oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Zicam Sinus Relief]

RxCUI: 1001084
RxNorm name: oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Zicam Sinus Relief]
Display name: ZICAM SINUS RELIEF (Nasal)
Full name: oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Zicam Sinus Relief]
Term type: SBD
Status: Active
Strength: 0.05%
Dose form: Spray
Route: Nasal
Updated: 2026-10-27 17:45:56

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 092010
Active start: 092010
Multiple ingredient: NO
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
oxymetazoline hydrochloride	0.5 MG / 1 ML	oxymetazoline	oxymetazoline hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Nasal Spray	126542

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
oxymetazoline	7812

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	Zicam Sinus Relief 0.05 % Nasal Spray	1	NAMES
RxNorm Name	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Zicam Sinus Relief]	1	NAMES
RxNorm Synonym	3 linked values Zicam Extreme Congestion Relief 0.05 % Nasal Spray Zicam Sinus Relief 0.05 % Nasal Spray Zicam Sinus Relief 0.5 MG/ML Nasal Spray	3	NAMES
TTY	SBD	1	ATTRIBUTES
SPL_SET_ID	2 linked values ccada339-656c-a461-e053-2a95a90a3479 d916f7ff-84b7-57ef-e053-2995a90a3efa	2	CODES
RxCUI	1001084	1	CODES
MMSL_CODE	BD4399	1	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
10237-464-15	10237-464	Zicam Extreme Congestion Relief oxymetazoline hydrochloride	Church & Dwight Co., Inc.	M012
10237-471-15	10237-471	Zicam Intense Sinus Relief oxymetazoline hydrochloride	Church & Dwight Co., Inc.	M012

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
M012	10237-464	Zicam Extreme Congestion Relief oxymetazoline hydrochloride	OTC MONOGRAPH DRUG	Church & Dwight Co., Inc.

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 6 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
10237046415	rxnav_ndcs	yes
10237047115	rxnav_ndcs	yes
62750000510	rxnav_ndcs	yes
62750000610	rxnav_ndcs	yes
62750000511	rxnav_historical
62750000611	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Zicam Intense Sinus Relief	OXYMETAZOLINE HYDROCHLORIDE	Church & Dwight Co., Inc.	d916f7ff-84b7-57ef-e053-2995a90a3efa	2026-08-31	Warnings	Exact identifier ndc (package): 10237-471-15 ndc (product): 10237-471 ndc11 (package): 10237047115 rxcui: 1001084
Zicam Extreme Congestion Relief	OXYMETAZOLINE HYDROCHLORIDE	Church & Dwight Co., Inc.	ccada339-656c-a461-e053-2a95a90a3479	2025-12-31	Warnings	Exact identifier ndc (package): 10237-464-15 ndc (product): 10237-464 ndc11 (package): 10237046415 rxcui: 1001084

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 2 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
ccada339-656c-a461-e053-2a95a90a3479	Zicam Congestion Relief 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Zicam Sinus Relief] [SBD] · Zicam Extreme Congestion Relief 0.05 % Nasal Spray [SY] · Zicam Sinus Relief 0.05 % Nasal Spray [SY] · Zicam Sinus Relief 0.5 MG/ML Nasal Spray [SY]	5	4	Zicam ® Extreme Congestion Relief Nasal Spray	20251231
d916f7ff-84b7-57ef-e053-2995a90a3efa	Zicam Congestion Relief 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Zicam Sinus Relief] [SBD] · Zicam Extreme Congestion Relief 0.05 % Nasal Spray [SY] · Zicam Sinus Relief 0.05 % Nasal Spray [SY] · Zicam Sinus Relief 0.5 MG/ML Nasal Spray [SY]	5	3	Zicam ® Intense Sinus Relief Nasal Spray	20241119

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
d916f7ff-84b7-57ef-e053-2995a90a3efa	Zicam ® Intense Sinus Relief Nasal Spray	Church & Dwight Co., Inc.	20260831
ccada339-656c-a461-e053-2a95a90a3479	Zicam ® Extreme Congestion Relief Nasal Spray	Church & Dwight Co., Inc.	20251231
d916f7ff-84b7-57ef-e053-2995a90a3efa	Zicam ® Intense Sinus Relief Nasal Spray	Church & Dwight Co., Inc.	20241119
954d98e4-af3e-49d6-a1ba-35ef9446d8a8	Zicam ® Sinus Relief	Matrixx Initiatives, Inc. \| Accupac, Inc.	20220127
b02ce199-d5b1-4fb0-81f7-e28656bba642	Zicam ® Extreme Congestion Relief	Matrixx Initiatives, Inc. \| Accupac, Inc.	20220125

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	D11AX	Other dermatologicals	ATC1-4		oxymetazoline
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		oxymetazoline
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		oxymetazoline
ATC	R01AA	Sympathomimetics, plain	ATC1-4		oxymetazoline
FDASPL	D048288	Imidazolines	CHEM	has_chemical_structure	oxymetazoline
FDASPL	N0000192562	Vasoconstrictor	EPC	has_epc	oxymetazoline
FDASPL	N0000175651	Increased Sympathetic Activity	PE	has_pe	oxymetazoline
FDASPL	N0000009908	Vasoconstriction	PE	has_pe	oxymetazoline
MEDRT	D010109	Oxymetazoline	CHEM	has_ingredient	oxymetazoline hydrochloride
MEDRT	D010109	Oxymetazoline	CHEM	has_ingredient	oxymetazoline
MEDRT	D003139	Common Cold	DISEASE	may_treat	oxymetazoline hydrochloride
MEDRT	D003139	Common Cold	DISEASE	may_treat	oxymetazoline
MEDRT	D003231	Conjunctivitis	DISEASE	may_treat	oxymetazoline hydrochloride
MEDRT	D003231	Conjunctivitis	DISEASE	may_treat	oxymetazoline
MEDRT	D012220	Rhinitis	DISEASE	may_treat	oxymetazoline
MEDRT	D012220	Rhinitis	DISEASE	may_treat	oxymetazoline hydrochloride
MEDRT	D012852	Sinusitis	DISEASE	may_treat	oxymetazoline
MEDRT	D012852	Sinusitis	DISEASE	may_treat	oxymetazoline hydrochloride
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	oxymetazoline
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	oxymetazoline hydrochloride
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	oxymetazoline
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	oxymetazoline hydrochloride
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	oxymetazoline
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	oxymetazoline hydrochloride

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Zicam Sinus Relief	rxnav_allrelated
DF	DF	Nasal Spray	rxnav_allrelated
DFG	DFG	Inhalant Product	rxnav_allrelated
DFG	DFG	Nasal Product	rxnav_allrelated
IN	IN	oxymetazoline	rxnav_allrelated
PIN	PIN	oxymetazoline hydrochloride	rxnav_allrelated
SBD	SBD	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Zicam Sinus Relief]	rxnav_allrelated
SBDC	SBDC	oxymetazoline hydrochloride 0.5 MG/ML [Zicam Sinus Relief]	rxnav_allrelated
SBDF	SBDF	oxymetazoline Nasal Spray [Zicam Sinus Relief]	rxnav_allrelated
SBDFP	SBDFP	oxymetazoline hydrochloride Nasal Spray [Zicam Sinus Relief]	rxnav_allrelated
SBDG	SBDG	Zicam Sinus Relief Inhalant Product	rxnav_allrelated
SBDG	SBDG	Zicam Sinus Relief Nasal Product	rxnav_allrelated
SCD	SCD	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray	rxnav_allrelated
SCDC	SCDC	oxymetazoline hydrochloride 0.5 MG/ML	rxnav_allrelated
SCDF	SCDF	oxymetazoline Nasal Spray	rxnav_allrelated
SCDFP	SCDFP	oxymetazoline hydrochloride Nasal Spray	rxnav_allrelated
SCDG	SCDG	oxymetazoline Inhalant Product	rxnav_allrelated
SCDG	SCDG	oxymetazoline Nasal Product	rxnav_allrelated
SCDGP	SCDGP	oxymetazoline hydrochloride Inhalant Product	rxnav_allrelated
SCDGP	SCDGP	oxymetazoline hydrochloride Nasal Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	0.5 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	SINGLE
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
NAMES	Prescribable Synonym	Zicam Congestion Relief 0.05 % Nasal Spray
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Multum MediSource Lexicon