sacubitril 49 MG / valsartan 51 MG Oral Tablet

RxCUI: 1656349
RxNorm name: sacubitril 49 MG / valsartan 51 MG Oral Tablet
Display name: Sacubitril/Valsartan (Oral Pill)
Full name: sacubitril 49 MG / valsartan 51 MG Oral Tablet
Term type: SCD
Status: Active
Strength: 49-51 mg
Dose form: Tab
Route: Oral Pill
Updated: 2026-10-29 07:11:10

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 082015
Active start: 082015
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
sacubitril	49 MG / 1 EACH	sacubitril	sacubitril
valsartan	51 MG / 1 EACH	valsartan	valsartan

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Tablet	317541

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
sacubitril	1656328
valsartan	69749

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	sacubitril 49 MG / valsartan 51 MG Oral Tablet	1	NAMES
RxNorm Name	sacubitril 49 MG / valsartan 51 MG Oral Tablet	1	NAMES
TTY	SCD	1	ATTRIBUTES
SPL_SET_ID	29 linked values 2c39c326-34a2-b7f4-e063-6294a90a6732 3cf9da3f-42b7-df11-e063-6294a90ad40b 4c871c01-0564-411f-87e2-478aa42503cf 4ed0dbe4-8752-43c5-8c28-17c9638a52d6 4f88efbb-3718-43a1-91d4-da5943ccfca1 7de9b8e0-195a-b59e-7bbf-3e95c4096af9 43bcdbc7-a635-bb4e-e063-6294a90a990f 44db8114-622e-41f6-96a1-447d47b0267c 59b7a07a-96ee-44b1-8dae-2b42169aa2c5 064a7c51-de30-4759-8210-e18438e6a187 65a3e298-279d-4498-a7be-5f9ee5bc77d8 76cbb87b-6356-4ead-af7f-faffb6e79743 98d838f6-03a9-43e9-b8dd-8882c6df1631 103c39e2-f3c8-40fc-a57e-3af018fb4af4 747eeb5c-ac2f-474f-b6d2-0586d12653a6 998db1e1-3f32-4812-a64b-5a6870ef7f8f 3173e592-6f28-4864-9bf0-0ef0452da3de 4114a976-2e58-8437-e063-6394a90af298 5928f174-83e5-4c74-b15a-138338a70295 8290ae4c-0d1e-47f6-8029-ddc1c0bd6f6d 48714b95-b4ac-ef3c-e063-6294a90a9a5b a0f23b69-5a1b-4aa8-8f0c-5818bd609492 a1fa7066-8ab4-47e3-a701-6c5170700d11 b47b5c7e-1c20-429c-9560-07f5f06cdce3 d85015d5-f619-4a58-b6ab-5e39af3f79d8 e4011f11-2035-4f32-8df6-b1580c2a6e2a e4716fc9-5f73-4303-8a4e-e8f9129b6e2d f2cba3db-0256-422a-a8a4-7afb3a9970d0 f4789255-b59b-544b-bbbe-2edd07da6079	29	CODES
RxCUI	1656349	1	CODES
MMSL_CODE	2 linked values BD30339 CD30339	2	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
0904-7582-04	0904-7582	Sacubitril and Valsartan Sacubitril and Valsartan	Major Pharmaceuticals	ANDA213764
13668-635-05	13668-635	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
13668-635-33	13668-635	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
13668-635-60	13668-635	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
13668-635-74	13668-635	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
13668-746-05	13668-746	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
13668-746-33	13668-746	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
13668-746-60	13668-746	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
13668-746-74	13668-746	sacubitril and valsartan sacubitril and valsartan	Torrent Pharmaceuticals Limited	ANDA213604
31722-674-18	31722-674	Sacubitril and valsartan Sacubitril and valsartan	Camber Pharmaceuticals, Inc.	ANDA213668
31722-674-60	31722-674	Sacubitril and valsartan Sacubitril and valsartan	Camber Pharmaceuticals, Inc.	ANDA213668
33342-571-09	33342-571	Sacubitril and Valsartan Sacubitril and Valsartan	Macleods Pharmaceuticals Limited	ANDA213728
33342-571-57	33342-571	Sacubitril and Valsartan Sacubitril and Valsartan	Macleods Pharmaceuticals Limited	ANDA213728
42385-931-18	42385-931	Sacubitril and Valsartan Sacubitril and Valsartan	Laurus Labs Limited	ANDA213676
42385-931-30	42385-931	Sacubitril and Valsartan Sacubitril and Valsartan	Laurus Labs Limited	ANDA213676
42385-931-60	42385-931	Sacubitril and Valsartan Sacubitril and Valsartan	Laurus Labs Limited	ANDA213676
42385-931-68	42385-931	Sacubitril and Valsartan Sacubitril and Valsartan	Laurus Labs Limited	ANDA213676
42385-931-72	42385-931	Sacubitril and Valsartan Sacubitril and Valsartan	Laurus Labs Limited	ANDA213676
43598-644-18	43598-644	Sacubitril and Valsartan Sacubitril and Valsartan	Dr. Reddy's Laboratories Inc.	ANDA213627
43598-644-60	43598-644	Sacubitril and Valsartan Sacubitril and Valsartan	Dr. Reddy's Laboratories Inc.	ANDA213627
46708-557-10	46708-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Limited	ANDA213682
46708-557-45	46708-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Limited	ANDA213682
46708-557-60	46708-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Limited	ANDA213682
46708-557-91	46708-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Limited	ANDA213682
50268-607-15	50268-607	Sacubitril and Valsartan Sacubitril and Valsartan	AvPAK	ANDA213748
51407-936-10	51407-936	sacubitril and valsartan sacubitril and valsartan	Golden State Medical Supply, Inc.	ANDA213682
60290-086-01	60290-086	Sacubitril and Valsartan Sacubitril and Valsartan	Umedica Laboratories USA Inc.	ANDA219946
60290-086-02	60290-086	Sacubitril and Valsartan Sacubitril and Valsartan	Umedica Laboratories USA Inc.	ANDA219946
60290-086-03	60290-086	Sacubitril and Valsartan Sacubitril and Valsartan	Umedica Laboratories USA Inc.	ANDA219946
60687-966-57	60687-966	Sacubitril and Valsartan Sacubitril and Valsartan	American Health Packaging	ANDA213611
62332-557-10	62332-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Inc.	ANDA213682
62332-557-45	62332-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Inc.	ANDA213682
62332-557-60	62332-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Inc.	ANDA213682
62332-557-91	62332-557	sacubitril and valsartan sacubitril and valsartan	Alembic Pharmaceuticals Inc.	ANDA213682
67877-708-51	67877-708	Sacubitril and Valsartan Sacubitril and Valsartan	Ascend Laboratories, LLC	ANDA213764
67877-708-60	67877-708	Sacubitril and Valsartan Sacubitril and Valsartan	Ascend Laboratories, LLC	ANDA213764
67877-949-33	67877-949	Sacubitril and Valsartan Sacubitril and Valsartan	Ascend Laboratories, LLC	ANDA213764
67877-949-51	67877-949	Sacubitril and Valsartan Sacubitril and Valsartan	Ascend Laboratories, LLC	ANDA213764
67877-949-60	67877-949	Sacubitril and Valsartan Sacubitril and Valsartan	Ascend Laboratories, LLC	ANDA213764
69238-2732-1	69238-2732	Sacubitril and Valsartan Sacubitril and Valsartan	Amneal Pharmaceuticals NY LLC	ANDA213605
69238-2732-2	69238-2732	Sacubitril and Valsartan Sacubitril and Valsartan	Amneal Pharmaceuticals NY LLC	ANDA213605
70069-854-60	70069-854	Sacubitril and Valsartan Sacubitril and Valsartan	Somerset Therapeutics, LLC	ANDA219983
70069-854-80	70069-854	Sacubitril and Valsartan Sacubitril and Valsartan	Somerset Therapeutics, LLC	ANDA219983
70377-032-11	70377-032	Sacubitril and Valsartan Sacubitril and Valsartan	Biocon Pharma Inc.	ANDA213680
70377-032-12	70377-032	Sacubitril and Valsartan Sacubitril and Valsartan	Biocon Pharma Inc.	ANDA213680
70377-032-13	70377-032	Sacubitril and Valsartan Sacubitril and Valsartan	Biocon Pharma Inc.	ANDA213680
70377-032-14	70377-032	Sacubitril and Valsartan Sacubitril and Valsartan	Biocon Pharma Inc.	ANDA213680
70710-1273-4	70710-1273	sacubitril and valsartan sacubitril and valsartan	Zydus Pharmaceuticals USA Inc.	ANDA213719
70710-1273-6	70710-1273	sacubitril and valsartan sacubitril and valsartan	Zydus Pharmaceuticals USA Inc.	ANDA213719
70710-1273-8	70710-1273	sacubitril and valsartan sacubitril and valsartan	Zydus Pharmaceuticals USA Inc.	ANDA213719
70748-196-07	70748-196	sacubitril and valsartan sacubitril and valsartan	Lupin Pharmaceuticals, Inc.	ANDA213808
70771-1922-4	70771-1922	sacubitril and valsartan sacubitril and valsartan	Zydus Lifesciences Limited	ANDA213719
70771-1922-6	70771-1922	sacubitril and valsartan sacubitril and valsartan	Zydus Lifesciences Limited	ANDA213719
70771-1922-8	70771-1922	sacubitril and valsartan sacubitril and valsartan	Zydus Lifesciences Limited	ANDA213719
70954-976-20	70954-976	Sacubitril and Valsartan Sacubitril and Valsartan	ANI Pharmaceuticals, Inc.	ANDA213676
70954-976-30	70954-976	Sacubitril and Valsartan Sacubitril and Valsartan	ANI Pharmaceuticals, Inc.	ANDA213676
70954-976-50	70954-976	Sacubitril and Valsartan Sacubitril and Valsartan	ANI Pharmaceuticals, Inc.	ANDA213676
71610-939-32	71610-939	Sacubitril and Valsartan Sacubitril and Valsartan	Aphena Pharma Solutions - Tennessee, LLC	ANDA213748
71610-939-89	71610-939	Sacubitril and Valsartan Sacubitril and Valsartan	Aphena Pharma Solutions - Tennessee, LLC	ANDA213748
71610-982-89	71610-982	Sacubitril and Valsartan Sacubitril and Valsartan	Aphena Pharma Solutions - Tennessee, LLC	ANDA213728
72205-281-18	72205-281	Sacubitril and Valsartan Sacubitril and Valsartan	Novadoz Pharmaceuticals LLC	ANDA213748
72205-281-60	72205-281	Sacubitril and Valsartan Sacubitril and Valsartan	Novadoz Pharmaceuticals LLC	ANDA213748
72603-881-01	72603-881	Sacubitril and Valsartan Sacubitril and Valsartan	NorthStar RxLLC	ANDA213728
72603-881-02	72603-881	Sacubitril and Valsartan Sacubitril and Valsartan	NorthStar RxLLC	ANDA213728
72865-311-10	72865-311	Sacubitril and Valsartan Sacubitril and Valsartan	XLCare Pharmaceuticals Inc	ANDA213728
72865-311-18	72865-311	Sacubitril and Valsartan Sacubitril and Valsartan	XLCare Pharmaceuticals Inc	ANDA213728
72865-311-60	72865-311	Sacubitril and Valsartan Sacubitril and Valsartan	XLCare Pharmaceuticals Inc	ANDA213728
73190-006-10	73190-006	Sacubitril and Valsartan Sacubitril and Valsartan	AvKARE	ANDA213748
73190-006-18	73190-006	Sacubitril and Valsartan Sacubitril and Valsartan	AvKARE	ANDA213748
73190-006-60	73190-006	Sacubitril and Valsartan Sacubitril and Valsartan	AvKARE	ANDA213748
73190-018-18	73190-018	Sacubitril and Valsartan Sacubitril and Valsartan	AvKARE	ANDA213605
73190-018-60	73190-018	Sacubitril and Valsartan Sacubitril and Valsartan	AvKARE	ANDA213605
82293-028-10	82293-028	Sacubitril and Valsartan Sacubitril and Valsartan	Novugen Pharma (USA) LLC	ANDA213611
82293-028-20	82293-028	Sacubitril and Valsartan Sacubitril and Valsartan	Novugen Pharma (USA) LLC	ANDA213611
82293-028-30	82293-028	Sacubitril and Valsartan Sacubitril and Valsartan	Novugen Pharma (USA) LLC	ANDA213611

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
ANDA213764	0904-7582	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Major Pharmaceuticals
ANDA213604	13668-635	sacubitril and valsartan sacubitril and valsartan	ANDA	Torrent Pharmaceuticals Limited
ANDA213668	31722-674	Sacubitril and valsartan Sacubitril and valsartan	ANDA	Camber Pharmaceuticals, Inc.
ANDA213728	33342-571	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Macleods Pharmaceuticals Limited
ANDA213676	42385-931	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Laurus Labs Limited
ANDA213627	43598-644	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Dr. Reddy's Laboratories Inc.
ANDA213682	46708-557	sacubitril and valsartan sacubitril and valsartan	ANDA	Alembic Pharmaceuticals Limited
ANDA213748	50268-607	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	AvPAK
ANDA219946	60290-086	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Umedica Laboratories USA Inc.
ANDA213611	60687-966	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	American Health Packaging
ANDA213605	69238-2732	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Amneal Pharmaceuticals NY LLC
ANDA219983	70069-854	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Somerset Therapeutics, LLC
ANDA213680	70377-032	Sacubitril and Valsartan Sacubitril and Valsartan	ANDA	Biocon Pharma Inc.
ANDA213719	70710-1273	sacubitril and valsartan sacubitril and valsartan	ANDA	Zydus Pharmaceuticals USA Inc.
ANDA213808	70748-196	sacubitril and valsartan sacubitril and valsartan	ANDA	Lupin Pharmaceuticals, Inc.

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 84 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
00904758204	rxnav_ndcs	yes
13668063505	rxnav_ndcs	yes
13668063533	rxnav_ndcs	yes
13668063560	rxnav_ndcs	yes
13668063571	rxnav_ndcs	yes
13668063574	rxnav_ndcs	yes
13668074605	rxnav_ndcs	yes
13668074633	rxnav_ndcs	yes
13668074660	rxnav_ndcs	yes
13668074671	rxnav_ndcs	yes
13668074674	rxnav_ndcs	yes
31722067418	rxnav_ndcs	yes
31722067460	rxnav_ndcs	yes
33342057109	rxnav_ndcs	yes
33342057157	rxnav_ndcs	yes
42385093110	rxnav_ndcs	yes
42385093117	rxnav_ndcs	yes
42385093118	rxnav_ndcs	yes
42385093130	rxnav_ndcs	yes
42385093160	rxnav_ndcs	yes
42385093168	rxnav_ndcs	yes
42385093172	rxnav_ndcs	yes
43598064418	rxnav_ndcs	yes
43598064460	rxnav_ndcs	yes
46708055710	rxnav_ndcs	yes
46708055745	rxnav_ndcs	yes
46708055760	rxnav_ndcs	yes
46708055791	rxnav_ndcs	yes
50268060711	rxnav_ndcs	yes
50268060715	rxnav_ndcs	yes
51407093610	rxnav_ndcs	yes
60290008601	rxnav_ndcs	yes
60290008602	rxnav_ndcs	yes
60290008603	rxnav_ndcs	yes
60687096611	rxnav_ndcs	yes
60687096657	rxnav_ndcs	yes
62332055710	rxnav_ndcs	yes
62332055745	rxnav_ndcs	yes
62332055760	rxnav_ndcs	yes
62332055791	rxnav_ndcs	yes
67877070851	rxnav_ndcs	yes
67877070860	rxnav_ndcs	yes
67877094933	rxnav_ndcs	yes
67877094951	rxnav_ndcs	yes
67877094960	rxnav_ndcs	yes
69238273201	rxnav_ndcs	yes
69238273202	rxnav_ndcs	yes
70069085460	rxnav_ndcs	yes
70069085480	rxnav_ndcs	yes
70377003211	rxnav_ndcs	yes
70377003212	rxnav_ndcs	yes
70377003213	rxnav_ndcs	yes
70377003214	rxnav_ndcs	yes
70710127302	rxnav_ndcs	yes
70710127304	rxnav_ndcs	yes
70710127306	rxnav_ndcs	yes
70710127308	rxnav_ndcs	yes
70748019607	rxnav_ndcs	yes
70771192202	rxnav_ndcs	yes
70771192204	rxnav_ndcs	yes
70771192206	rxnav_ndcs	yes
70771192208	rxnav_ndcs	yes
70954097620	rxnav_ndcs	yes
70954097630	rxnav_ndcs	yes
70954097650	rxnav_ndcs	yes
71610093932	rxnav_ndcs	yes
71610093989	rxnav_ndcs	yes
71610098289	rxnav_ndcs	yes
72205028118	rxnav_ndcs	yes
72205028160	rxnav_ndcs	yes
72603088101	rxnav_ndcs	yes
72603088102	rxnav_ndcs	yes
72865031110	rxnav_ndcs	yes
72865031118	rxnav_ndcs	yes
72865031160	rxnav_ndcs	yes
73190000610	rxnav_ndcs	yes
73190000618	rxnav_ndcs	yes
73190000660	rxnav_ndcs	yes
73190001818	rxnav_ndcs	yes
73190001860	rxnav_ndcs	yes
82293002810	rxnav_ndcs	yes
82293002820	rxnav_ndcs	yes
82293002830	rxnav_ndcs	yes
82293002831	rxnav_ndcs	yes

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 2 · 28 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
ENTRESTO	SACUBITRIL AND VALSARTAN	Novartis Pharmaceuticals Corporation	000dc81d-ab91-450c-8eae-8eb74e72296f	2026-07-06	Boxed warning, Warnings, Adverse reactions	Exact identifier rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	NorthStar RxLLC	998db1e1-3f32-4812-a64b-5a6870ef7f8f	2026-06-22	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 72603-881-01 ndc (package): 72603-881-02 ndc (product): 72603-881 ndc11 (package): 72603088101 ndc11 (package): 72603088102 rxcui: 1656349
sacubitril and valsartan	SACUBITRIL AND VALSARTAN	Torrent Pharmaceuticals Limited	59b7a07a-96ee-44b1-8dae-2b42169aa2c5	2026-06-18	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 13668-746-05 ndc (package): 13668-635-60 ndc (package): 13668-746-74 ndc (package): 13668-635-05 ndc (package): 13668-635-74 ndc (package): 13668-635-33 ndc (package): 13668-746-33 ndc (package): 13668-746-60 ndc (product): 13668-746 ndc (product): 13668-635 ndc11 (package): 13668074671 ndc11 (package): 13668063533 ndc11 (package): 13668063505 ndc11 (package): 13668074660 ndc11 (package): 13668074605 ndc11 (package): 13668063560 ndc11 (package): 13668074633 ndc11 (package): 13668063571 ndc11 (package): 13668074674 ndc11 (package): 13668063574 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	American Health Packaging	d85015d5-f619-4a58-b6ab-5e39af3f79d8	2026-06-11	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 60687-966-57 ndc (product): 60687-966 ndc11 (package): 60687096657 ndc11 (package): 60687096611 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	ANI Pharmaceuticals, Inc.	a1fa7066-8ab4-47e3-a701-6c5170700d11	2026-05-27	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 70954-976-30 ndc (package): 70954-976-20 ndc (package): 70954-976-50 ndc (product): 70954-976 ndc11 (package): 70954097630 ndc11 (package): 70954097620 ndc11 (package): 70954097650 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	XLCare Pharmaceuticals Inc	064a7c51-de30-4759-8210-e18438e6a187	2026-04-01	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 72865-311-18 ndc (package): 72865-311-10 ndc (package): 72865-311-60 ndc (product): 72865-311 ndc11 (package): 72865031110 ndc11 (package): 72865031160 ndc11 (package): 72865031118 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Novugen Pharma (USA) LLC	747eeb5c-ac2f-474f-b6d2-0586d12653a6	2026-03-17	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 82293-028-20 ndc (package): 82293-028-30 ndc (package): 82293-028-10 ndc (product): 82293-028 ndc11 (package): 82293002831 ndc11 (package): 82293002820 ndc11 (package): 82293002810 ndc11 (package): 82293002830 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Somerset Therapeutics, LLC	4f88efbb-3718-43a1-91d4-da5943ccfca1	2026-02-21	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 70069-854-60 ndc (package): 70069-854-80 ndc (product): 70069-854 ndc11 (package): 70069085460 ndc11 (package): 70069085480 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Aphena Pharma Solutions - Tennessee, LLC	48714b95-b4ac-ef3c-e063-6294a90a9a5b	2026-01-15	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 71610-982-89 ndc (product): 71610-982 ndc11 (package): 71610098289 rxcui: 1656349
sacubitril and valsartan	SACUBITRIL AND VALSARTAN	Golden State Medical Supply, Inc.	8290ae4c-0d1e-47f6-8029-ddc1c0bd6f6d	2025-11-22	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 51407-936-10 ndc (product): 51407-936 ndc11 (package): 51407093610 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	AvKARE	43bcdbc7-a635-bb4e-e063-6294a90a990f	2025-11-16	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 73190-018-18 ndc (package): 73190-018-60 ndc (product): 73190-018 ndc11 (package): 73190001860 ndc11 (package): 73190001818 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Major Pharmaceuticals	f2cba3db-0256-422a-a8a4-7afb3a9970d0	2025-10-28	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 0904-7582-04 ndc (product): 0904-7582 ndc11 (package): 00904758204 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	AvPAK	4114a976-2e58-8437-e063-6394a90af298	2025-10-13	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 50268-607-15 ndc (product): 50268-607 ndc11 (package): 50268060711 ndc11 (package): 50268060715 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Aphena Pharma Solutions - Tennessee, LLC	3cf9da3f-42b7-df11-e063-6294a90ad40b	2025-09-02	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 71610-939-89 ndc (package): 71610-939-32 ndc (product): 71610-939 ndc11 (package): 71610093989 ndc11 (package): 71610093932 rxcui: 1656349
sacubitril and valsartan	SACUBITRIL AND VALSARTAN	Lupin Pharmaceuticals, Inc.	76cbb87b-6356-4ead-af7f-faffb6e79743	2025-07-29	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 70748-196-07 ndc (product): 70748-196 ndc11 (package): 70748019607 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Ascend Laboratories, LLC	a0f23b69-5a1b-4aa8-8f0c-5818bd609492	2025-07-24	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 67877-949-51 ndc (package): 67877-949-60 ndc (package): 67877-949-33 ndc (product): 67877-949 ndc11 (package): 67877094933 ndc11 (package): 67877094951 ndc11 (package): 67877094960 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Novadoz Pharmaceuticals LLC	44db8114-622e-41f6-96a1-447d47b0267c	2025-07-24	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 72205-281-60 ndc (package): 72205-281-18 ndc (product): 72205-281 ndc11 (package): 72205028118 ndc11 (package): 72205028160 rxcui: 1656349
Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Ascend Laboratories, LLC	98d838f6-03a9-43e9-b8dd-8882c6df1631	2025-07-24	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 67877-708-60 ndc (package): 67877-708-51 ndc (product): 67877-708 ndc11 (package): 67877070851 ndc11 (package): 67877070860 rxcui: 1656349
Sacubitril and valsartan	SACUBITRIL AND VALSARTAN	Camber Pharmaceuticals, Inc.	65a3e298-279d-4498-a7be-5f9ee5bc77d8	2025-07-23	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 31722-674-60 ndc (package): 31722-674-18 ndc (product): 31722-674 ndc11 (package): 31722067460 ndc11 (package): 31722067418 rxcui: 1656349
Sacubitril and Valsartan Sacubitril and Valsartan	SACUBITRIL AND VALSARTAN	Dr. Reddy's Laboratories Inc.	f4789255-b59b-544b-bbbe-2edd07da6079	2025-07-08	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 43598-644-60 ndc (package): 43598-644-18 ndc (product): 43598-644 ndc11 (package): 43598064460 ndc11 (package): 43598064418 rxcui: 1656349

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 28 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
000dc81d-ab91-450c-8eae-8eb74e72296f	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	24	These highlights do not include all the information needed to use ENTRESTO safely and effectively. See full prescribing information for ENTRESTO. ENTRESTO ® (sacubitril and valsartan) tablets, for oral use ENTRESTO ® SPRINKLE (sacubitril and valsartan) oral pellets Initial U.S. Approval: 2015	20251029
98d838f6-03a9-43e9-b8dd-8882c6df1631	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	12	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250724
59b7a07a-96ee-44b1-8dae-2b42169aa2c5	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	12	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250715
76cbb87b-6356-4ead-af7f-faffb6e79743	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	11	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250729
5928f174-83e5-4c74-b15a-138338a70295	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	10	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20241103
f4789255-b59b-544b-bbbe-2edd07da6079	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	9	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250708
7de9b8e0-195a-b59e-7bbf-3e95c4096af9	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	5	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250717
2c39c326-34a2-b7f4-e063-6294a90a6732	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	4	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	20260303
4f88efbb-3718-43a1-91d4-da5943ccfca1	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	3	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval:2015	20260221
e4011f11-2035-4f32-8df6-b1580c2a6e2a	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	3	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250218
a1fa7066-8ab4-47e3-a701-6c5170700d11	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20260527
064a7c51-de30-4759-8210-e18438e6a187	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20260401
747eeb5c-ac2f-474f-b6d2-0586d12653a6	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20260317
4114a976-2e58-8437-e063-6394a90af298	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	20251013
3cf9da3f-42b7-df11-e063-6294a90ad40b	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	20250902
44db8114-622e-41f6-96a1-447d47b0267c	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250724
a0f23b69-5a1b-4aa8-8f0c-5818bd609492	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250724
65a3e298-279d-4498-a7be-5f9ee5bc77d8	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250723
4ed0dbe4-8752-43c5-8c28-17c9638a52d6	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	2	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250708
d85015d5-f619-4a58-b6ab-5e39af3f79d8	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20260515
48714b95-b4ac-ef3c-e063-6294a90a9a5b	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20260115
43bcdbc7-a635-bb4e-e063-6294a90a990f	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	20251116
f2cba3db-0256-422a-a8a4-7afb3a9970d0	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20251028
4c871c01-0564-411f-87e2-478aa42503cf	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	Sacubitril and Valsartan Tablets	20250708
103c39e2-f3c8-40fc-a57e-3af018fb4af4	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20250626
b47b5c7e-1c20-429c-9560-07f5f06cdce3	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20241107
e4716fc9-5f73-4303-8a4e-e8f9129b6e2d	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	20241103
14bf8041-0b7f-9acb-e063-6294a90a8256	sacubitril 49 MG / valsartan 51 MG Oral Tablet [PSN] · sacubitril 49 MG / valsartan 51 MG Oral Tablet [SCD]	2	1	These highlights do not include all the information needed to use ENTRESTO safely and effectively. See full prescribing information for ENTRESTO. ENTRESTO ® (sacubitril and valsartan) tablets, for oral use Initial U.S. Approval: 2015	20240328

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
3173e592-6f28-4864-9bf0-0ef0452da3de	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Umedica Laboratories USA Inc. \| UMEDICA LABORATORIES PRIVATE LIMITED	20261023
3173e592-6f28-4864-9bf0-0ef0452da3de	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Umedica Laboratories USA Inc. \| UMEDICA LABORATORIES PRIVATE LIMITED	20261014
2c39c326-34a2-b7f4-e063-6294a90a6732	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	AvKARE	20261007
3173e592-6f28-4864-9bf0-0ef0452da3de	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Umedica Laboratories USA Inc. \| UMEDICA LABORATORIES PRIVATE LIMITED	20260807
998db1e1-3f32-4812-a64b-5a6870ef7f8f	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	NorthStar RxLLC \| Macleods Pharmaceuticals Limited	20260622
59b7a07a-96ee-44b1-8dae-2b42169aa2c5	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Torrent Pharmaceuticals Limited \| Torrent Pharma, Inc.	20260618
d85015d5-f619-4a58-b6ab-5e39af3f79d8	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	American Health Packaging	20260611
a1fa7066-8ab4-47e3-a701-6c5170700d11	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	ANI Pharmaceuticals, Inc.	20260527
d85015d5-f619-4a58-b6ab-5e39af3f79d8	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	American Health Packaging	20260515
064a7c51-de30-4759-8210-e18438e6a187	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	XLCare Pharmaceuticals Inc \| Evaric Pharmaceuticals Inc	20260401
747eeb5c-ac2f-474f-b6d2-0586d12653a6	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Novugen Pharma (USA) LLC \| Novugen Pharma Sdn. Bhd. \| Aizant Drug Research Solutions Pvt. Ltd.	20260317
2c39c326-34a2-b7f4-e063-6294a90a6732	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	AvKARE	20260303
2c39c326-34a2-b7f4-e063-6294a90a6732	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	AvKARE	20260225
4f88efbb-3718-43a1-91d4-da5943ccfca1	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval:2015	Somerset Therapeutics, LLC \| Synthon Chile Limitada	20260221
48714b95-b4ac-ef3c-e063-6294a90a9a5b	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Aphena Pharma Solutions - Tennessee, LLC	20260115
8290ae4c-0d1e-47f6-8029-ddc1c0bd6f6d	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Golden State Medical Supply, Inc. \| Bora Pharmaceuticals Inc.	20251122
43bcdbc7-a635-bb4e-e063-6294a90a990f	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	AvKARE	20251116
f2cba3db-0256-422a-a8a4-7afb3a9970d0	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Major Pharmaceuticals \| Alkem Laboratories Limited	20251028
4114a976-2e58-8437-e063-6394a90af298	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	AvPAK	20251013
064a7c51-de30-4759-8210-e18438e6a187	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	XLCare Pharmaceuticals Inc \| Evaric Pharmaceuticals Inc	20250930
2c39c326-34a2-b7f4-e063-6294a90a6732	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	AvKARE	20250903
3cf9da3f-42b7-df11-e063-6294a90ad40b	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	Aphena Pharma Solutions - Tennessee, LLC	20250902
3cf9da3f-42b7-df11-e063-6294a90ad40b	SACUBITRIL AND VALSARTAN tablets, for oral use These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. Initial U.S. Approval: 2015	Aphena Pharma Solutions - Tennessee, LLC	20250822
76cbb87b-6356-4ead-af7f-faffb6e79743	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Lupin Pharmaceuticals, Inc. \| LUPIN LIMITED \| AET LABORATORIES PRIVATE LIMITED	20250729
98d838f6-03a9-43e9-b8dd-8882c6df1631	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Ascend Laboratories, LLC \| Alkem Laboratories Limited	20250724
44db8114-622e-41f6-96a1-447d47b0267c	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Novadoz Pharmaceuticals LLC \| MSN LABORATORIES PRIVATE LIMITED	20250724
a0f23b69-5a1b-4aa8-8f0c-5818bd609492	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Ascend Laboratories, LLC \| Alkem Laboratories Limited	20250724
65a3e298-279d-4498-a7be-5f9ee5bc77d8	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Camber Pharmaceuticals, Inc. \| Hetero Labs Limited Unit III	20250723
7de9b8e0-195a-b59e-7bbf-3e95c4096af9	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Biocon Pharma Inc. \| Biocon Pharma Limited	20250717
7de9b8e0-195a-b59e-7bbf-3e95c4096af9	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Biocon Pharma Inc. \| Biocon Pharma Limited	20250717
59b7a07a-96ee-44b1-8dae-2b42169aa2c5	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Torrent Pharmaceuticals Limited \| Torrent Pharma, Inc.	20250715
f4789255-b59b-544b-bbbe-2edd07da6079	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Dr. Reddy's Laboratories Inc. \| Dr. Reddy's Laboratories Limited	20250708
4ed0dbe4-8752-43c5-8c28-17c9638a52d6	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Zydus Pharmaceuticals USA Inc. \| Zydus Lifesciences Limited	20250708
4c871c01-0564-411f-87e2-478aa42503cf	Sacubitril and Valsartan Tablets	Zydus Lifesciences Limited	20250708
103c39e2-f3c8-40fc-a57e-3af018fb4af4	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Macleods Pharmaceuticals Limited	20250626
e4011f11-2035-4f32-8df6-b1580c2a6e2a	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Amneal Pharmaceuticals NY LLC \| HARMAN FINOCHEM LIMITED	20250218
b47b5c7e-1c20-429c-9560-07f5f06cdce3	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL AND VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Laurus Labs Limited \| Laurus Labs Limited (VSP2)	20241107
5928f174-83e5-4c74-b15a-138338a70295	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Alembic Pharmaceuticals Inc. \| Alembic Pharmaceuticals Limited	20241103
e4716fc9-5f73-4303-8a4e-e8f9129b6e2d	These highlights do not include all the information needed to use SACUBITRIL AND VALSARTAN TABLETS safely and effectively. See full prescribing information for SACUBITRIL AND VALSARTAN TABLETS. SACUBITRIL and VALSARTAN tablets, for oral use Initial U.S. Approval: 2015	Alembic Pharmaceuticals Limited	20241103

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C09DX	Angiotensin II receptor blockers (ARBs), other combinations	ATC1-4		sacubitril / valsartan
ATC	C09CA	Angiotensin II receptor blockers (ARBs), plain	ATC1-4		valsartan
FDASPL	N0000175561	Angiotensin 2 Receptor Blocker	EPC	has_epc	valsartan
FDASPL	N0000000070	Angiotensin 2 Receptor Antagonists	MOA	has_moa	valsartan
MEDRT	D000613	Aminobutyrates	CHEM	has_ingredient	sacubitril
MEDRT	D001713	Biphenyl Compounds	CHEM	has_ingredient	sacubitril
MEDRT	D000068756	Valsartan	CHEM	has_ingredient	valsartan
MEDRT	D003928	Diabetic Nephropathies	DISEASE	may_treat	valsartan
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	sacubitril
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	valsartan
MEDRT	D006333	Heart Failure	DISEASE	may_prevent	sacubitril
MEDRT	D006333	Heart Failure	DISEASE	may_treat	valsartan
MEDRT	D006929	Hyperaldosteronism	DISEASE	ci_with	valsartan
MEDRT	D006973	Hypertension	DISEASE	may_treat	valsartan
MEDRT	D007022	Hypotension	DISEASE	ci_with	valsartan
MEDRT	D011247	Pregnancy	DISEASE	ci_with	valsartan
MEDRT	D018487	Ventricular Dysfunction, Left	DISEASE	may_treat	valsartan
MEDRT	N0000000070	Angiotensin 2 Receptor Antagonists	MOA	has_moa	valsartan
MEDRT	N0000191727	Neprilysin Inhibitors	MOA	has_moa	sacubitril
MEDRT	N0000178477	Decreased Blood Pressure	PE	has_pe	valsartan
MEDRT	N0000008669	Decreased Intravascular Volume	PE	has_pe	valsartan
MEDRT	N0000008731	Decreased Mineralocorticoid Secretion	PE	has_pe	valsartan
MEDRT	N0000008859	Decreased Renal K+ Excretion	PE	has_pe	valsartan
MEDRT	N0000009553	Increased Renal Na+ Excretion	PE	has_pe	valsartan
MEDRT	N0000009825	Renal Arterial Vasoconstriction	PE	ci_pe	valsartan
MEDRT	N0000009826	Renal Arterial Vasodilation	PE	has_pe	valsartan

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Entresto	rxnav_allrelated
DF	DF	Oral Tablet	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
DFG	DFG	Pill	rxnav_allrelated
IN	IN	sacubitril	rxnav_allrelated
IN	IN	valsartan	rxnav_allrelated
MIN	MIN	sacubitril / valsartan	rxnav_allrelated
SBD	SBD	sacubitril 49 MG / valsartan 51 MG Oral Tablet [Entresto]	rxnav_allrelated
SBDC	SBDC	sacubitril 49 MG / valsartan 51 MG [Entresto]	rxnav_allrelated
SBDF	SBDF	sacubitril / valsartan Oral Tablet [Entresto]	rxnav_allrelated
SBDG	SBDG	Entresto Oral Product	rxnav_allrelated
SBDG	SBDG	Entresto Pill	rxnav_allrelated
SCD	SCD	sacubitril 49 MG / valsartan 51 MG Oral Tablet	rxnav_allrelated
SCDC	SCDC	sacubitril 49 MG	rxnav_allrelated
SCDC	SCDC	valsartan 51 MG	rxnav_allrelated
SCDF	SCDF	sacubitril / valsartan Oral Tablet	rxnav_allrelated
SCDG	SCDG	sacubitril / valsartan Oral Product	rxnav_allrelated
SCDG	SCDG	sacubitril / valsartan Pill	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	49 MG / 51 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
CODES	ANDA	ANDA213604
CODES	ANDA	ANDA213605
CODES	ANDA	ANDA213611
CODES	ANDA	ANDA213627
CODES	ANDA	ANDA213668
CODES	ANDA	ANDA213676
CODES	ANDA	ANDA213680
CODES	ANDA	ANDA213682
CODES	ANDA	ANDA213719
CODES	ANDA	ANDA213728
CODES	ANDA	ANDA213748
CODES	ANDA	ANDA213764
CODES	ANDA	ANDA213808
CODES	ANDA	ANDA219946
CODES	ANDA	ANDA219983
CODES	SNOMEDCT	1162682004
CODES	VUID	4034604
CODES	VUID	4034607
NAMES	Prescribable Synonym	sacubitril 49 MG / valsartan 51 MG Oral Tablet
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Micromedex RED BOOK
SOURCES	Source	Multum MediSource Lexicon
SOURCES	Source	National Drug Data File Plus Source Vocabulary
SOURCES	Source	US Edition of SNOMED_CT
SOURCES	Source	Veterans Health Administration National Drug File