acetaminophen 250 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Effervescent Oral Tablet

RxCUI: 1536931
RxNorm name: acetaminophen 250 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Effervescent Oral Tablet
Term type: SCD
Status: Active
Updated: 2026-09-25 04:21:38

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 062014
Active start: 062014
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	250 MG / 1 EACH	acetaminophen	acetaminophen
chlorpheniramine maleate	2 MG / 1 EACH	chlorpheniramine	chlorpheniramine maleate
phenylephrine hydrochloride	5 MG / 1 EACH	phenylephrine	phenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Effervescent Oral Tablet	1535727

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
chlorpheniramine	2400
phenylephrine	8163

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
RXNAV_STR	acetaminophen 250 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Effervescent Oral Tablet	1	NAMES
RxNorm Name	acetaminophen 250 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Effervescent Oral Tablet	1	NAMES
RxNorm Synonym	APAP 250 MG / Chlorpheniramine Maleate 2 MG / Phenylephrine Hydrochloride 5 MG Effervescent Oral Tablet	1	NAMES
TTY	SCD	1	ATTRIBUTES
RxCUI	1536931	1	CODES
MMSL_CODE	CD8573	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 6 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
37205021860	rxnav_historical_indirect
41163087060	rxnav_historical
41163087068	rxnav_historical
46122006360	rxnav_historical
46122063660	rxnav_historical
49035087068	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 0 matching rows.

No records found.

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
68a6518f-8143-2bcd-e053-2a91aa0a2256	Good Neighbor Pharmacy Effervescent Cold Relief Plus	Amerisource Bergen Corporation (Good Neighbor Pharmacy)	20201123
f34038cf-eeee-4dfd-a316-a39d85ee6123		National Council for Prescription Drug Programs	20130213
e6929f35-22e3-45b6-9ae8-5cea27467ac7	Drug Facts	Cardinal Health, Inc \| United Exchange Corporation \| Tower Laboratories Ltd	20120914

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		phenylephrine
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	C05AX	Other agents for treatment of hemorrhoids and anal fissures for topical use	ATC1-4		phenylephrine
ATC	R06AB	Substituted alkylamines	ATC1-4		chlorpheniramine
ATC	R01BA	Sympathomimetics	ATC1-4		phenylephrine
ATC	S01FB	Sympathomimetics excl. antiglaucoma preparations	ATC1-4		phenylephrine
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		phenylephrine
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		phenylephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		phenylephrine
FDASPL	N0000186105	alpha-1 Adrenergic Agonist	EPC	has_epc	phenylephrine
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	chlorpheniramine
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine maleate
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine hydrochloride
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine maleate
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine maleate
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Effervescent Oral Tablet	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	chlorpheniramine	rxnav_allrelated
IN	IN	phenylephrine	rxnav_allrelated
MIN	MIN	acetaminophen / chlorpheniramine / phenylephrine	rxnav_allrelated
PIN	PIN	chlorpheniramine maleate	rxnav_allrelated
PIN	PIN	phenylephrine hydrochloride	rxnav_allrelated
SCD	SCD	acetaminophen 250 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Effervescent Oral Tablet	rxnav_allrelated
SCDC	SCDC	acetaminophen 250 MG	rxnav_allrelated
SCDC	SCDC	chlorpheniramine maleate 2 MG	rxnav_allrelated
SCDC	SCDC	phenylephrine hydrochloride 5 MG	rxnav_allrelated
SCDF	SCDF	acetaminophen / chlorpheniramine / phenylephrine Effervescent Oral Tablet	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Effervescent Oral Tablet	rxnav_allrelated
SCDG	SCDG	acetaminophen / chlorpheniramine / phenylephrine Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	250 MG / 2 MG / 5 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
NAMES	Prescribable Synonym	acetaminophen 250 MG / chlorpheniramine maleate 2 MG / phenylephrine HCl 5 MG Effervescent Oral Tablet
SOURCES	Source	Gold Standard Alchemy