Home RxNorm 1086723 diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution [Benadryl-D Allergy and Sinus] Drug identity information. FDA.report links public drug records from RxNav, DailyMed, FDA NDC, Drugs@FDA, and related public sources where available. This page is informational only and is not medical, prescribing, or regulatory advice.
RxCUI 1086723
RxNorm name diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution [Benadryl-D Allergy and Sinus]
Display name BENADRYL-D ALLERGY AND SINUS (Oral Liquid)
Full name diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution [Benadryl-D Allergy and Sinus]
Term type SBD
Status Active
Strength 12.5-5 mg/5ml
Dose form Sol
Route Oral Liquid
Updated 2026-07-25 06:53:39 RxNorm Status History#
Status Active
Source RXNORM
Current YES
Release start 022011
Active start 022011
Multiple ingredient YES
Branded YES Ingredients And Strength# Derived Ingredient Concepts# FDA NDC Products And Packages# Package NDC, Product NDC, Name table Package NDC Product NDC Name Labeler Application 50580-341-01 50580-341 Childrens Benadryl Allergy Plus Congestion Diphenhydramine hydrochloride and Phenylephrine hydrochloride Kenvue Brands LLC M012
Drugs@FDA Applications# Application, NDC, Name table Application NDC Name Marketing category Labeler M012 50580-341 Childrens Benadryl Allergy Plus Congestion Diphenhydramine hydrochloride and Phenylephrine hydrochloride OTC MONOGRAPH DRUG Kenvue Brands LLC
RxNav Current And Historical NDCs# RxNav current and historical NDC rows page 1 of 1 · 2 matching rows.
NDC11, Source, Active table NDC11 Source Active 50580034101 rxnav_ndcs yes 50580078104 rxnav_historical
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No records found.
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DailyMed RxNorm Mappings# unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 1 matching rows.
Set ID, RxNorm mappings, Terms table Set ID RxNorm mappings Terms SPL version Label Effective b8b75904-3806-4258-89c1-d6ff486ed41c Benadryl-D Children's Allergy & Sinus 12.5 MG / 5 MG in 5 mL Oral Solution [PSN] · diphenhydramine hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution [Benadryl-D Allergy and Sinus] [SBD] · Benadryl Children's Allergy Plus Congestion 12.5 MG / 5 MG per 5 ML Oral Solution [SY] · Benadryl-D Allergy and Sinus (diphenhydramine hydrochloride 12.5 MG/ML / phenylephrine hydrochloride 5 MG) per 5 ML Oral Solution [SY] 4 9 Childrens Benadryl Allergy Plus Congestion 20241108
Recently Linked DailyMed Labels# Drug Classes# Source, Class ID, Class table Source Class ID Class Type Relationship Drug concept ATC C01CA Adrenergic and dopaminergic agents ATC1-4 phenylephrine ATC R06AA Aminoalkyl ethers ATC1-4 diphenhydramine ATC D04AA Antihistamines for topical use ATC1-4 diphenhydramine ATC C05AX Other agents for treatment of hemorrhoids and anal fissures for topical use ATC1-4 phenylephrine ATC R01BA Sympathomimetics ATC1-4 phenylephrine ATC S01FB Sympathomimetics excl. antiglaucoma preparations ATC1-4 phenylephrine ATC S01GA Sympathomimetics used as decongestants ATC1-4 phenylephrine ATC R01AB Sympathomimetics, combinations excl. corticosteroids ATC1-4 phenylephrine ATC R01AA Sympathomimetics, plain ATC1-4 phenylephrine FDASPL N0000186105 alpha-1 Adrenergic Agonist EPC has_epc phenylephrine FDASPL N0000175587 Histamine-1 Receptor Antagonist EPC has_epc diphenhydramine FDASPL N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine hydrochloride MEDRT D010656 Phenylephrine CHEM has_ingredient phenylephrine hydrochloride MEDRT D010656 Phenylephrine CHEM has_ingredient phenylephrine MEDRT D013447 Sulfites CHEM ci_chemclass phenylephrine hydrochloride MEDRT D013447 Sulfites CHEM ci_chemclass phenylephrine MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with phenylephrine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with phenylephrine hydrochloride MEDRT D005401 Fissure in Ano DISEASE may_treat phenylephrine hydrochloride MEDRT D005401 Fissure in Ano DISEASE may_treat phenylephrine MEDRT D005902 Glaucoma, Open-Angle DISEASE may_treat phenylephrine MEDRT D005902 Glaucoma, Open-Angle DISEASE may_treat phenylephrine hydrochloride MEDRT D006484 Hemorrhoids DISEASE may_treat phenylephrine hydrochloride MEDRT D006484 Hemorrhoids DISEASE may_treat phenylephrine MEDRT D006973 Hypertension DISEASE ci_with phenylephrine hydrochloride MEDRT D006973 Hypertension DISEASE ci_with phenylephrine MEDRT D007022 Hypotension DISEASE may_treat phenylephrine hydrochloride MEDRT D007022 Hypotension DISEASE may_treat phenylephrine MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine hydrochloride MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine hydrochloride MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine MEDRT D007774 Lactation DISEASE ci_with diphenhydramine hydrochloride MEDRT D007774 Lactation DISEASE ci_with diphenhydramine MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine hydrochloride MEDRT D015878 Mydriasis DISEASE induces phenylephrine hydrochloride MEDRT D015878 Mydriasis DISEASE induces phenylephrine MEDRT D009325 Nausea DISEASE may_treat diphenhydramine MEDRT D009325 Nausea DISEASE may_treat diphenhydramine hydrochloride MEDRT D011538 Pruritus Ani DISEASE may_treat phenylephrine hydrochloride MEDRT D011538 Pruritus Ani DISEASE may_treat phenylephrine MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine hydrochloride MEDRT D012223 Rhinitis, Vasomotor DISEASE may_treat phenylephrine MEDRT D012223 Rhinitis, Vasomotor DISEASE may_treat phenylephrine hydrochloride MEDRT D012772 Shock, Septic DISEASE may_treat phenylephrine MEDRT D012772 Shock, Septic DISEASE may_treat phenylephrine hydrochloride MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine hydrochloride MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine hydrochloride MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine MEDRT D013617 Tachycardia, Supraventricular DISEASE may_treat phenylephrine hydrochloride MEDRT D013617 Tachycardia, Supraventricular DISEASE may_treat phenylephrine MEDRT D017180 Tachycardia, Ventricular DISEASE ci_with phenylephrine hydrochloride MEDRT D017180 Tachycardia, Ventricular DISEASE ci_with phenylephrine MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine hydrochloride MEDRT N0000000209 Adrenergic alpha-Agonists MOA has_moa phenylephrine hydrochloride MEDRT N0000000209 Adrenergic alpha-Agonists MOA has_moa phenylephrine MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine hydrochloride MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine MEDRT N0000008371 Conjunctival Arterial Vasoconstriction PE has_pe phenylephrine MEDRT N0000008371 Conjunctival Arterial Vasoconstriction PE has_pe phenylephrine hydrochloride MEDRT N0000008896 Decreased Nasal and Sinus Secretions PE has_pe phenylephrine MEDRT N0000008896 Decreased Nasal and Sinus Secretions PE has_pe phenylephrine hydrochloride
Properties# Category, Property, Value table Category Property Value ATTRIBUTES AVAILABLE_STRENGTH 2.5 MG/ML / 1 MG/ML ATTRIBUTES GENERAL_CARDINALITY MULTI ATTRIBUTES HUMAN_DRUG US ATTRIBUTES RXNAV_HUMAN_DRUG US NAMES Prescribable Synonym Benadryl-D Children's Allergy & Sinus 12.5 MG / 5 MG in 5 mL Oral Solution NAMES Tallman Synonym Benadryl-D Allergy and Sinus (diphenhydrAMINE hydrochloride 12.5 MG/ML / phenylephrine hydrochloride 5 MG) per 5 ML Oral Solution NAMES Tallman Synonym diphenhydrAMINE hydrochloride 2.5 MG/ML / phenylephrine hydrochloride 1 MG/ML Oral Solution [Benadryl-D Allergy and Sinus] SOURCES Source Gold Standard Alchemy SOURCES Source Metathesaurus FDA Structured Product Labels SOURCES Source Micromedex RED BOOK