FDA.reportPublic FDA data

epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with Epinephrine]

RxCUI
1010749
RxNorm name
epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with Epinephrine]
Display name
XYLOCAINE WITH EPINEPHrine (Injectable)
Full name
epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with Epinephrine]
Term type
SBD
Status
Active
Strength
0.005-5 mg/ml
Dose form
Sol
Route
Injectable
Updated
2026-06-16 07:05:35

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
102010
Active start
102010
Multiple ingredient
YES
Branded
YES

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
epinephrine bitartrate5 MCG / 1 MLepinephrineepinephrine
lidocaine hydrochloride5 MG / 1 MLlidocainelidocaine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Injectable Solution316949

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
epinephrine3992
lidocaine6387

Source Vocabulary Codes#

Code type, Value, Category table
Code typeValueCategory
PRESCRIBABLEYATTRIBUTES
RXNAV_STRXylocaine 0.5 % with EPINEPHrine 1:200,000 Injectable SolutionNAMES
RxNorm Nameepinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with Epinephrine]NAMES
RxNorm SynonymXylocaine 0.5 % with epinephrine 1:200,000 Injectable SolutionNAMES
RxNorm SynonymXylocaine with Epinephrine 0.5/1:200000 (lidocaine hydrochloride / epinephrine (as epinephrine bitartrate) ) Injectable SolutionNAMES
TTYSBDATTRIBUTES
SPL_SET_ID9e8d0318-b2fe-4084-aedf-de97f61605a8CODES
SPL_SET_IDba082c2f-64f4-419d-9c88-74f203316e17CODES
RxCUI1010749CODES
MMSL_CODEBD3779CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
0404-9975-500404-9975Xylocaine Lidocaine hydrochloride, epinephrine bitartrate injection, solutionHenry Schein, IncNDA006488
63323-481-5763323-481Xylocaine LIDOCAINE HYDROCHLORIDE,EPINEPHRINE BITARTRATEFresenius Kabi USA, LLCNDA006488

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
NDA0064880404-9975Xylocaine Lidocaine hydrochloride, epinephrine bitartrate injection, solutionNDAHenry Schein, Inc

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11SourceActive
00404997550rxnav_ndcsyes
63323048101rxnav_ndcsyes
63323048157rxnav_ndcsyes
00186014001rxnav_historical
52584048157rxnav_historical
63323048150rxnav_historical

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set IDRxNorm stringTTYSPL versionLabelEffective
ba082c2f-64f4-419d-9c88-74f203316e17epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with Epinephrine]SBD13Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20210825
ba082c2f-64f4-419d-9c88-74f203316e17Xylocaine 0.5 % / EPINEPHrine 1:200,000 Injectable SolutionPSN13Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20210825
ba082c2f-64f4-419d-9c88-74f203316e17Xylocaine 0.5 % with epinephrine 1:200,000 Injectable SolutionSY13Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20210825
ba082c2f-64f4-419d-9c88-74f203316e17Xylocaine with Epinephrine 0.5/1:200000 (lidocaine hydrochloride / epinephrine (as epinephrine bitartrate) ) Injectable SolutionSY13Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20210825
9e8d0318-b2fe-4084-aedf-de97f61605a8Xylocaine 0.5 % with epinephrine 1:200,000 Injectable SolutionSY5Xylocaine 0.5% (Lidocaine HCl and Epinephrine 1:200,000) 5mg/mL 50mL Multi dose vial20250807
9e8d0318-b2fe-4084-aedf-de97f61605a8Xylocaine 0.5 % / EPINEPHrine 1:200,000 Injectable SolutionPSN5Xylocaine 0.5% (Lidocaine HCl and Epinephrine 1:200,000) 5mg/mL 50mL Multi dose vial20250807
9e8d0318-b2fe-4084-aedf-de97f61605a8Xylocaine with Epinephrine 0.5/1:200000 (lidocaine hydrochloride / epinephrine (as epinephrine bitartrate) ) Injectable SolutionSY5Xylocaine 0.5% (Lidocaine HCl and Epinephrine 1:200,000) 5mg/mL 50mL Multi dose vial20250807
9e8d0318-b2fe-4084-aedf-de97f61605a8epinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with Epinephrine]SBD5Xylocaine 0.5% (Lidocaine HCl and Epinephrine 1:200,000) 5mg/mL 50mL Multi dose vial20250807

DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
9e8d0318-b2fe-4084-aedf-de97f61605a8Xylocaine 0.5% (Lidocaine HCl and Epinephrine 1:200,000) 5mg/mL 50mL Multi dose vialHenry Schein, Inc20250807
ba082c2f-64f4-419d-9c88-74f203316e17Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)Fresenius Kabi USA, LLC | Fresenius Kabi Austria20210825

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCC01CAAdrenergic and dopaminergic agentsATC1-4epinephrine
ATCR03AAAlpha- and beta-adrenoreceptor agonistsATC1-4epinephrine
ATCN01BBAmidesATC1-4lidocaine
ATCS02DAAnalgesics and anestheticsATC1-4lidocaine
ATCD04ABAnesthetics for topical useATC1-4lidocaine
ATCR02ADAnesthetics, localATC1-4lidocaine
ATCC01BBAntiarrhythmics, class IbATC1-4lidocaine
ATCC05ADLocal anestheticsATC1-4lidocaine
ATCS01HALocal anestheticsATC1-4lidocaine
ATCB02BCLocal hemostaticsATC1-4epinephrine
ATCA01ADOther agents for local oral treatmentATC1-4epinephrine
ATCS01EASympathomimetics in glaucoma therapyATC1-4epinephrine
ATCR01AASympathomimetics, plainATC1-4epinephrine
FDASPLD002395CatecholaminesCHEMhas_chemical_structureepinephrine
FDASPLN0000175552alpha-Adrenergic AgonistEPChas_epcepinephrine
FDASPLN0000175682Amide Local AnestheticEPChas_epclidocaine
FDASPLN0000175426AntiarrhythmicEPChas_epclidocaine
FDASPLN0000175555beta-Adrenergic AgonistEPChas_epcepinephrine
FDASPLN0000175570CatecholamineEPChas_epcepinephrine
FDASPLN0000000209Adrenergic alpha-AgonistsMOAhas_moaepinephrine
FDASPLN0000000245Adrenergic beta-AgonistsMOAhas_moaepinephrine
FDASPLN0000175976Local AnesthesiaPEhas_pelidocaine
MEDRTD004837EpinephrineCHEMhas_ingredientepinephrine
MEDRTD008012LidocaineCHEMhas_ingredientlidocaine hydrochloride
MEDRTD008012LidocaineCHEMhas_ingredientlidocaine
MEDRTD000219Adams-Stokes SyndromeDISEASEci_withlidocaine hydrochloride
MEDRTD000219Adams-Stokes SyndromeDISEASEci_withlidocaine
MEDRTD000402Airway ObstructionDISEASEmay_treatepinephrine
MEDRTD000707AnaphylaxisDISEASEmay_treatepinephrine
MEDRTD001145Arrhythmias, CardiacDISEASEci_withepinephrine
MEDRTD001919BradycardiaDISEASEmay_treatepinephrine
MEDRTD001986Bronchial SpasmDISEASEmay_treatepinephrine
MEDRTD002056BurnsDISEASEmay_treatlidocaine
MEDRTD002056BurnsDISEASEmay_treatlidocaine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withepinephrine
MEDRTD004342Drug HypersensitivityDISEASEci_withlidocaine
MEDRTD004342Drug HypersensitivityDISEASEci_withlidocaine hydrochloride
MEDRTD064420Drug-Related Side Effects and Adverse ReactionsDISEASEmay_treatlidocaine hydrochloride
MEDRTD064420Drug-Related Side Effects and Adverse ReactionsDISEASEmay_treatlidocaine
MEDRTD004935Esophageal DiseasesDISEASEmay_treatlidocaine
MEDRTD004935Esophageal DiseasesDISEASEmay_treatlidocaine hydrochloride
MEDRTD015812Glaucoma, Angle-ClosureDISEASEci_withepinephrine
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatepinephrine
MEDRTD006323Heart ArrestDISEASEmay_treatepinephrine
MEDRTD006327Heart BlockDISEASEmay_treatepinephrine
MEDRTD006967HypersensitivityDISEASEci_withlidocaine hydrochloride
MEDRTD006967HypersensitivityDISEASEci_withlidocaine
MEDRTD007022HypotensionDISEASEmay_treatepinephrine
MEDRTD009059Mouth DiseasesDISEASEmay_treatlidocaine
MEDRTD009059Mouth DiseasesDISEASEmay_treatlidocaine hydrochloride
MEDRTD009203Myocardial InfarctionDISEASEmay_treatlidocaine hydrochloride
MEDRTD010146PainDISEASEmay_preventlidocaine
MEDRTD010146PainDISEASEmay_preventlidocaine hydrochloride
MEDRTD010146PainDISEASEmay_treatlidocaine
MEDRTD010146PainDISEASEmay_treatlidocaine hydrochloride
MEDRTD012772Shock, SepticDISEASEmay_treatepinephrine
MEDRTD013614Tachycardia, ParoxysmalDISEASEmay_treatlidocaine
MEDRTD013614Tachycardia, ParoxysmalDISEASEmay_treatlidocaine hydrochloride
MEDRTD017180Tachycardia, VentricularDISEASEmay_treatepinephrine
MEDRTD017180Tachycardia, VentricularDISEASEmay_treatlidocaine hydrochloride
MEDRTD017180Tachycardia, VentricularDISEASEmay_treatlidocaine
MEDRTD018754Ventricular DysfunctionDISEASEmay_treatlidocaine hydrochloride
MEDRTD014693Ventricular FibrillationDISEASEmay_treatepinephrine
MEDRTD014693Ventricular FibrillationDISEASEmay_treatlidocaine
MEDRTD014693Ventricular FibrillationDISEASEmay_treatlidocaine hydrochloride
MEDRTD018879Ventricular Premature ComplexesDISEASEmay_treatlidocaine hydrochloride
MEDRTD018879Ventricular Premature ComplexesDISEASEmay_treatlidocaine
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaepinephrine
MEDRTN0000009921Adrenergic beta1-AgonistsMOAhas_moaepinephrine
MEDRTN0000009922Adrenergic beta2-AgonistsMOAhas_moaepinephrine
MEDRTN0000000180Sodium Channel InteractionsMOAhas_moalidocaine
MEDRTN0000000180Sodium Channel InteractionsMOAhas_moalidocaine hydrochloride
MEDRTN0000008298Arterial VasoconstrictionPEhas_peepinephrine
MEDRTN0000008322BronchodilationPEhas_peepinephrine
MEDRTN0000008330Cardiac Rhythm AlterationPEhas_pelidocaine
MEDRTN0000008330Cardiac Rhythm AlterationPEhas_pelidocaine hydrochloride
MEDRTN0000008472Decreased Cardiac Muscle Organized Electrical ActivityPEhas_pelidocaine hydrochloride
MEDRTN0000008472Decreased Cardiac Muscle Organized Electrical ActivityPEhas_pelidocaine
MEDRTN0000009944Decreased Intraocular Aqueous SecretionPEhas_peepinephrine
MEDRTN0000008889Decreased Sensory-Somatic Nervous System Organized Electrical ActivityPEhas_pelidocaine
MEDRTN0000008889Decreased Sensory-Somatic Nervous System Organized Electrical ActivityPEhas_pelidocaine hydrochloride
MEDRTN0000009014Decreased Uterine Smooth Muscle Contraction or TonePEhas_peepinephrine
MEDRTN0000009070Hemostasis AlterationPEhas_peepinephrine
MEDRTN0000178478Increased Blood PressurePEhas_peepinephrine
MEDRTN0000175976Local AnesthesiaPEhas_pelidocaine hydrochloride
MEDRTN0000175976Local AnesthesiaPEhas_pelidocaine
MEDRTN0000009808Positive ChronotropyPEhas_peepinephrine
MEDRTN0000009809Positive InotropyPEhas_peepinephrine
MEDRTN0000009820Pupillary DilationPEhas_peepinephrine

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH0.005 MG/ML / 5 MG/ML
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESPRESCRIBABLEY
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
ATTRIBUTESTTYSBD
CODESMMSL_CODEBD3779
CODESNDANDA006488
CODESRxCUI1010749
CODESSPL_SET_ID9e8d0318-b2fe-4084-aedf-de97f61605a8
CODESSPL_SET_IDba082c2f-64f4-419d-9c88-74f203316e17
NAMESPrescribable SynonymXylocaine 0.5 % / EPINEPHrine 1:200,000 Injectable Solution
NAMESRXNAV_STRXylocaine 0.5 % with EPINEPHrine 1:200,000 Injectable Solution
NAMESRxNorm Nameepinephrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with Epinephrine]
NAMESRxNorm SynonymXylocaine 0.5 % with epinephrine 1:200,000 Injectable Solution
NAMESRxNorm SynonymXylocaine with Epinephrine 0.5/1:200000 (lidocaine hydrochloride / epinephrine (as epinephrine bitartrate) ) Injectable Solution
NAMESTallman SynonymEPINEPHrine 0.005 MG/ML / lidocaine hydrochloride 5 MG/ML Injectable Solution [Xylocaine with EPINEPHrine]
NAMESTallman SynonymXylocaine 0.5 % with EPINEPHrine 1:200,000 Injectable Solution
NAMESTallman SynonymXylocaine with EPINEPHrine 0.5/1:200000 (lidocaine hydrochloride / EPINEPHrine (as EPINEPHrine bitartrate) ) Injectable Solution
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK
SOURCESSourceMultum MediSource Lexicon