12Drug product2014-11-12d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N201923-00188712412027-08-12Drug product2014-11-12d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N201923-00188712412027-08-12Drug product2014-11-1279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N201923-00188712412027-08-12Drug product2014-11-12301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N201923-00188712412027-08-12Drug product2014-11-121e350fbaab3a…
2024-05-31 18:47 UTC2024-05N201923-00188712412027-08-12Drug product2014-11-128072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N201923-00188712412027-08-12Drug product2014-11-125c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N201923-00188712412027-08-12Drug product2014-11-125d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N201923-00188712412027-08-12Drug product2014-11-124b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N201923-00162178952019-03-22U-1597Drug product2014-10-2374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N201923-00165480782019-03-22U-1597Drug product2014-10-2374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N201923-00182523072019-06-27Drug product2014-10-2374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N201923-00163759722020-04-26U-1597Drug product2014-10-2374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N201923-00188712412027-08-12Drug product2014-11-1274a2ff9319b5…
2022-03-09 01:35 UTC2022-03N201923-00188712412027-08-12Drug product2014-11-12bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N201923-00188712412027-08-12Drug product2014-11-12782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N201923-00188712412027-08-12Drug product2014-11-1287673890dc5c…
2021-03-12 10:30 UTC2021-03N201923-00188712412027-08-12Drug product2014-11-125aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N201923-00163759722020-04-26U-1597Drug product2014-10-238869cabd3fbd…
2020-12-22 03:56 UTC2020-12N201923-00188712412027-08-12Drug product2014-11-128869cabd3fbd…
2020-11-12 02:37 UTC2020-11N201923-00163759722020-04-26U-1597Drug product2014-10-23c0c555d07b60…
2020-11-12 02:37 UTC2020-11N201923-00188712412027-08-12Drug product2014-11-12c0c555d07b60…
2019-12-14 00:12 UTC2019-12N201923-00162178952019-03-22U-1597Drug product2014-10-233f01610625f2…
2019-12-14 00:12 UTC2019-12N201923-00165480782019-03-22U-1597Drug product2014-10-233f01610625f2…
2019-12-14 00:12 UTC2019-12N201923-00182523072019-06-27Drug product2014-10-233f01610625f2…
2019-12-14 00:12 UTC2019-12N201923-00163759722020-04-26U-1597Drug product2014-10-233f01610625f2…

Additional Listing Data#

Finished product
Yes
Brand name base
Iluvien
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
FLUOCINOLONE ACETONIDE.19 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
0CD5FD6S2MInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1552351Internal RxNorm lookup
1552356Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4400e471-7402-11df-93f2-0800200c9a66Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0adb2af5-1ecf-4df5-912b-16ae89228294Product name620240829
65f6255d-41cc-425f-ba54-b1bea4947886Product name520210930
5ba208e4-886f-44da-e218-ab4f4cad2c49Product name520190612
e5a2793f-318b-72fd-b734-c44ecc6f6748Product name220190213
9e453f34-aacb-44d5-a119-c0e3dc1fca2aProduct name120160622
7df2570a-c555-4d82-9189-9247c722b62cProduct name120150402
85490a6b-2306-6bf2-c51b-eb63537dc2daProduct name120140508
a78a3633-fd06-b0af-63b3-c714de3b3bfaProduct name120140508
b2d0a9c2-fd0c-a9b4-ae41-f6a4eef4fbf6Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
68611-190-02Iluvien1 in 1 TRAYIMPLANT120
68611-190-02Iluvien1 in 1 CARTONIMPLANT120

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
68611-190-02EA - Each68611-1904ac38697-b8c1-4c67-ae02-1f9b3f558a5a12015-01-05

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
FLUOCINOLONE ACETONIDEACTIVE INGREDIENT0CD5FD6S2MILUVIEN (FLUOCINOLONE ACETONIDE) IMPLANT [ALIMERA SCIENCES, INC.]8
FLUOCINOLONE ACETONIDEACTIVE MOIETY0CD5FD6S2MILUVIEN (FLUOCINOLONE ACETONIDE) IMPLANT [ALIMERA SCIENCES, INC.]8
POLYVINYL ALCOHOLINACTIVE INGREDIENT532B59J990ILUVIEN (FLUOCINOLONE ACETONIDE) IMPLANT [ALIMERA SCIENCES, INC.]8
WATERINACTIVE INGREDIENT059QF0KO0RILUVIEN (FLUOCINOLONE ACETONIDE) IMPLANT [ALIMERA SCIENCES, INC.]8

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
68611-190ILUVIEN (FLUOCINOLONE ACETONIDE) IMPLANT [ALIMERA SCIENCES, INC.]18Current NDC, Legacy NDC, 2 package rows20250326_4400e471-7402-11df-93f2-0800200c9a66.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
IluvienFLUOCINOLONE ACETONIDEANI Pharmaceuticals, Inc.4400e471-7402-11df-93f2-0800200c9a662026-01-28Warnings, Adverse reactionsExact identifier
application applno (NDA): 201923
application number: NDA201923
ndc (product): 68611-190

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1552351fluocinolone acetonide 0.19 MG Intravitreal Drug ImplantPSN4400e471-7402-11df-93f2-0800200c9a6620
1552356ILUVIEN 0.19 MG Intravitreal Drug ImplantPSN4400e471-7402-11df-93f2-0800200c9a6620
1552356fluocinolone acetonide 0.19 MG Drug Implant [Iluvien]SBD4400e471-7402-11df-93f2-0800200c9a6620
1552351fluocinolone acetonide 0.19 MG Drug ImplantSCD4400e471-7402-11df-93f2-0800200c9a6620
1552356Iluvien 0.19 MG Drug ImplantSY4400e471-7402-11df-93f2-0800200c9a6620

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
68611-190-02686110190021 TRAY in 1 CARTON (68611-190-02) / 1 APPLICATOR in 1 TRAY / 1 IMPLANT in 1 APPLICATOR1 tray2014-10-150000-00-00NoNoCurrent