Application 019865

Type
NDA
Sponsor
COVIS PHARMA BV

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001BETAPACESOTALOL HYDROCHLORIDETABLET;ORAL80MGYesNo
002BETAPACESOTALOL HYDROCHLORIDETABLET;ORAL160MGYesYes
003BETAPACESOTALOL HYDROCHLORIDETABLET;ORAL240MGYesNo
004BETAPACESOTALOL HYDROCHLORIDETABLET;ORAL320MGNoNo
005BETAPACESOTALOL HYDROCHLORIDETABLET;ORAL120MGYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 5 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019865-001BETAPACESOTALOL HYDROCHLORIDE80MGTABLET / ORALABRLD1992-10-30
N019865-002BETAPACESOTALOL HYDROCHLORIDE160MGTABLET / ORALABRLD, RS1992-10-30
N019865-003BETAPACESOTALOL HYDROCHLORIDE240MGTABLET / ORALABRLD1992-10-30
N019865-004BETAPACESOTALOL HYDROCHLORIDE320MGTABLET / ORAL1992-10-30
N019865-005BETAPACESOTALOL HYDROCHLORIDE120MGTABLET / ORALABRLD1994-04-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
N019865-001AB
N019865-002AB
N019865-003AB
N019865-005AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 6 · 205 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019865-004BETAPACE320MGTABLET / ORAL1992-10-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-004BETAPACE320MGTABLET / ORAL1992-10-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019865-004BETAPACE320MGTABLET / ORAL1992-10-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-004BETAPACE320MGTABLET / ORAL1992-10-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-004BETAPACE320MGTABLET / ORAL1992-10-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-004BETAPACE320MGTABLET / ORAL1992-10-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-004BETAPACE320MGTABLET / ORAL1992-10-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-001BETAPACE80MGTABLET / ORALABRLD1992-10-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-002BETAPACE160MGTABLET / ORALABRLD, RS1992-10-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-003BETAPACE240MGTABLET / ORALABRLD1992-10-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-004BETAPACE320MGTABLET / ORAL1992-10-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-005BETAPACE120MGTABLET / ORALABRLD1994-04-205bbf6a4d5a75…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 5 · 164 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N019865-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019865-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019865-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019865-005AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019865-005AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019865-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019865-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019865-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019865-005AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019865-005AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019865-005AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019865-005AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019865-005AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019865-005AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019865-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019865-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019865-003AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019865-005AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019865-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019865-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019865-003AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019865-005AB1d06236e962d9…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BETAPACESOTALOL HYDROCHLORIDELegacy Pharma USA, Inc.a6a7702f-36c9-45db-b640-453dc324baee2024-12-16Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019865
application number: NDA019865

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 18 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
13672-051Betapacesotalol HClSkyePharma Production SASNDACurrent
13672-051Betapacesotalol HClSkyepharma Production SASNDACurrent
13672-051Betapacesotalol HClSkyepharma Production SASNDACurrent
13672-052Betapacesotalol HClSkyePharma Production SASNDACurrent
13672-052Betapacesotalol HClSkyepharma Production SASNDACurrent
13672-052Betapacesotalol HClSkyepharma Production SASNDACurrent
13672-053Betapacesotalol HClSkyePharma Production SASNDACurrent
13672-053Betapacesotalol HClSkyepharma Production SASNDACurrent
13672-053Betapacesotalol HClSkyepharma Production SASNDACurrent
70515-105BETAPACEsotalol hydrochlorideCovis Pharma US, IncNDACurrent
70515-105BETAPACEsotalol hydrochlorideCovis PharmaNDACurrent
70515-105BETAPACEsotalol hydrochlorideCovis PharmaNDACurrent
70515-106BETAPACEsotalol hydrochlorideCovis Pharma US, IncNDACurrent
70515-106BETAPACEsotalol hydrochlorideCovis PharmaNDACurrent
70515-106BETAPACEsotalol hydrochlorideCovis PharmaNDACurrent
70515-109BETAPACEsotalol hydrochlorideCovis Pharma US, IncNDACurrent
70515-109BETAPACEsotalol hydrochlorideCovis PharmaNDACurrent
70515-109BETAPACEsotalol hydrochlorideCovis PharmaNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
74620SUPPL 2023-06-23
74505SUPPL 2023-06-16
67737SUPPL2021-06-08
67722SUPPL2021-06-07
19783SUPPL2016-05-17
11799SUPPL2016-05-11
34056SUPPL2011-08-24
19782SUPPL2011-08-18
19781SUPPL2011-02-09
34055SUPPL2011-02-04
41072SUPPL2002-06-19
19780SUPPL2001-10-01
11798SUPPL2001-10-01