Application 019781

Type
NDA
Sponsor
VIRTUS PHARMS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001PROMETRIUMPROGESTERONECAPSULE;ORAL100MGYesNo
002PROMETRIUMPROGESTERONECAPSULE;ORAL200MGYesYes
003PROMETRIUMPROGESTERONECAPSULE;ORAL300MGNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019781-001PROMETRIUMPROGESTERONE100MGCAPSULE / ORALABRLD1998-05-14
N019781-002PROMETRIUMPROGESTERONE200MGCAPSULE / ORALABRLD, RS1999-10-15
N019781-003PROMETRIUMPROGESTERONE300MGCAPSULE / ORAL1999-10-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N019781-001AB
N019781-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-142680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-152680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-145bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-155bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14d06236e962d9…
2024-10-29 15:01 UTC2024-10N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15d06236e962d9…
2024-10-29 15:01 UTC2024-10N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-1479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-1579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-141e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-151e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-148072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N019781-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019781-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019781-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019781-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019781-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019781-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019781-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N019781-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019781-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019781-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N019781-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N019781-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N019781-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N019781-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N019781-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N019781-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N019781-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N019781-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N019781-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N019781-002AB1782e0a99824c…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PrometriumPROGESTERONEAcertis Pharmaceuticals, LLC1cf237ff-c4f8-4faa-a7aa-77599c8568892026-07-23Warnings, Adverse reactionsExact identifier
application applno (NDA): 019781
application number: NDA019781
ndc (product): 72989-373
ndc (product): 72989-372

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 24 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
50090-3240ProgesteroneProgesteroneA-S Medication SolutionsNDACurrent
50090-3240ProgesteroneProgesteroneA-S Medication SolutionsNDACurrent
50090-3240ProgesteroneProgesteroneA-S Medication SolutionsNDACurrent
63629-7475ProgesteroneProgesteroneBryant Ranch PrepackNDACurrent
63629-7475ProgesteroneProgesteroneBryant Ranch PrepackNDACurrent
63629-7475ProgesteroneProgesteroneBryant Ranch PrepackNDACurrent
63629-8530ProgesteroneProgesteroneBryant Ranch PrepackNDACurrent
63629-8530ProgesteroneProgesteroneBryant Ranch PrepackNDACurrent
69543-372PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-372PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-372PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-372PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-373PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-373PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-373PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-373PrometriumProgesteroneVirtus PharmaceuticalsNDACurrent
69543-374ProgesteroneProgesteroneVirtus PharmaceuticalsNDACurrent
69543-374ProgesteroneProgesteroneVirtus PharmaceuticalsNDACurrent
69543-374ProgesteroneProgesteroneVirtus PharmaceuticalsNDACurrent
69543-375ProgesteroneProgesteroneVirtus PharmaceuticalsNDACurrent
69543-375ProgesteroneProgesteroneVirtus PharmaceuticalsNDACurrent
69543-375ProgesteroneProgesteroneVirtus PharmaceuticalsNDACurrent
72989-372PrometriumProgesteroneAcertis Pharmaceuticals, LLCNDACurrent
72989-373PrometriumProgesteroneAcertis Pharmaceuticals, LLCNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
85032SUPPL 2026-02-12
85013SUPPL 2026-02-12
77562SUPPL 2024-02-20
77536SUPPL 2024-02-16
71518SUPPL2022-07-05
71513SUPPL2022-07-05
11715SUPPL2011-11-04
19215SUPPL2011-11-03
1615SUPPL2009-07-07
33950SUPPL2009-07-06
19214SUPPL2004-03-10
20350ORIG1998-05-14
11714ORIG1998-05-14
1614ORIG1998-05-14