diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution

RxCUI: 1086720
RxNorm name: diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution
Display name: diphenhydrAMINE/Phenylephrine (Oral Liquid)
Full name: diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution
Term type: SCD
Status: Active
Strength: 12.5-5 mg/5ml
Dose form: Sol
Route: Oral Liquid
Updated: 2026-07-25 06:53:33

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 022011
Active start: 022011
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
diphenhydramine hydrochloride	2.5 MG / 1 ML	diphenhydramine	diphenhydramine hydrochloride
phenylephrine hydrochloride	1 MG / 1 ML	phenylephrine	phenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
diphenhydramine	3498
phenylephrine	8163

Source Vocabulary Codes#

Code type, Value, Category table
Code type	Value	Category
PRESCRIBABLE	Y	ATTRIBUTES
RXNAV_STR	diphenhydrAMINE hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution	NAMES
RxNorm Name	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution	NAMES
RxNorm Synonym	diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 5 ML Oral Solution	NAMES
TTY	SCD	ATTRIBUTES
RxCUI	1086720	CODES
MMSL_CODE	BD24663	CODES
MMSL_CODE	CD24663	CODES

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11	Source	Active
46122031426	rxnav_ndcs	yes
62011025701	rxnav_ndcs	yes
62558000316	rxnav_ndcs	yes
69842029126	rxnav_ndcs	yes
00045055204	rxnav_historical_indirect
00363040904	rxnav_historical
00501242604	rxnav_historical_indirect
11822111901	rxnav_historical
42507004904	rxnav_historical
50580055204	rxnav_historical_indirect
52183038904	rxnav_historical_indirect
62558000118	rxnav_historical
62558000204	rxnav_historical
63824018464	rxnav_historical_indirect
63824018764	rxnav_historical_indirect

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set ID	RxNorm string	TTY	SPL version	Label	Effective
b8b75904-3806-4258-89c1-d6ff486ed41c	diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 5 ML Oral Solution	SY	9	Childrens Benadryl Allergy Plus Congestion	20241108
b8b75904-3806-4258-89c1-d6ff486ed41c	diphenhydrAMINE HCl 12.5 MG / phenylephrine HCl 5 MG in 5 mL Oral Solution	PSN	9	Childrens Benadryl Allergy Plus Congestion	20241108
b8b75904-3806-4258-89c1-d6ff486ed41c	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution	SCD	9	Childrens Benadryl Allergy Plus Congestion	20241108
3ad48c97-16ee-490a-b825-7b4266c0fee8	diphenhydrAMINE HCl 12.5 MG / phenylephrine HCl 5 MG in 5 mL Oral Solution	PSN	2	DRUG LABEL	20200430
3ad48c97-16ee-490a-b825-7b4266c0fee8	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution	SCD	2	DRUG LABEL	20200430
3ad48c97-16ee-490a-b825-7b4266c0fee8	diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 5 ML Oral Solution	SY	2	DRUG LABEL	20200430
7abace52-4d9c-429b-b9a9-96d06261ef50	diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 5 ML Oral Solution	SY	2	Drug Label	20200430
7abace52-4d9c-429b-b9a9-96d06261ef50	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution	SCD	2	Drug Label	20200430
7abace52-4d9c-429b-b9a9-96d06261ef50	diphenhydrAMINE HCl 12.5 MG / phenylephrine HCl 5 MG in 5 mL Oral Solution	PSN	2	Drug Label	20200430
8dcd4966-5cd0-485a-8543-07ebb1247634	diphenhydrAMINE HCl 12.5 MG / phenylephrine HCl 5 MG in 5 mL Oral Solution	PSN	2	Doctor Manzanilla Cough Suppressant and Nasal Decongestant	20150629
8dcd4966-5cd0-485a-8543-07ebb1247634	diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 5 ML Oral Solution	SY	2	Doctor Manzanilla Cough Suppressant and Nasal Decongestant	20150629
8dcd4966-5cd0-485a-8543-07ebb1247634	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution	SCD	2	Doctor Manzanilla Cough Suppressant and Nasal Decongestant	20150629

DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
3ad48c97-16ee-490a-b825-7b4266c0fee8	DRUG LABEL	Mid Valley Pharmaceuticals LLC	20200430
7abace52-4d9c-429b-b9a9-96d06261ef50	Drug Label	Mid Valley Pharmaceuticals LLC	20200430
8dcd4966-5cd0-485a-8543-07ebb1247634	Doctor Manzanilla Cough Suppressant and Nasal Decongestant	Mid Valley Pharmaceuticals LLC	20150629

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		phenylephrine
ATC	R06AA	Aminoalkyl ethers	ATC1-4		diphenhydramine
ATC	D04AA	Antihistamines for topical use	ATC1-4		diphenhydramine
ATC	C05AX	Other agents for treatment of hemorrhoids and anal fissures for topical use	ATC1-4		phenylephrine
ATC	R01BA	Sympathomimetics	ATC1-4		phenylephrine
ATC	S01FB	Sympathomimetics excl. antiglaucoma preparations	ATC1-4		phenylephrine
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		phenylephrine
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		phenylephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		phenylephrine
FDASPL	N0000186105	alpha-1 Adrenergic Agonist	EPC	has_epc	phenylephrine
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	diphenhydramine
FDASPL	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine hydrochloride
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine hydrochloride
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine hydrochloride
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine hydrochloride
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine hydrochloride

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Benadryl-D Allergy and Sinus	rxnav_allrelated
BN	BN	Wal-Dryl PE	rxnav_allrelated
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	diphenhydramine	rxnav_allrelated
IN	IN	phenylephrine	rxnav_allrelated
MIN	MIN	diphenhydramine / phenylephrine	rxnav_allrelated
PIN	PIN	diphenhydramine hydrochloride	rxnav_allrelated
PIN	PIN	phenylephrine hydrochloride	rxnav_allrelated
SBD	SBD	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution [Benadryl-D Allergy and Sinus]	rxnav_allrelated
SBD	SBD	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution [Wal-Dryl PE]	rxnav_allrelated
SBDC	SBDC	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML [Benadryl-D Allergy and Sinus]	rxnav_allrelated
SBDC	SBDC	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML [Wal-Dryl PE]	rxnav_allrelated
SBDF	SBDF	diphenhydramine / phenylephrine Oral Solution [Benadryl-D Allergy and Sinus]	rxnav_allrelated
SBDF	SBDF	diphenhydramine / phenylephrine Oral Solution [Wal-Dryl PE]	rxnav_allrelated
SBDFP	SBDFP	diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution [Benadryl-D Allergy and Sinus]	rxnav_allrelated
SBDFP	SBDFP	diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution [Wal-Dryl PE]	rxnav_allrelated
SBDG	SBDG	Benadryl-D Allergy and Sinus Oral Liquid Product	rxnav_allrelated
SBDG	SBDG	Benadryl-D Allergy and Sinus Oral Product	rxnav_allrelated
SBDG	SBDG	Wal-Dryl PE Oral Liquid Product	rxnav_allrelated
SBDG	SBDG	Wal-Dryl PE Oral Product	rxnav_allrelated
SCD	SCD	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	diphenhydramine hydrochloride 2.5 MG/ML	rxnav_allrelated
SCDC	SCDC	phenylephrine hydrochloride 1 MG/ML	rxnav_allrelated
SCDF	SCDF	diphenhydramine / phenylephrine Oral Solution	rxnav_allrelated
SCDFP	SCDFP	diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution	rxnav_allrelated
SCDG	SCDG	diphenhydramine / phenylephrine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	diphenhydramine / phenylephrine Oral Product	rxnav_allrelated
SCDGP	SCDGP	diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	2.5 MG/ML / 1 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	PRESCRIBABLE	Y
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
ATTRIBUTES	TTY	SCD
CODES	MMSL_CODE	BD24663
CODES	MMSL_CODE	CD24663
CODES	RxCUI	1086720
CODES	VUID	4037802
NAMES	Prescribable Synonym	diphenhydrAMINE HCl 12.5 MG / phenylephrine HCl 5 MG in 5 mL Oral Solution
NAMES	RXNAV_STR	diphenhydrAMINE hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution
NAMES	RxNorm Name	diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution
NAMES	RxNorm Synonym	diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 5 ML Oral Solution
NAMES	Tallman Synonym	diphenhydrAMINE HCl 12.5 MG / phenylephrine HCl 5 MG per 5 ML Oral Solution
NAMES	Tallman Synonym	diphenhydrAMINE hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Micromedex RED BOOK
SOURCES	Source	Multum MediSource Lexicon
SOURCES	Source	National Drug Data File Plus Source Vocabulary
SOURCES	Source	Veterans Health Administration National Drug File

diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution

RxNorm Status History#

Ingredients And Strength#

Dose Form Concepts#

Derived Ingredient Concepts#

Source Vocabulary Codes#

RxNav Current And Historical NDCs#

DailyMed RxNorm Mappings#

DailyMed Labels#

Drug Classes#

Related Concepts#

Properties#