FDA.reportPublic FDA data

diphenhydramine hydrochloride 20 MG/ML Topical Spray

RxCUI
1050080
RxNorm name
diphenhydramine hydrochloride 20 MG/ML Topical Spray
Display name
diphenhydrAMINE (Topical)
Full name
diphenhydramine hydrochloride 20 MG/ML Topical Spray
Term type
SCD
Status
Active
Strength
2%
Dose form
Spray
Route
Topical
Updated
2026-07-19 06:50:54

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
012011
Active start
012011
Multiple ingredient
NO
Branded
NO

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
diphenhydramine hydrochloride20 MG / 1 MLdiphenhydraminediphenhydramine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Topical Spray346165

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
diphenhydramine3498

Source Vocabulary Codes#

Code type, Values, Count table
Code typeValuesCountCategory
PRESCRIBABLEY1ATTRIBUTES
RXNAV_STRdiphenhydrAMINE hydrochloride 20 MG/ML Topical Spray1NAMES
RxNorm Namediphenhydramine hydrochloride 20 MG/ML Topical Spray1NAMES
RxNorm Synonymdiphenhydramine HCl 2 % Topical Spray1NAMES
TTYSCD1ATTRIBUTES
SPL_SET_ID
4 linked values
4CODES
RxCUI10500801CODES
MMSL_CODE
2 linked values
2CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
42961-218-0142961-218Xpect Extra Strength Itch Relief Diphenhydramine HydrochlorideCintas CorporationM017
61010-8300-161010-8300Itch Relief diphenhydramine hydrochlorideSafetec of America, Inc.M017
79903-217-2579903-217Itch Relief Diphenhydramine HClWal-Mart Stores, Inc.M017
81522-751-2581522-751Itch Relief Diphenhydramine HClFSA Store Inc.M017

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M01742961-218Xpect Extra Strength Itch Relief Diphenhydramine HydrochlorideOTC MONOGRAPH DRUGCintas Corporation

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 12 matching rows.

NDC11, Source, Active table
NDC11SourceActive
42961021801rxnav_ndcsyes
49348036630rxnav_ndcsyes
61010830001rxnav_ndcsyes
79903021725rxnav_ndcsyes
81522075125rxnav_ndcsyes
83926010210rxnav_ndcsyes
12547017004rxnav_historical_indirect
37205033816rxnav_historical
50428422290rxnav_historical
51879016306rxnav_historical
59898081010rxnav_historical
81522072601rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Itch ReliefDIPHENHYDRAMINE HCLWal-Mart Stores, Inc.03feaaef-7401-d464-e063-6294a90a2b2d2026-01-27WarningsExact identifier
ndc (package): 79903-217-25
ndc (product): 79903-217
ndc11 (package): 79903021725
rxcui: 1050080
Itch ReliefDIPHENHYDRAMINE HCLFSA Store Inc.47434af6-0fdd-9615-e063-6394a90ab9e82025-12-31WarningsExact identifier
ndc (package): 81522-751-25
ndc (product): 81522-751
ndc11 (package): 81522075125
rxcui: 1050080
Itch EraserDIPHENHYDRAMINE HCLTender Corporation d/b/a Adventure Ready Brands2204e135-6a23-68a2-e063-6394a90ac0192025-11-18WarningsExact identifier
rxcui: 1050080
Xpect Extra Strength Itch ReliefDIPHENHYDRAMINE HYDROCHLORIDECintas Corporationa373b2c3-5c58-4b64-9358-bdf42dfce08c2025-09-24WarningsExact identifier
ndc (package): 42961-218-01
ndc (product): 42961-218
ndc11 (package): 42961021801
rxcui: 1050080
Itch ReliefDIPHENHYDRAMINE HYDROCHLORIDESafetec of America, Inc.4f4c801b-d894-4fa3-b024-6ca41a5f2a952024-02-04WarningsExact identifier
ndc (package): 61010-8300-1
ndc (product): 61010-8300
ndc11 (package): 61010830001
rxcui: 1050080

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 8 matching rows.

Set ID, RxNorm mappings, Terms table
Set IDRxNorm mappingsTermsSPL versionLabelEffective
03feaaef-7401-d464-e063-6294a90a2b2ddiphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]36Equate Itch Relief Pump Spray20260127
a373b2c3-5c58-4b64-9358-bdf42dfce08cdiphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]34Xpect Extra Strength Itch Relief20250924
92ed55fa-6713-43be-be55-6ba77f052c5ddiphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]34Respond ITCH RELIEF SPRAY Itch Relief Spray20150903
4f4c801b-d894-4fa3-b024-6ca41a5f2a95diphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]3361010-8300, Itch Relief Spray20240204
fdcec01b-e4fe-4440-b6e1-572a13c49661diphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]33Xpect First Aid ITCH RELIEF SPRAY Itch Relief Spray20130513
2204e135-6a23-68a2-e063-6394a90ac019diphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]32Itch Eraser Spray20251118
afd7e738-9cf3-7937-e053-2995a90a55bcdiphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]32The Itch Eraser Spray20230119
47434af6-0fdd-9615-e063-6394a90ab9e8diphenhydrAMINE HCl 2 % Topical Spray [PSN] · diphenhydramine hydrochloride 20 MG/ML Topical Spray [SCD] · diphenhydramine HCl 2 % Topical Spray [SY]31Carring Mill Itch Relief Pump Spray20251231

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
03feaaef-7401-d464-e063-6294a90a2b2dEquate Itch Relief Pump SprayWal-Mart Stores, Inc.20260127
47434af6-0fdd-9615-e063-6394a90ab9e8Carring Mill Itch Relief Pump SprayFSA Store Inc.20251231
03feaaef-7401-d464-e063-6294a90a2b2dEquate Itch Relief Pump SprayWal-Mart Stores, Inc.20251029
a373b2c3-5c58-4b64-9358-bdf42dfce08cXpect Extra Strength Itch ReliefCintas Corporation | Safetec of America, Inc20250924
3cd1933c-6341-50d6-e063-6294a90aca32Carring Mill Itch Relief Pump SprayFSA Store Inc.20250819
03feaaef-7401-d464-e063-6294a90a2b2dEquate Itch Relief Pump SprayWal-Mart Stores, Inc.20241220
4f4c801b-d894-4fa3-b024-6ca41a5f2a9561010-8300, Itch Relief SpraySafetec of America, Inc.20240204
b442ff7f-623b-5cc3-e053-2995a90a3094Tec Laboratories Inc.20221130
98b35828-912c-4d08-b5b2-4829aee85742Itch ReliefWater-Jel Technologies, LLC.20201222
e57ed13d-ed4f-4e74-acbd-bf094246c4c9Itch Relief SprayCardinal Health | Vi-Jon20181207
d25d1c56-a203-4998-ba36-338d663c9ad4National Council for Prescription Drug Programs20120724

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCR06AAAminoalkyl ethersATC1-4diphenhydramine
ATCD04AAAntihistamines for topical useATC1-4diphenhydramine
FDASPLN0000175587Histamine-1 Receptor AntagonistEPChas_epcdiphenhydramine
FDASPLN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine hydrochloride
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007774LactationDISEASEci_withdiphenhydramine
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine hydrochloride
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine hydrochloride
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH20 MG/ML
ATTRIBUTESGENERAL_CARDINALITYSINGLE
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
CODESVUID4002565
NAMESPrescribable SynonymdiphenhydrAMINE HCl 2 % Topical Spray
NAMESTallman SynonymdiphenhydrAMINE HCl 2 % Topical Spray
NAMESTallman SynonymdiphenhydrAMINE hydrochloride 20 MG/ML Topical Spray
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMultum MediSource Lexicon
SOURCESSourceNational Drug Data File Plus Source Vocabulary
SOURCESSourceVeterans Health Administration National Drug File