FDA.reportPublic FDA data

diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping]

RxCUI
1111764
RxNorm name
diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping]
Display name
BENADRYL ITCH STOPPING (Topical)
Full name
diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping]
Term type
SBD
Status
Active
Strength
2-0.1%
Dose form
Cream
Route
Topical
Updated
2026-07-19 06:51:32

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
072011
Active start
072011
Multiple ingredient
YES
Branded
YES

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
diphenhydramine hydrochloride20 MG / 1 MLdiphenhydraminediphenhydramine hydrochloride
zinc acetate1 MG / 1 MLzinc acetatezinc acetate

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Topical Cream316982

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
diphenhydramine3498
zinc acetate58295

Source Vocabulary Codes#

Code type, Values, Count table
Code typeValuesCountCategory
PRESCRIBABLEY1ATTRIBUTES
RXNAV_STRBenadryl Itch Stopping, Extra Strength (diphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % ) Topical Cream1NAMES
RxNorm Namediphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping]1NAMES
RxNorm SynonymBenadryl Itch Stopping, Extra Strength (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Cream1NAMES
TTYSBD1ATTRIBUTES
SPL_SET_ID
3 linked values
3CODES
RxCUI11117641CODES
MMSL_CODEBD113611CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
69968-0223-169968-0223Benadryl Extra Strength Diphenhydramine Hydrochloride and Zinc AcetateKenvue Brands LLCM017
69968-0223-269968-0223Benadryl Extra Strength Diphenhydramine Hydrochloride and Zinc AcetateKenvue Brands LLCM017

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M01769968-0223Benadryl Extra Strength Diphenhydramine Hydrochloride and Zinc AcetateOTC MONOGRAPH DRUGKenvue Brands LLC

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 6 matching rows.

NDC11, Source, Active table
NDC11SourceActive
00501320101rxnav_ndcsyes
69968022301rxnav_ndcsyes
69968022302rxnav_ndcsyes
12547017167rxnav_historical
58232074101rxnav_historical
58232074102rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Johnson and Johnson All Purpose First Aid KitACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE, NEOMYCIN SULFATE, POLYMYXIN B SULFATE, AND PRAMOXINE HYDROCHLORIDEKenvue Brands LLC5cdb47c5-7951-4279-8a05-0a3199d3dd452025-11-06WarningsExact identifier
ndc (package): 69968-0223-1
ndc11 (package): 69968022301
rxcui: 1111764
Johnson and Johnson First Aid All Purpose 160 CTACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE, NEOMYCIN SULFATE, POLYMYXIN B SULFATE, AND PRAMOXINE HYDROCHLORIDEKenvue Brands LLCf3933330-2550-4a88-e053-2a95a90a39972025-11-06WarningsExact identifier
ndc (package): 69968-0223-1
ndc11 (package): 69968022301
rxcui: 1111764
Benadryl Extra Strength Itch StoppingDIPHENHYDRAMINE HYDROCHLORIDE AND ZINC ACETATEKenvue Brands LLCa1c1b878-d58f-41ff-b7a8-477f28c526672024-11-12WarningsExact identifier
ndc (package): 69968-0223-1
ndc (package): 69968-0223-2
ndc (product): 69968-0223
ndc11 (package): 69968022301
ndc11 (package): 69968022302
rxcui: 1111764

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 3 matching rows.

Set ID, RxNorm mappings, Terms table
Set IDRxNorm mappingsTermsSPL versionLabelEffective
a1c1b878-d58f-41ff-b7a8-477f28c52667Benadryl Itch Stopping, Extra Strength 2 % / 0.1 % Topical Cream [PSN] · diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping] [SBD] · Benadryl Itch Stopping, Extra Strength (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Cream [SY]310Benadryl ® EXTRA STRENGTH ITCH STOPPING CREAM20241112
5cdb47c5-7951-4279-8a05-0a3199d3dd45Benadryl Itch Stopping, Extra Strength 2 % / 0.1 % Topical Cream [PSN] · diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping] [SBD] · Benadryl Itch Stopping, Extra Strength (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Cream [SY]37Johnson and Johnson All Purpose First Aid Kit20251106
f3933330-2550-4a88-e053-2a95a90a3997Benadryl Itch Stopping, Extra Strength 2 % / 0.1 % Topical Cream [PSN] · diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping] [SBD] · Benadryl Itch Stopping, Extra Strength (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Cream [SY]33Johnson and Johnson First Aid Kit All Purpose 160 CT20251106

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
5cdb47c5-7951-4279-8a05-0a3199d3dd45Johnson and Johnson All Purpose First Aid KitKenvue Brands LLC20251106
f3933330-2550-4a88-e053-2a95a90a3997Johnson and Johnson First Aid Kit All Purpose 160 CTKenvue Brands LLC20251106
f3933330-2550-4a88-e053-2a95a90a3997Johnson and Johnson First Aid Kit All Purpose 160 CTKenvue Brands LLC20241115
a1c1b878-d58f-41ff-b7a8-477f28c52667Benadryl ® EXTRA STRENGTH ITCH STOPPING CREAMKenvue Brands LLC20241112
5cdb47c5-7951-4279-8a05-0a3199d3dd45Johnson and Johnson All Purpose First Aid KitKenvue Brands LLC20240924

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCR06AAAminoalkyl ethersATC1-4diphenhydramine
ATCD04AAAntihistamines for topical useATC1-4diphenhydramine
ATCA16AXVarious alimentary tract and metabolism productsATC1-4zinc acetate
FDASPLN0000175587Histamine-1 Receptor AntagonistEPChas_epcdiphenhydramine
FDASPLN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine hydrochloride
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine
MEDRTD019345Zinc AcetateCHEMhas_ingredientzinc acetate
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine
MEDRTD003139Common ColdDISEASEmay_treatzinc acetate
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine hydrochloride
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012883Skin UlcerDISEASEmay_treatzinc acetate
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD014947Wounds and InjuriesDISEASEmay_treatzinc acetate
MEDRTN0000000226Acid-Base ActivityMOAhas_moazinc acetate
MEDRTN0000000220Electrolyte ActivityMOAhas_moazinc acetate
MEDRTN0000000163Enzyme InteractionsMOAhas_moazinc acetate
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine hydrochloride

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH20 MG/ML / 1 MG/ML
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
NAMESPrescribable SynonymBenadryl Itch Stopping, Extra Strength 2 % / 0.1 % Topical Cream
NAMESTallman SynonymBenadryl Itch Stopping, Extra Strength (diphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % ) Topical Cream
NAMESTallman SynonymdiphenhydrAMINE hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream [Benadryl Itch Stopping]
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK
SOURCESSourceMultum MediSource Lexicon