diphenhydramine hydrochloride 50 MG Oral Tablet
- RxCUI
- 1085945
- RxNorm name
- diphenhydramine hydrochloride 50 MG Oral Tablet
- Display name
- diphenhydrAMINE (Oral Pill)
- Full name
- diphenhydramine hydrochloride 50 MG Oral Tablet
- Term type
- SCD
- Status
- Active
- Strength
- 50 mg
- Dose form
- Tab
- Route
- Oral Pill
- Updated
- 2026-07-22 07:06:29
RxNorm Status History#
- Status
- Active
- Source
- RXNORM
- Current
- YES
- Release start
- 022011
- Active start
- 022011
- Multiple ingredient
- NO
- Branded
- NO
Ingredients And Strength#
| Ingredient | Strength | Base | Basis of strength |
|---|---|---|---|
| diphenhydramine hydrochloride | 50 MG / 1 EACH | diphenhydramine | diphenhydramine hydrochloride |
Dose Form Concepts#
| Dose form | RxCUI |
|---|---|
| Oral Tablet | 317541 |
Derived Ingredient Concepts#
| Ingredient | RxCUI |
|---|---|
| diphenhydramine | 3498 |
Source Vocabulary Codes#
FDA NDC Products And Packages#
| Package NDC | Product NDC | Name | Labeler | Application |
|---|---|---|---|---|
| 0363-1799-08 | 0363-1799 | Allergy Relief Diphenhydramine HCl | Walgreen Company | M012 |
| 15579-828-17 | 15579-828 | Jet-Asleep Double Strength Night Time Sleep Aid DIPHENHYDRAMINE HYDROCHLORIDE | Bell Pharmaceuticals, Inc. | M010 |
| 15579-828-23 | 15579-828 | Jet-Asleep Double Strength Night Time Sleep Aid DIPHENHYDRAMINE HYDROCHLORIDE | Bell Pharmaceuticals, Inc. | M010 |
| 17714-023-50 | 17714-023 | Diphenhydramine Hydrochloride Diphenhydramine Hydrochloride | Advance Pharmaceutical Inc. | part341 |
| 37835-852-50 | 37835-852 | Diphenhydramine HCl Diphenhydramine HCl | Bi-Mart | M010 |
| 46122-829-51 | 46122-829 | Allergy Relief Diphenhydramine HCl | AMERISOURCE BERGEN | M012 |
| 51316-221-08 | 51316-221 | Diphenhydramine HCl Diphenhydramine HCl | CVS Pharmacy, Inc. | M012 |
| 51316-799-08 | 51316-799 | Allergy Relief Diphenhydramine HCl | CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED | M012 |
| 55910-450-12 | 55910-450 | Allergy Relief Diphenhydramine HCl | DOLGENCORP INC | M012 |
| 69452-445-24 | 69452-445 | Allergy Relief Diphenhydramine HCl | BIONPHARMA INC. | M012 |
| 69452-445-77 | 69452-445 | Allergy Relief Diphenhydramine HCl | BIONPHARMA INC. | M012 |
Drugs@FDA Applications#
| Application | NDC | Name | Marketing category | Labeler |
|---|---|---|---|---|
| M012 | 0363-1799 | Allergy Relief Diphenhydramine HCl | OTC MONOGRAPH DRUG | Walgreen Company |
| M010 | 15579-828 | Jet-Asleep Double Strength Night Time Sleep Aid DIPHENHYDRAMINE HYDROCHLORIDE | OTC MONOGRAPH DRUG | Bell Pharmaceuticals, Inc. |
| part341 | 17714-023 | Diphenhydramine Hydrochloride Diphenhydramine Hydrochloride | OTC MONOGRAPH FINAL | Advance Pharmaceutical Inc. |
UNII Substances#
No records found.
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
DailyMed RxNorm Mappings#
| Set ID | RxNorm string | TTY | SPL version | Label | Effective |
|---|---|---|---|---|---|
| e8f6991f-c47a-4d12-934b-04fdf092dac3 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 4 | Sominex Max | 20251023 |
| e8f6991f-c47a-4d12-934b-04fdf092dac3 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 4 | Sominex Max | 20251023 |
| 063517c0-bcb1-46dd-85f1-bbb2f24274ef | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 4 | Somnapure Clinical Strength | 20241206 |
| 063517c0-bcb1-46dd-85f1-bbb2f24274ef | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 4 | Somnapure Clinical Strength | 20241206 |
| dd0a8069-18d8-5696-e053-2995a90a2f22 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 4 | Benadryl ® | 20240906 |
| dd0a8069-18d8-5696-e053-2995a90a2f22 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 4 | Benadryl ® | 20240906 |
| 3c1953a1-32e9-6c81-e063-6294a90a9fa2 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 3 | Diphenhydramine HCl 50 mg tablet, A+ Health, allergy relief dye free | 20260112 |
| 3c1953a1-32e9-6c81-e063-6294a90a9fa2 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 3 | Diphenhydramine HCl 50 mg tablet, A+ Health, allergy relief dye free | 20260112 |
| 7d972559-6184-476b-9cbf-1bc5663ea00d | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 3 | Walgreens 44-799 | 20250602 |
| 7d972559-6184-476b-9cbf-1bc5663ea00d | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 3 | Walgreens 44-799 | 20250602 |
| 4f33c1fb-150b-4083-a9a4-c0fbab4b6133 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | CVS 44-799 | 20260127 |
| 4f33c1fb-150b-4083-a9a4-c0fbab4b6133 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | CVS 44-799 | 20260127 |
| 82d3c489-0ee0-3c79-e053-2a91aa0a2a29 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | 4380- Export | 20240506 |
| 82d3c489-0ee0-3c79-e053-2a91aa0a2a29 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | 4380- Export | 20240506 |
| 16f9b5f4-c116-4f1d-9063-be3abb8ac9ee | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | SleepEze 50 mg Minis_Export only 63029-926-16 | 20240118 |
| 16f9b5f4-c116-4f1d-9063-be3abb8ac9ee | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | SleepEze 50 mg Minis_Export only 63029-926-16 | 20240118 |
| 31d3dcb1-0898-4fee-b236-2f1096b0d787 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | SleepEze Caplet 50 mg_Export only 63029-921 | 20240118 |
| 31d3dcb1-0898-4fee-b236-2f1096b0d787 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | SleepEze Caplet 50 mg_Export only 63029-921 | 20240118 |
| d053201d-9ae2-47c2-8f07-3e4b4af940b6 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | Jet-Asleep Double Strength Night Time Sleep Aid | 20231215 |
| d053201d-9ae2-47c2-8f07-3e4b4af940b6 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | Jet-Asleep Double Strength Night Time Sleep Aid | 20231215 |
| 82fc326a-99bb-9a08-e053-2991aa0a53c2 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | 5344- Export | 20231201 |
| 82fc326a-99bb-9a08-e053-2991aa0a53c2 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | 5344- Export | 20231201 |
| 82e226e6-8bbd-0cd0-e053-2991aa0a9008 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | 4381- Export | 20231130 |
| 82e226e6-8bbd-0cd0-e053-2991aa0a9008 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | 4381- Export | 20231130 |
| 82f8eacb-a234-3080-e053-2a91aa0a6a07 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | 4660- Export | 20231130 |
| 82f8eacb-a234-3080-e053-2a91aa0a6a07 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | 4660- Export | 20231130 |
| 87af0f63-61ea-0d10-e053-2995a90a03c6 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | Nighttime Sleep-Aid Diphenhydramine HCl USP, 50 mg NIGHTTIME SLEEP-AID Rapid Release | 20210129 |
| 87af0f63-61ea-0d10-e053-2995a90a03c6 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | Nighttime Sleep-Aid Diphenhydramine HCl USP, 50 mg NIGHTTIME SLEEP-AID Rapid Release | 20210129 |
| d1f51b7b-da65-4637-8199-f7d59e6dd1c1 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 2 | DIPHENHYDRAMINE HYDROCHLORIDE TABLETS, USP 50mg | 20171030 |
| d1f51b7b-da65-4637-8199-f7d59e6dd1c1 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 2 | DIPHENHYDRAMINE HYDROCHLORIDE TABLETS, USP 50mg | 20171030 |
| 51021c69-d92b-0504-e063-6294a90a94e7 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 1 | Diphenhydramine HCl 50 mg tablet, GNP, allergy relief | 20260504 |
| 51021c69-d92b-0504-e063-6294a90a94e7 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 1 | Diphenhydramine HCl 50 mg tablet, GNP, allergy relief | 20260504 |
| 38400854-27fa-e291-e063-6294a90a5c4e | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 1 | Diphenhydramine HCl 50 mg tablet, Dollar General, allergy relief | 20250623 |
| 38400854-27fa-e291-e063-6294a90a5c4e | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 1 | Diphenhydramine HCl 50 mg tablet, Dollar General, allergy relief | 20250623 |
| b89c80aa-27ae-4fce-b574-8ee64bbae275 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 1 | 20250501 | |
| b89c80aa-27ae-4fce-b574-8ee64bbae275 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 1 | 20250501 | |
| 1059b55b-c218-843f-e063-6294a90af2fe | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 1 | 0110-CVS | 20240201 |
| 1059b55b-c218-843f-e063-6294a90af2fe | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 1 | 0110-CVS | 20240201 |
| 13e2660d-d0a2-4d57-b2de-4c41257ccf83 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 1 | Somnapure Clinical Strength | 20180320 |
| 13e2660d-d0a2-4d57-b2de-4c41257ccf83 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 1 | Somnapure Clinical Strength | 20180320 |
| 8729a4bc-3b63-4b33-a074-26efbb6b089c | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 1 | Somnapure Clinical Strength | 20150526 |
| 8729a4bc-3b63-4b33-a074-26efbb6b089c | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 1 | Somnapure Clinical Strength | 20150526 |
| cddfdbdd-e6d0-49ef-88e7-b5827c665140 | diphenhydrAMINE HCl 50 MG Oral Tablet | PSN | 1 | Somnapure Clinical Strength | 20150409 |
| cddfdbdd-e6d0-49ef-88e7-b5827c665140 | diphenhydramine hydrochloride 50 MG Oral Tablet | SCD | 1 | Somnapure Clinical Strength | 20150409 |
DailyMed Labels#
| Set ID | Title | Manufacturer | Effective |
|---|---|---|---|
| 38400854-27fa-e291-e063-6294a90a5c4e | Diphenhydramine HCl 50 mg tablet, Dollar General, allergy relief | DOLGENCORP INC | Bionpharma Inc. | OrBion Pharmaceuticals Private Limited | JOHNSON & SMITH COMPANY | 20260727 |
| 7d972559-6184-476b-9cbf-1bc5663ea00d | Walgreens 44-799 | Walgreen Company | LNK International, Inc. | 20260630 |
| 3c1953a1-32e9-6c81-e063-6294a90a9fa2 | Diphenhydramine HCl 50 mg tablet, A+ Health, allergy relief dye free | BIONPHARMA INC. | OrBion Pharmaceuticals Private Limited | JOHNSON & SMITH COMPANY | 20260622 |
| 51021c69-d92b-0504-e063-6294a90a94e7 | Diphenhydramine HCl 50 mg tablet, GNP, allergy relief | AMERISOURCE BERGEN | Bionpharma Inc. | OrBion Pharmaceuticals Private Limited | JOHNSON & SMITH COMPANY | 20260622 |
| 51021c69-d92b-0504-e063-6294a90a94e7 | Diphenhydramine HCl 50 mg tablet, GNP, allergy relief | AMERISOURCE BERGEN | Bionpharma Inc. | OrBion Pharmaceuticals Private Limited | 20260504 |
| 4f33c1fb-150b-4083-a9a4-c0fbab4b6133 | CVS 44-799 | CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED | LNK International, Inc. | 20260127 |
| 3c1953a1-32e9-6c81-e063-6294a90a9fa2 | Diphenhydramine HCl 50 mg tablet, A+ Health, allergy relief dye free | BIONPHARMA INC. | OrBion Pharmaceuticals Private Limited | 20260112 |
| 3c1953a1-32e9-6c81-e063-6294a90a9fa2 | Diphenhydramine HCl 50 mg tablet, A+ Health, allergy relief dye free | BIONPHARMA INC. | OrBion Pharmaceuticals Private Limited | 20251208 |
| 38400854-27fa-e291-e063-6294a90a5c4e | Diphenhydramine HCl 50 mg tablet, Dollar General, allergy relief | DOLGENCORP INC | Bionpharma Inc. | OrBion Pharmaceuticals Private Limited | 20250623 |
| 7d972559-6184-476b-9cbf-1bc5663ea00d | Walgreens 44-799 | Walgreen Company | LNK International, Inc. | 20250602 |
| b89c80aa-27ae-4fce-b574-8ee64bbae275 | Bi-Mart | L.N.K. International, Inc. | 20250501 | |
| 1059b55b-c218-843f-e063-6294a90af2fe | 0110-CVS | CVS Pharmacy, Inc. | 20240201 |
| d053201d-9ae2-47c2-8f07-3e4b4af940b6 | Jet-Asleep Double Strength Night Time Sleep Aid | Bell Pharmaceuticals, Inc. | 20231215 |
| ce560b8c-d7d8-4a6c-ad63-dd22a366d1b2 | Walgreens 44-687 | Walgreen Company | LNK International, Inc. | 20210909 |
| 87af0f63-61ea-0d10-e053-2995a90a03c6 | Nighttime Sleep-Aid Diphenhydramine HCl USP, 50 mg NIGHTTIME SLEEP-AID Rapid Release | PHARMACY VALUE ALLIANCE, LLC | 20210129 |
| 85b2e432-14be-42ab-8e30-823a08dc7613 | Drug Facts | TOP CARE (Topco Associates LLC) | 20190801 |
| c9324861-4d26-474e-af32-401cacbc921c | Drug Facts | P & L Development, LLC | 20181221 |
| f11a3a96-9a3f-48b1-b00a-a350a0a6382a | Drug Facts | Hy-Vee | 20181220 |
| 2ffc5822-e0a3-4ff7-904c-c38eb0ef0b6e | Drug Facts | MEIJER, INC. | 20181218 |
| d1f51b7b-da65-4637-8199-f7d59e6dd1c1 | DIPHENHYDRAMINE HYDROCHLORIDE TABLETS, USP 50mg | Advance Pharmaceutical Inc. | 20171030 |
| a228a1cd-1de4-439c-8203-f2888a788581 | National Council for Prescription Drug Programs | 20130213 | |
| 66d3cb86-df2c-443f-9bdd-79995b55d0a4 | Nighttime Sleep Aid | Rugby Laboratories Inc. | Advance Pharmaceutical Inc. | 20121210 |
Drug Classes#
| Source | Class ID | Class | Type | Relationship | Drug concept |
|---|---|---|---|---|---|
| ATC | R06AA | Aminoalkyl ethers | ATC1-4 | diphenhydramine | |
| ATC | D04AA | Antihistamines for topical use | ATC1-4 | diphenhydramine | |
| FDASPL | N0000175587 | Histamine-1 Receptor Antagonist | EPC | has_epc | diphenhydramine |
| FDASPL | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine hydrochloride |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine hydrochloride |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
Properties#
| Category | Property | Value |
|---|---|---|
| ATTRIBUTES | AVAILABLE_STRENGTH | 50 MG |
| ATTRIBUTES | GENERAL_CARDINALITY | SINGLE |
| ATTRIBUTES | HUMAN_DRUG | US |
| ATTRIBUTES | PRESCRIBABLE | Y |
| ATTRIBUTES | RXNAV_HUMAN_DRUG | US |
| ATTRIBUTES | SCHEDULE | 0 |
| ATTRIBUTES | TTY | SCD |
| CODES | MMSL_CODE | BD3425 |
| CODES | MMSL_CODE | CD3425 |
| CODES | RxCUI | 1085945 |
| CODES | SNOMEDCT | 320730006 |
| CODES | SPL_SET_ID | 1059b55b-c218-843f-e063-6294a90af2fe |
| CODES | SPL_SET_ID | 16f9b5f4-c116-4f1d-9063-be3abb8ac9ee |
| CODES | SPL_SET_ID | 31d3dcb1-0898-4fee-b236-2f1096b0d787 |
| CODES | SPL_SET_ID | 38400854-27fa-e291-e063-6294a90a5c4e |
| CODES | SPL_SET_ID | 3c1953a1-32e9-6c81-e063-6294a90a9fa2 |
| CODES | SPL_SET_ID | 4f33c1fb-150b-4083-a9a4-c0fbab4b6133 |
| CODES | SPL_SET_ID | 51021c69-d92b-0504-e063-6294a90a94e7 |
| CODES | SPL_SET_ID | 7d972559-6184-476b-9cbf-1bc5663ea00d |
| CODES | SPL_SET_ID | 82d3c489-0ee0-3c79-e053-2a91aa0a2a29 |
| CODES | SPL_SET_ID | 82e226e6-8bbd-0cd0-e053-2991aa0a9008 |
| CODES | SPL_SET_ID | 82f8eacb-a234-3080-e053-2a91aa0a6a07 |
| CODES | SPL_SET_ID | 82fc326a-99bb-9a08-e053-2991aa0a53c2 |
| CODES | SPL_SET_ID | b89c80aa-27ae-4fce-b574-8ee64bbae275 |
| CODES | SPL_SET_ID | d053201d-9ae2-47c2-8f07-3e4b4af940b6 |
| CODES | SPL_SET_ID | d1f51b7b-da65-4637-8199-f7d59e6dd1c1 |
| CODES | VUID | 4002560 |
| NAMES | Prescribable Synonym | diphenhydrAMINE HCl 50 MG Oral Tablet |
| NAMES | RXNAV_STR | diphenhydrAMINE hydrochloride 50 MG Oral Tablet |
| NAMES | RxNorm Name | diphenhydramine hydrochloride 50 MG Oral Tablet |
| NAMES | Tallman Synonym | diphenhydrAMINE hydrochloride 50 MG Oral Tablet |
| SOURCES | Source | Metathesaurus FDA Structured Product Labels |
| SOURCES | Source | Micromedex RED BOOK |
| SOURCES | Source | Multum MediSource Lexicon |
| SOURCES | Source | National Drug Data File Plus Source Vocabulary |
| SOURCES | Source | US Edition of SNOMED_CT |
| SOURCES | Source | Veterans Health Administration National Drug File |