neffy

Product NDC: 71872-7330
Requested package NDC: 71872-7330-1
11-digit product format: 718727330
Labeler code: 71872
Product ID: 71872-7330_2d4063dc-9f4e-71de-e063-6294a90aa599
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: epinephrine
Dosage form: SPRAY
Route: NASAL
Labeler: Medical Purchasing Solutions, LLC
Application: NDA214697
Marketing category: NDA
Marketing start: 2024-08-09
Substance: EPINEPHRINE
Active strength: 2 mg/100uL
Pharmacologic classes: Adrenergic alpha-Agonists [MoA], Adrenergic beta-Agonists [MoA], Catecholamine [EPC], Catecholamines [CS], alpha-Adrenergic Agonist [EPC], beta-Adrenergic Agonist [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N214697-001	NEFFY	EPINEPHRINE	2MG/SPRAY	SPRAY / NASAL		RLD, RS	2024-08-09
N214697-002	NEFFY	EPINEPHRINE	1MG/SPRAY	SPRAY / NASAL		RLD, RS	2025-03-05

Orange Book patents#

Current patent rows page 1 of 1 · 16 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N214697-001	10576156	2038-02-06		Drug product	2024-08-28
N214697-001	11173209	2038-02-06	U-3979		2024-08-28
N214697-001	10682414	2039-02-06	U-3979		2024-08-28
N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28
N214697-001	11717571	2039-02-06	U-3979		2024-08-28
N214697-001	11744895	2039-02-06	U-3979		2024-08-28
N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28
N214697-001	12324838	2039-02-06		Drug product	2025-06-20
N214697-002	10576156	2038-02-06		Drug product	2025-04-03
N214697-002	11173209	2038-02-06	U-3979		2025-04-03
N214697-002	10682414	2039-02-06	U-3979		2025-04-03
N214697-002	11191838	2039-02-06	U-3979	Drug product	2025-04-03
N214697-002	11717571	2039-02-06	U-3979		2025-04-03
N214697-002	11744895	2039-02-06	U-3979		2025-04-03
N214697-002	11918655	2039-02-06	U-3979		2025-04-03
N214697-002	12324838	2039-02-06		Drug product	2025-06-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	RLD / RS	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`d06236e962d9…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`a50c72e98297…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`a50c72e98297…`

Observed Orange Book patent history#

Patent history page 1 of 3 · 113 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N214697-001	10576156	2038-02-06		Drug product	2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11173209	2038-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	10682414	2039-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11717571	2039-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11744895	2039-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	12324838	2039-02-06		Drug product	2025-06-20	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	10576156	2038-02-06		Drug product	2025-04-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	11173209	2038-02-06	U-3979		2025-04-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	10682414	2039-02-06	U-3979		2025-04-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	11191838	2039-02-06	U-3979	Drug product	2025-04-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	11717571	2039-02-06	U-3979		2025-04-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	11744895	2039-02-06	U-3979		2025-04-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	11918655	2039-02-06	U-3979		2025-04-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	12324838	2039-02-06		Drug product	2025-06-20	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	10576156	2038-02-06		Drug product	2024-08-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	11173209	2038-02-06	U-3979		2024-08-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	10682414	2039-02-06	U-3979		2024-08-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	11717571	2039-02-06	U-3979		2024-08-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	11744895	2039-02-06	U-3979		2024-08-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	12324838	2039-02-06		Drug product	2025-06-20	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	10576156	2038-02-06		Drug product	2025-04-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	11173209	2038-02-06	U-3979		2025-04-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	10682414	2039-02-06	U-3979		2025-04-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	11191838	2039-02-06	U-3979	Drug product	2025-04-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	11717571	2039-02-06	U-3979		2025-04-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	11744895	2039-02-06	U-3979		2025-04-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	11918655	2039-02-06	U-3979		2025-04-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	12324838	2039-02-06		Drug product	2025-06-20	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N214697-001	10576156	2038-02-06		Drug product	2024-08-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-001	11173209	2038-02-06	U-3979		2024-08-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-001	10682414	2039-02-06	U-3979		2024-08-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-001	11717571	2039-02-06	U-3979		2024-08-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-001	11744895	2039-02-06	U-3979		2024-08-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-001	12324838	2039-02-06		Drug product	2025-06-20	`6a471c1ec25d…`

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
neffy	EPINEPHRINE	Sportpharm LLC	2052f9db-7d76-443b-b702-b6b499f9a4b8	2026-04-24	Warnings, Adverse reactions	Exact identifier application applno (NDA): 214697 application number: NDA214697
neffy	EPINEPHRINE	ARS Pharmaceuticals Operations, Inc.	a1758142-a905-401d-8961-05829f51023a	2026-04-09	Warnings, Adverse reactions	Exact identifier application applno (NDA): 214697 application number: NDA214697
neffy	EPINEPHRINE	Medical Purchasing Solutions, LLC	2d4063e8-f56c-6902-e063-6294a90a0d40	2025-02-03	Warnings, Adverse reactions	Exact identifier application applno (NDA): 214697 application number: NDA214697 ndc (package): 71872-7330-1 ndc (product): 71872-7330 ndc11 (package): 71872733001

Additional Listing Data#

Finished product: Yes
Brand name base: neffy
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
EPINEPHRINE	2 mg/100uL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
YKH834O4BH	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2693442	Internal RxNorm lookup
2693448	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2d4063e8-f56c-6902-e063-6294a90a0d40	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0b4ec9ca-d305-43fc-88dd-7a510313efe0	Product name	1	20260105
bb209f42-a85f-4fee-9d3d-c9dded168625	Product name	1	20251208
49628fc7-2031-4c28-bd31-0ef3aa8f44a3	Product name	3	20251118
cbf85893-59ef-423f-87d4-a573c000a8b9	Product name	8	20250731
b5b1095b-40cd-8a9e-b111-502545045b07	Product name	4	20250325
e190029e-423b-473c-8e04-2ada59b5b711	Product name	1	20250314
e0031c74-3853-42bc-8e10-86dbbe83992e	Product name	2	20231116
f7046b89-2016-499a-adc6-78479172abc6	Product name	1	20230425
2686d634-e712-4007-8dbf-3d37c6c4d71f	Product name	1	20181121
fa8b5901-e681-426f-82fe-54f6d81ec698	Product name	4	20180619
bd49bb86-2d32-4a7a-a594-eeda2e29af42	Product name	1	20180118
c08ab52f-2fc8-4409-9d9f-ed8edc0bd070	Product name	1	20171221
3becbe78-12d9-4ad2-9b4c-1e36f8d1303a	Product name	1	20170815

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
71872-7330-1	neffy	1 in 1 BLISTER PACK	SPRAY	1		1
71872-7330-1	neffy	1 in 1 BAG	SPRAY	1		1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
71872-7330	NEFFY (EPINEPHRINE) SPRAY [MEDICAL PURCHASING SOLUTIONS, LLC]	1	Current NDC, 2 package rows	20250205_2d4063e8-f56c-6902-e063-6294a90a0d40.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
YKH834O4BH	EPINEPHRINE	51-43-4	EPINEPHRINE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2693442	EPINEPHrine 2 MG in 0.1 ML Nasal Spray	PSN	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	neffy 2 MG in 0.1 ML Nasal Spray	PSN	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	epinephrine 20 MG/ML Nasal Spray [Neffy]	SBD	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693442	epinephrine 20 MG/ML Nasal Spray	SCD	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693442	epinephrine 2 MG per 0.1 ML Nasal Spray	SY	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	Neffy 2 MG per 0.1 ML Nasal Spray	SY	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	Neffy 20 MG/ML Nasal Spray	SY	2d4063e8-f56c-6902-e063-6294a90a0d40	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
71872-7330-1	71872733001	1 BLISTER PACK in 1 BAG (71872-7330-1) / 1 VIAL, SINGLE-DOSE in 1 BLISTER PACK / 100 uL in 1 VIAL, SINGLE-DOSE	1 blister pack	2025-01-16	No	No	Current