Home RxNorm 1010745 epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution Drug identity information. FDA.report links public drug records from RxNav, DailyMed, FDA NDC, Drugs@FDA, and related public sources where available. This page is informational only and is not medical, prescribing, or regulatory advice.
RxCUI 1010745
RxNorm name epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution
Display name EPINEPHrine/Lidocaine (Injectable)
Full name epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution
Term type SCD
Status Active
Strength 0.005-5 mg/ml
Dose form Sol
Route Injectable
Updated 2026-06-16 07:05:31 RxNorm Status History#
Status Active
Source RXNORM
Current YES
Release start 102010
Active start 102010
Multiple ingredient YES
Branded NO Ingredients And Strength# Derived Ingredient Concepts# FDA NDC Products And Packages# Package NDC, Product NDC, Name table Package NDC Product NDC Name Labeler Application 0404-9886-50 0404-9886 Lidocaine Hydrochloride and Epinephrine Lidocaine Hydrochloride and Epinephrine Henry Schein, Inc. ANDA089635 0409-3177-01 0409-3177 Lidocaine Hydrochloride and Epinephrine LIDOCAINE HYDROCHLORIDE and EPINEPHRINE Hospira, Inc. ANDA089635
Drugs@FDA Applications# Application, NDC, Name table Application NDC Name Marketing category Labeler ANDA089635 0404-9886 Lidocaine Hydrochloride and Epinephrine Lidocaine Hydrochloride and Epinephrine ANDA Henry Schein, Inc.
RxNav Current And Historical NDCs# RxNav current and historical NDC rows page 1 of 1 · 7 matching rows.
NDC11, Source, Active table NDC11 Source Active 00404988650 rxnav_ndcs yes 00409317701 rxnav_ndcs yes 00409317716 rxnav_ndcs yes 00074317701 rxnav_historical 00186014001 rxnav_historical_indirect 52584017701 rxnav_historical 55154237408 rxnav_historical
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Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join Lidocaine Hydrochloride and Epinephrine LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE Henry Schein, Inc. 5569d607-f1cb-4f1d-8a00-d50433ec05d3 2026-05-07 Warnings, Adverse reactions Exact identifier ndc (package): 0404-9886-50 ndc (product): 0404-9886 ndc11 (package): 00404988650 rxcui: 1010745 Xylocaine LIDOCAINE HYDROCHLORIDE, EPINEPHRINE BITARTRATE INJECTION, SOLUTION Henry Schein, Inc 9e8d0318-b2fe-4084-aedf-de97f61605a8 2025-08-07 Warnings, Adverse reactions Exact identifier rxcui: 1010745 Xylocaine LIDOCAINE HYDROCHLORIDE,EPINEPHRINE BITARTRATE Fresenius Kabi USA, LLC ba082c2f-64f4-419d-9c88-74f203316e17 2021-08-25 Warnings, Adverse reactions Exact identifier rxcui: 1010745
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
DailyMed RxNorm Mappings# unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 4 matching rows.
Set ID, RxNorm mappings, Terms table Set ID RxNorm mappings Terms SPL version Label Effective 2f94f711-14c4-48ec-c5a3-c5ec4b8e8729 lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [PSN] · epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [SCD] · epinephrine (as epinephrine bitartrate) 1:200,000 / lidocaine hydrochloride 0.5 % Injectable Solution [SY] · lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [SY] 4 34 These highlights do not include all the information needed to use LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION safely and effectively. See full prescribing information for LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION. LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:100,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration, nerve block, epid 20260504 ba082c2f-64f4-419d-9c88-74f203316e17 lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [PSN] · epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [SCD] · epinephrine (as epinephrine bitartrate) 1:200,000 / lidocaine hydrochloride 0.5 % Injectable Solution [SY] · lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [SY] 4 13 Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP) 20210825 5569d607-f1cb-4f1d-8a00-d50433ec05d3 lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [PSN] · epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [SCD] · epinephrine (as epinephrine bitartrate) 1:200,000 / lidocaine hydrochloride 0.5 % Injectable Solution [SY] · lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [SY] 4 9 These highlights do not include all the information needed to use LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION safely and effectively. See full prescribing information for LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION. LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:100,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration, nerve block, epid 20260507 9e8d0318-b2fe-4084-aedf-de97f61605a8 lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [PSN] · epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [SCD] · epinephrine (as epinephrine bitartrate) 1:200,000 / lidocaine hydrochloride 0.5 % Injectable Solution [SY] · lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution [SY] 4 5 Xylocaine 0.5% (Lidocaine HCl and Epinephrine 1:200,000) 5mg/mL 50mL Multi dose vial 20250807
Recently Linked DailyMed Labels# Set ID, Title, Manufacturer table Set ID Title Manufacturer Effective 2f94f711-14c4-48ec-c5a3-c5ec4b8e8729 These highlights do not include all the information needed to use LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION safely and effectively. See full prescribing information for LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION. LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:100,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration, nerve block, epid Hospira, Inc. 20260917 2f94f711-14c4-48ec-c5a3-c5ec4b8e8729 These highlights do not include all the information needed to use LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION safely and effectively. See full prescribing information for LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION. LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:100,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration, nerve block, epid Hospira, Inc. 20260624 5569d607-f1cb-4f1d-8a00-d50433ec05d3 These highlights do not include all the information needed to use LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION safely and effectively. See full prescribing information for LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION. LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:100,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration, nerve block, epid Henry Schein, Inc. 20260507 2f94f711-14c4-48ec-c5a3-c5ec4b8e8729 These highlights do not include all the information needed to use LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION safely and effectively. See full prescribing information for LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION. LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:100,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration, nerve block, epid Hospira, Inc. 20260504 5569d607-f1cb-4f1d-8a00-d50433ec05d3 Lidocaine HCL 0.5% and Epinephrine 1:200,000 Injection, USP 50 mL Multi Dose Vial Henry Schein, Inc. 20251218 2f94f711-14c4-48ec-c5a3-c5ec4b8e8729 These highlights do not include all the information needed to use LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION safely and effectively. See full prescribing information for LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION. LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:100,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration and nerve block LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE 1:200,000 injection, for infiltration, nerve block, epid Hospira, Inc. 20251208 51d90ac3-ff37-4c56-b996-cfbffbbe713a Lidocaine HCL 0.5% and Epinephrine 1:200,000 Injection, USP 50 mL Multi Dose Vial General Injectables & Vaccines, Inc 20221222 a8145ba7-4c9a-4454-a32d-f28a5fa6fd75 National Council for Prescription Drug Programs 20120724
Drug Classes# Source, Class ID, Class table Source Class ID Class Type Relationship Drug concept ATC C01CA Adrenergic and dopaminergic agents ATC1-4 epinephrine ATC R03AA Alpha- and beta-adrenoreceptor agonists ATC1-4 epinephrine ATC N01BB Amides ATC1-4 lidocaine ATC S02DA Analgesics and anesthetics ATC1-4 lidocaine ATC D04AB Anesthetics for topical use ATC1-4 lidocaine ATC R02AD Anesthetics, local ATC1-4 lidocaine ATC C01BB Antiarrhythmics, class Ib ATC1-4 lidocaine ATC C05AD Local anesthetics ATC1-4 lidocaine ATC S01HA Local anesthetics ATC1-4 lidocaine ATC B02BC Local hemostatics ATC1-4 epinephrine ATC A01AD Other agents for local oral treatment ATC1-4 epinephrine ATC S01EA Sympathomimetics in glaucoma therapy ATC1-4 epinephrine ATC R01AA Sympathomimetics, plain ATC1-4 epinephrine FDASPL D002395 Catecholamines CHEM has_chemical_structure epinephrine FDASPL N0000175552 alpha-Adrenergic Agonist EPC has_epc epinephrine FDASPL N0000175682 Amide Local Anesthetic EPC has_epc lidocaine FDASPL N0000175426 Antiarrhythmic EPC has_epc lidocaine FDASPL N0000175555 beta-Adrenergic Agonist EPC has_epc epinephrine FDASPL N0000175570 Catecholamine EPC has_epc epinephrine FDASPL N0000000209 Adrenergic alpha-Agonists MOA has_moa epinephrine FDASPL N0000000245 Adrenergic beta-Agonists MOA has_moa epinephrine FDASPL N0000175976 Local Anesthesia PE has_pe lidocaine MEDRT D004837 Epinephrine CHEM has_ingredient epinephrine MEDRT D008012 Lidocaine CHEM has_ingredient lidocaine hydrochloride MEDRT D008012 Lidocaine CHEM has_ingredient lidocaine MEDRT D000219 Adams-Stokes Syndrome DISEASE ci_with lidocaine hydrochloride MEDRT D000219 Adams-Stokes Syndrome DISEASE ci_with lidocaine MEDRT D000402 Airway Obstruction DISEASE may_treat epinephrine MEDRT D000707 Anaphylaxis DISEASE may_treat epinephrine MEDRT D001145 Arrhythmias, Cardiac DISEASE ci_with epinephrine MEDRT D001919 Bradycardia DISEASE may_treat epinephrine MEDRT D001986 Bronchial Spasm DISEASE may_treat epinephrine MEDRT D002056 Burns DISEASE may_treat lidocaine MEDRT D002056 Burns DISEASE may_treat lidocaine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with epinephrine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with lidocaine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with lidocaine hydrochloride MEDRT D064420 Drug-Related Side Effects and Adverse Reactions DISEASE may_treat lidocaine hydrochloride MEDRT D064420 Drug-Related Side Effects and Adverse Reactions DISEASE may_treat lidocaine MEDRT D004935 Esophageal Diseases DISEASE may_treat lidocaine MEDRT D004935 Esophageal Diseases DISEASE may_treat lidocaine hydrochloride MEDRT D015812 Glaucoma, Angle-Closure DISEASE ci_with epinephrine MEDRT D005902 Glaucoma, Open-Angle DISEASE may_treat epinephrine MEDRT D006323 Heart Arrest DISEASE may_treat epinephrine MEDRT D006327 Heart Block DISEASE may_treat epinephrine MEDRT D006967 Hypersensitivity DISEASE ci_with lidocaine hydrochloride MEDRT D006967 Hypersensitivity DISEASE ci_with lidocaine MEDRT D007022 Hypotension DISEASE may_treat epinephrine MEDRT D009059 Mouth Diseases DISEASE may_treat lidocaine MEDRT D009059 Mouth Diseases DISEASE may_treat lidocaine hydrochloride MEDRT D009203 Myocardial Infarction DISEASE may_treat lidocaine hydrochloride MEDRT D010146 Pain DISEASE may_prevent lidocaine MEDRT D010146 Pain DISEASE may_prevent lidocaine hydrochloride MEDRT D010146 Pain DISEASE may_treat lidocaine MEDRT D010146 Pain DISEASE may_treat lidocaine hydrochloride MEDRT D012772 Shock, Septic DISEASE may_treat epinephrine MEDRT D013614 Tachycardia, Paroxysmal DISEASE may_treat lidocaine MEDRT D013614 Tachycardia, Paroxysmal DISEASE may_treat lidocaine hydrochloride MEDRT D017180 Tachycardia, Ventricular DISEASE may_treat epinephrine MEDRT D017180 Tachycardia, Ventricular DISEASE may_treat lidocaine hydrochloride MEDRT D017180 Tachycardia, Ventricular DISEASE may_treat lidocaine MEDRT D018754 Ventricular Dysfunction DISEASE may_treat lidocaine hydrochloride MEDRT D014693 Ventricular Fibrillation DISEASE may_treat epinephrine MEDRT D014693 Ventricular Fibrillation DISEASE may_treat lidocaine MEDRT D014693 Ventricular Fibrillation DISEASE may_treat lidocaine hydrochloride MEDRT D018879 Ventricular Premature Complexes DISEASE may_treat lidocaine hydrochloride MEDRT D018879 Ventricular Premature Complexes DISEASE may_treat lidocaine MEDRT N0000000209 Adrenergic alpha-Agonists MOA has_moa epinephrine MEDRT N0000009921 Adrenergic beta1-Agonists MOA has_moa epinephrine MEDRT N0000009922 Adrenergic beta2-Agonists MOA has_moa epinephrine MEDRT N0000000180 Sodium Channel Interactions MOA has_moa lidocaine MEDRT N0000000180 Sodium Channel Interactions MOA has_moa lidocaine hydrochloride MEDRT N0000008298 Arterial Vasoconstriction PE has_pe epinephrine MEDRT N0000008322 Bronchodilation PE has_pe epinephrine MEDRT N0000008330 Cardiac Rhythm Alteration PE has_pe lidocaine MEDRT N0000008330 Cardiac Rhythm Alteration PE has_pe lidocaine hydrochloride MEDRT N0000008472 Decreased Cardiac Muscle Organized Electrical Activity PE has_pe lidocaine hydrochloride MEDRT N0000008472 Decreased Cardiac Muscle Organized Electrical Activity PE has_pe lidocaine MEDRT N0000009944 Decreased Intraocular Aqueous Secretion PE has_pe epinephrine MEDRT N0000008889 Decreased Sensory-Somatic Nervous System Organized Electrical Activity PE has_pe lidocaine MEDRT N0000008889 Decreased Sensory-Somatic Nervous System Organized Electrical Activity PE has_pe lidocaine hydrochloride MEDRT N0000009014 Decreased Uterine Smooth Muscle Contraction or Tone PE has_pe epinephrine MEDRT N0000009070 Hemostasis Alteration PE has_pe epinephrine MEDRT N0000178478 Increased Blood Pressure PE has_pe epinephrine MEDRT N0000175976 Local Anesthesia PE has_pe lidocaine hydrochloride MEDRT N0000175976 Local Anesthesia PE has_pe lidocaine MEDRT N0000009808 Positive Chronotropy PE has_pe epinephrine MEDRT N0000009809 Positive Inotropy PE has_pe epinephrine MEDRT N0000009820 Pupillary Dilation PE has_pe epinephrine
Properties# Category, Property, Value table Category Property Value ATTRIBUTES AVAILABLE_STRENGTH 0.005 MG/ML / 5 MG/ML ATTRIBUTES GENERAL_CARDINALITY MULTI ATTRIBUTES HUMAN_DRUG US ATTRIBUTES RXNAV_HUMAN_DRUG US ATTRIBUTES SCHEDULE 0 CODES ANDA ANDA089635 CODES SNOMEDCT 784975005 CODES VUID 4005916 NAMES Prescribable Synonym lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution NAMES Tallman Synonym EPINEPHrine (as EPINEPHrine bitartrate) 1:200,000 / lidocaine hydrochloride 0.5 % Injectable Solution NAMES Tallman Synonym EPINEPHrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution NAMES Tallman Synonym lidocaine HCl 0.5 % / EPINEPHrine 1:200,000 Injectable Solution SOURCES Source Gold Standard Alchemy SOURCES Source Metathesaurus FDA Structured Product Labels SOURCES Source Micromedex RED BOOK SOURCES Source Multum MediSource Lexicon SOURCES Source National Drug Data File Plus Source Vocabulary SOURCES Source US Edition of SNOMED_CT SOURCES Source Veterans Health Administration National Drug File