LUMACAFTOR
Substance profile for UNII EGP8L81APK, enriched with FDA NDC listings, DailyMed labels, legacy aliases, and open chemistry identifiers.
Substance Identity#
- UNII
- EGP8L81APK
- Preferred term
- LUMACAFTOR
- Registry number
- 936727-05-8
- Ingredient type
- INGREDIENT SUBSTANCE
- Molecular formula
- C24H18F2N2O5
Chemical And Database Identifiers#
- InChIKey
- UFSKUSARDNFIRC-UHFFFAOYSA-N
- SMILES
- CC1=CC=C(NC(=O)C2(CC2)C3=CC4=C(OC(F)(F)O4)C=C3)N=C1C5=CC=CC(=C5)C(O)=O
- RxCUI
- 1655922
- PubChem
- 16678941
- INN ID
- 9449
Open Chemistry Sources#
| Source | Identifier | Link |
|---|---|---|
| PubChem Compound | 16678941 |  pubchem.ncbi.nlm.nih.gov/compound/16678941 |
| PubChem InChIKey Search | UFSKUSARDNFIRC-UHFFFAOYSA-N | pubchem.ncbi.nlm.nih.gov/#query=UFSKUSARDNFIRC-UHFFFAOYSA-N |
| RxNorm | 1655922 |  mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=1655922 |
| FDA Substance Registration System | EGP8L81APK |  precision.fda.gov/uniisearch/srs/unii/EGP8L81APK |
DailyMed Socrata Ingredients#
| Ingredient | Type | UNII | DailyMed label | SPL version | Uploaded |
|---|---|---|---|---|---|
| lumacaftor | ACTIVE INGREDIENT | EGP8L81APK | ORKAMBI (LUMACAFTOR AND IVACAFTOR) TABLET, FILM COATED [VERTEX PHARMACEUTICALS INCORPORATED] | 1 | |
| lumacaftor | ACTIVE MOIETY | EGP8L81APK | ORKAMBI (LUMACAFTOR AND IVACAFTOR) TABLET, FILM COATED [VERTEX PHARMACEUTICALS INCORPORATED] | 1 |