Application 022081

Type: NDA
Sponsor: GILEAD

Application Products#

Product, Drug, Ingredient table
Product	Drug	Ingredient	Form	Strength	Reference drug	Reference standard
001	LETAIRIS	AMBRISENTAN	TABLET;ORAL	5MG	Yes	No
002	LETAIRIS	AMBRISENTAN	TABLET;ORAL	10MG	Yes	Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N022081-001	LETAIRIS	AMBRISENTAN	5MG	TABLET / ORAL	AB	RLD	2007-06-15
N022081-002	LETAIRIS	AMBRISENTAN	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
N022081-001	AB
N022081-002	AB

Orange Book patents#

Current patent rows page 1 of 1 · 6 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Submission date
N022081-001	8377933	2027-12-11	U-1754	2015-10-23
N022081-001	9474752	2027-12-11	U-1754	2016-11-23
N022081-001	9549926	2031-10-14	U-1965	2017-02-16
N022081-002	8377933	2027-12-11	U-1754	2015-10-23
N022081-002	9474752	2027-12-11	U-1754	2016-11-23
N022081-002	9549926	2031-10-14	U-1965	2017-02-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N022081-001	LETAIRIS	5MG	TABLET / ORAL	AB	RLD	2007-06-15	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N022081-002	LETAIRIS	10MG	TABLET / ORAL	AB	RLD, RS	2007-06-15	`782e0a99824c…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N022081-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022081-002	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-002	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N022081-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022081-002	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-002	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-002	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-002	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-002	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022081-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022081-002	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N022081-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N022081-002	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N022081-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N022081-002	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N022081-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N022081-002	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N022081-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N022081-002	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N022081-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N022081-002	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N022081-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N022081-002	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N022081-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N022081-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N022081-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N022081-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N022081-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N022081-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N022081-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N022081-002	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N022081-001	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	N022081-002	AB	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N022081-001	AB	1	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N022081-002	AB	1	`782e0a99824c…`

Observed Orange Book patent history#

Patent history page 1 of 7 · 246 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Submission date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N022081-001	8377933	2027-12-11	U-1754	2015-10-23	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022081-001	9474752	2027-12-11	U-1754	2016-11-23	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022081-001	9549926	2031-10-14	U-1965	2017-02-16	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022081-002	8377933	2027-12-11	U-1754	2015-10-23	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022081-002	9474752	2027-12-11	U-1754	2016-11-23	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022081-002	9549926	2031-10-14	U-1965	2017-02-16	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-001	8377933	2027-12-11	U-1754	2015-10-23	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-001	9474752	2027-12-11	U-1754	2016-11-23	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-001	9549926	2031-10-14	U-1965	2017-02-16	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-002	8377933	2027-12-11	U-1754	2015-10-23	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-002	9474752	2027-12-11	U-1754	2016-11-23	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022081-002	9549926	2031-10-14	U-1965	2017-02-16	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N022081-001	8377933	2027-12-11	U-1754	2015-10-23	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022081-001	9474752	2027-12-11	U-1754	2016-11-23	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022081-001	9549926	2031-10-14	U-1965	2017-02-16	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022081-002	8377933	2027-12-11	U-1754	2015-10-23	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022081-002	9474752	2027-12-11	U-1754	2016-11-23	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022081-002	9549926	2031-10-14	U-1965	2017-02-16	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-001	8377933	2027-12-11	U-1754	2015-10-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-001	9474752	2027-12-11	U-1754	2016-11-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-001	9549926	2031-10-14	U-1965	2017-02-16	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-002	8377933	2027-12-11	U-1754	2015-10-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-002	9474752	2027-12-11	U-1754	2016-11-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022081-002	9549926	2031-10-14	U-1965	2017-02-16	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-001	8377933	2027-12-11	U-1754	2015-10-23	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-001	9474752	2027-12-11	U-1754	2016-11-23	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-001	9549926	2031-10-14	U-1965	2017-02-16	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-002	8377933	2027-12-11	U-1754	2015-10-23	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-002	9474752	2027-12-11	U-1754	2016-11-23	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022081-002	9549926	2031-10-14	U-1965	2017-02-16	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-001	8377933	2027-12-11	U-1754	2015-10-23	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-001	9474752	2027-12-11	U-1754	2016-11-23	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-001	9549926	2031-10-14	U-1965	2017-02-16	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-002	8377933	2027-12-11	U-1754	2015-10-23	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-002	9474752	2027-12-11	U-1754	2016-11-23	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022081-002	9549926	2031-10-14	U-1965	2017-02-16	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-001	8377933	2027-12-11	U-1754	2015-10-23	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-001	9474752	2027-12-11	U-1754	2016-11-23	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-001	9549926	2031-10-14	U-1965	2017-02-16	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022081-002	8377933	2027-12-11	U-1754	2015-10-23	`2680178bc6a6…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Letairis	AMBRISENTAN	Gilead Sciences, Inc.	725d4e73-6c83-477a-adc6-0ae4a133a844	2026-06-22	Boxed warning, Warnings, Adverse reactions	Exact identifier application applno (NDA): 022081 application number: NDA022081 ndc (product): 61958-0801 ndc (product): 61958-0802

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 6 matching rows.

NDC, Name, Nonproprietary name table
NDC	Name	Nonproprietary name	Labeler	Marketing category	Status
61958-0801	Letairis	AMBRISENTAN	Gilead Sciences, Inc	NDA	Current
61958-0801	Letairis	AMBRISENTAN	Gilead Sciences, Inc	NDA	Current
61958-0801	Letairis	AMBRISENTAN	Gilead Sciences, Inc	NDA	Current
61958-0802	Letairis	AMBRISENTAN	Gilead Sciences, Inc	NDA	Current
61958-0802	Letairis	AMBRISENTAN	Gilead Sciences, Inc	NDA	Current
61958-0802	Letairis	AMBRISENTAN	Gilead Sciences, Inc	NDA	Current

Documents#

Document, Submission type, Date table
Document	Submission type	Date
81888	SUPPL	2025-04-08
81831	SUPPL	2025-04-07
79448	SUPPL	2024-08-20
76409	ORIG	2023-11-06
67748	SUPPL	2021-06-09
65715	SUPPL	2020-12-23
60998	SUPPL	2019-11-20
59843	SUPPL	2019-08-27
59842	SUPPL	2019-08-26
59841	SUPPL	2019-08-26
58173	APPL	2019-04-01
58154	SUPPL	2019-03-29
56659	SUPPL	2018-12-07
56614	SUPPL	2018-12-03
49890	SUPPL	2017-09-29
49073	SUPPL	2017-07-25
46218	SUPPL	2016-12-19
16915	SUPPL	2015-10-08
6848	SUPPL	2015-10-06
6847	SUPPL	2014-10-30
21933	SUPPL	2014-08-01
38205	SUPPL	2014-05-06
29220	SUPPL	2014-05-06
6846	SUPPL	2014-02-04
16914	SUPPL	2014-02-03
6845	SUPPL	2013-08-22
38203	SUPPL	2013-08-21
29219	SUPPL	2012-10-23
38204	SUPPL	2012-10-22
16913	SUPPL	2012-02-17
6841	SUPPL	2012-02-17
6844	SUPPL	2011-07-21
38202	SUPPL	2011-07-20
6843	SUPPL	2011-03-08
38201	SUPPL	2011-03-07
38200	SUPPL	2010-10-25
29218	SUPPL	2010-10-20
24016	ORIG	2010-09-01
6842	SUPPL	2010-08-26
29216	SUPPL	2009-11-24
23353	ORIG	2009-09-02
16911	SUPPL	2009-08-13
16912	SUPPL	2009-07-09
29217	SUPPL	2009-07-08
38199	SUPPL	2009-06-10
29215	SUPPL	2009-06-10
38198	SUPPL	2008-11-07
29214	SUPPL	2008-10-14
16910	SUPPL	2008-02-25
29213	SUPPL	2008-02-19
6840	SUPPL	2007-12-03
21932	ORIG	2007-08-21
6839	ORIG	2007-07-05
38197	ORIG	2007-06-27