Home RxNorm 1049632 diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] Drug identity information. FDA.report links public drug records from RxNav, DailyMed, FDA NDC, Drugs@FDA, and related public sources where available. This page is informational only and is not medical, prescribing, or regulatory advice.
RxCUI 1049632
RxNorm name diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl]
Display name BENADRYL (Oral Pill)
Full name diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl]
Term type SBD
Status Active
Strength 25 mg
Dose form Tab
Route Oral Pill
Updated 2026-07-24 06:49:46 RxNorm Status History#
Status Active
Source RXNORM
Current YES
Release start 012011
Active start 012011
Multiple ingredient NO
Branded YES Ingredients And Strength# Ingredient, Strength, Base table Ingredient Strength Base Basis of strength diphenhydramine hydrochloride 25 MG / 1 EACH diphenhydramine diphenhydramine hydrochloride
Derived Ingredient Concepts# FDA NDC Products And Packages# Package NDC, Product NDC, Name table Package NDC Product NDC Name Labeler Application 50269-226-54 50269-226 Benadryl Ultra Tab DIPHENHYDRAMINE HYDROCHLORIDE JC World Bell Wholesale Co., Inc. M012 50269-528-00 50269-528 Benadryl Allergy DIPHENHYDRAMINE HYDROCHLORIDE JC World Bell Wholesale Co., Inc. M012 50580-226-12 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-20 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-33 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-50 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-51 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-52 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-53 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-54 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-56 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-62 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-226-70 50580-226 Benadryl Diphenhydramine Hydrochloride Kenvue Brands LLC M012 50580-370-01 50580-370 Benadryl diphenhydramine hydrochloride Kenvue Brands LLC M012 53209-3001-2 53209-3001 Benadryl Diphenhydramine Hydrochloride Morning Star OTC M012 66715-6406-2 66715-6406 Benadryl Diphenhydramine Hydrochloride Lil' Drug Store Products, Inc. M012 66715-6406-7 66715-6406 Benadryl Diphenhydramine Hydrochloride Lil' Drug Store Products, Inc. M012 66715-6406-8 66715-6406 Benadryl Diphenhydramine Hydrochloride Lil' Drug Store Products, Inc. M012 66715-6506-2 66715-6506 Benadryl Diphenhydramine Hydrochloride Lil' Drug Store Products, Inc. M012 66715-9706-2 66715-9706 Benadryl Diphenhydramine Hydrochloride Lil' Drug Store Products, Inc. M012 66715-9706-3 66715-9706 Benadryl Diphenhydramine Hydrochloride Lil' Drug Store Products, Inc. M012 67414-226-00 67414-226 Benadryl Allergy Ultratab DIPHENHYDRAMINE HYDROCHLORIDE Jones Healthcare Group - Packaging Services, Inc M012 67414-226-54 67414-226 Benadryl Allergy Ultratab DIPHENHYDRAMINE HYDROCHLORIDE Jones Healthcare Group - Packaging Services, Inc M012 67751-166-01 67751-166 Benadryl Ultratabs DIPHENHYDRAMINE HYDROCHLORIDE Navajo Manufacturing Company Inc. M012 67751-166-02 67751-166 Benadryl Ultratabs DIPHENHYDRAMINE HYDROCHLORIDE Navajo Manufacturing Company Inc. M012 70264-024-01 70264-024 Benadryl Allergy DIPHENHYDRAMINE HYDROCHLORIDE R J General Corporation M012 71205-521-06 71205-521 Benadryl Diphenhydramine Hydrochloride Proficient Rx LP M012 73097-004-02 73097-004 Benadryl Allergy Ultratab DIPHENHYDRAMINE HYDROCHLORIDE Savings Distributors LLC M012 73097-004-40 73097-004 Benadryl Allergy Ultratab DIPHENHYDRAMINE HYDROCHLORIDE Savings Distributors LLC M012 73097-004-50 73097-004 Benadryl Allergy Ultratab DIPHENHYDRAMINE HYDROCHLORIDE Savings Distributors LLC M012
Drugs@FDA Applications# Application, NDC, Name table Application NDC Name Marketing category Labeler M012 50269-226 Benadryl Ultra Tab DIPHENHYDRAMINE HYDROCHLORIDE OTC MONOGRAPH DRUG JC World Bell Wholesale Co., Inc.
RxNav Current And Historical NDCs# RxNav current and historical NDC rows page 1 of 1 · 74 matching rows.
NDC11, Source, Active table NDC11 Source Active 00045017008 rxnav_ndcs yes 00045017014 rxnav_ndcs yes 12547017031 rxnav_ndcs yes 12547017033 rxnav_ndcs yes 12547017136 rxnav_ndcs yes 50269022654 rxnav_ndcs yes 50269052800 rxnav_ndcs yes 50580022612 rxnav_ndcs yes 50580022620 rxnav_ndcs yes 50580022633 rxnav_ndcs yes 50580022650 rxnav_ndcs yes 50580022651 rxnav_ndcs yes 50580022652 rxnav_ndcs yes 50580022653 rxnav_ndcs yes 50580022654 rxnav_ndcs yes 50580022656 rxnav_ndcs yes 50580022662 rxnav_ndcs yes 50580022670 rxnav_ndcs yes 50580037001 rxnav_ndcs yes 53209300101 rxnav_ndcs yes 53209300102 rxnav_ndcs yes 66715640602 rxnav_ndcs yes 66715640607 rxnav_ndcs yes 66715640608 rxnav_ndcs yes 66715650602 rxnav_ndcs yes 66715970602 rxnav_ndcs yes 66715970603 rxnav_ndcs yes 67414022600 rxnav_ndcs yes 67414022654 rxnav_ndcs yes 67751016601 rxnav_ndcs yes 67751016602 rxnav_ndcs yes 70264002401 rxnav_ndcs yes 71205052106 rxnav_ndcs yes 73097000402 rxnav_ndcs yes 73097000440 rxnav_ndcs yes 73097000450 rxnav_ndcs yes 00045010825 rxnav_historical 00045010849 rxnav_historical 00045022614 rxnav_historical 00045055725 rxnav_historical 00450017014 rxnav_historical 00501200224 rxnav_historical 00501200299 rxnav_historical 00501200914 rxnav_historical 00501200924 rxnav_historical 00501200948 rxnav_historical 00501200999 rxnav_historical 12547017021 rxnav_historical 21695081124 rxnav_historical 29485100704 rxnav_historical 29485650604 rxnav_historical 29485693106 rxnav_historical 29485796302 rxnav_historical 29485796303 rxnav_historical 50580022602 rxnav_historical 50580022603 rxnav_historical 50580022610 rxnav_historical 50580022611 rxnav_historical 50580022614 rxnav_historical 50580022624 rxnav_historical 50580022648 rxnav_historical 50580022655 rxnav_historical 50580058025 rxnav_historical 50580058049 rxnav_historical 52904096004 rxnav_historical 52904096005 rxnav_historical 52904096020 rxnav_historical 52904096025 rxnav_historical 52904096030 rxnav_historical 61786086602 rxnav_historical 61786086636 rxnav_historical 66715970601 rxnav_historical 70518243800 rxnav_historical 76413035324 rxnav_historical
UNII Substances# UNII substance links page 1 of 1 · 0 matching rows.
No records found.
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 12 matching rows.
DailyMed RxNorm Mappings# unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 14 matching rows.
Set ID, RxNorm mappings, Terms table Set ID RxNorm mappings Terms SPL version Label Effective 702f9786-7ce9-43e4-921d-e1db09612127 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 31 Benadryl ® 20260206 de2a64ce-c169-4162-b79e-d3809bea2147 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 10 Benadryl ® 20241122 2884d2dc-2d4a-4ca6-ab73-688a80b428eb Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 10 Benadryl 20241108 ec2070df-8a8a-4cd1-8830-62655433fb3b Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 6 Benadryl Allergy Ultratab 20231105 c46c01c0-29f4-400c-bef5-14b3eb944c51 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 4 Benadryl Allergy 20251117 17633c87-ff0f-4fde-ab23-bc43bdc3fa8e Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 4 Benadryl Ultra Tab 20241231 76433e3c-142c-4704-8b2b-d602f008c377 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 4 Benadryl Ultratabs 20241002 8d59d121-62a8-c43b-e053-2a95a90a5847 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 3 Benadryl Allergy Ultratab 20260501 b1c849e5-8003-4fd3-811d-6a927523e353 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 2 Benadryl ® 20231201 37573ee4-4df8-4909-bbaf-9a7dbe336e8e Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 2 Benadryl ® 20180924 7c8b3e05-bdd5-46d3-8ff4-ea6e1f188549 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 1 Benadryl Allergy 20250903 f4ff84b3-bb0c-4900-8ba4-6d1b90394782 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 1 Benadryl ® 20250609 d3f44425-db82-4569-8ed0-2fe990b23384 Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 1 Benadryl ® 20220330 9c3fc14a-551c-4957-9074-6b27dfd4a29f Benadryl 25 MG Oral Tablet [PSN] · diphenhydramine hydrochloride 25 MG Oral Tablet [Benadryl] [SBD] · Benadryl 25 MG Oral Tablet [SY] · Benadryl Allergy Ultratab 25 MG Oral Tablet [SY] 4 1 Benadryl ® ™ ALLERGY 20110413
Recently Linked DailyMed Labels# Drug Classes# Source, Class ID, Class table Source Class ID Class Type Relationship Drug concept ATC R06AA Aminoalkyl ethers ATC1-4 diphenhydramine ATC D04AA Antihistamines for topical use ATC1-4 diphenhydramine FDASPL N0000175587 Histamine-1 Receptor Antagonist EPC has_epc diphenhydramine FDASPL N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine hydrochloride MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine hydrochloride MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine hydrochloride MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine MEDRT D007774 Lactation DISEASE ci_with diphenhydramine hydrochloride MEDRT D007774 Lactation DISEASE ci_with diphenhydramine MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine hydrochloride MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine MEDRT D009325 Nausea DISEASE may_treat diphenhydramine MEDRT D009325 Nausea DISEASE may_treat diphenhydramine hydrochloride MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine hydrochloride MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine hydrochloride MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine hydrochloride MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine hydrochloride MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine hydrochloride MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine
Properties# Category, Property, Value table Category Property Value ATTRIBUTES AVAILABLE_STRENGTH 25 MG ATTRIBUTES GENERAL_CARDINALITY SINGLE ATTRIBUTES HUMAN_DRUG US ATTRIBUTES RXNAV_HUMAN_DRUG US ATTRIBUTES SCHEDULE 0 NAMES Prescribable Synonym Benadryl 25 MG Oral Tablet NAMES Tallman Synonym diphenhydrAMINE hydrochloride 25 MG Oral Tablet [Benadryl] SOURCES Source Gold Standard Alchemy SOURCES Source Metathesaurus FDA Structured Product Labels SOURCES Source Micromedex RED BOOK SOURCES Source Multum MediSource Lexicon