Application 022572

Type
NDA
Sponsor
MOBIUS THERAP

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001MITOSOLMITOMYCINFOR SOLUTION;TOPICAL0.2MG/VIALYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N022572-001MITOSOLMITOMYCIN0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07

Orange Book patents#

Current patent rows page 1 of 1 · 5 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N022572-00181865112026-07-19Drug product2012-06-25
N022572-00192050752026-07-19Drug product2016-01-06
N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10
N022572-00178062652029-02-01Drug product2012-03-22
N022572-00196494282029-05-21U-20952017-06-09

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-074b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0774a2ff9319b5…
2022-03-09 01:35 UTC2022-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0787673890dc5c…
2021-03-12 10:30 UTC2021-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-078869cabd3fbd…
2020-11-12 02:37 UTC2020-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07c0c555d07b60…
2019-12-14 00:12 UTC2019-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073f01610625f2…
2019-09-15 20:21 UTC2019-09N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07b00525d2431f…
2019-07-19 19:46 UTC2019-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-076a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-071c564ffb4f44…
2023-12-20 04:57 UTC2023-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-079b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073f0d92c62455…
2023-05-13 08:27 UTC2023-05N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07053a50430f4f…
2023-01-26 05:58 UTC2023-01N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 6 · 210 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N022572-00181865112026-07-19Drug product2012-06-25caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00192050752026-07-19Drug product2016-01-06caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00178062652029-02-01Drug product2012-03-22caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00196494282029-05-21U-20952017-06-09caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N022572-00181865112026-07-19Drug product2012-06-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00192050752026-07-19Drug product2016-01-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00178062652029-02-01Drug product2012-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00196494282029-05-21U-20952017-06-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00181865112026-07-19Drug product2012-06-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00192050752026-07-19Drug product2016-01-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00178062652029-02-01Drug product2012-03-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00196494282029-05-21U-20952017-06-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N022572-00181865112026-07-19Drug product2012-06-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00192050752026-07-19Drug product2016-01-066a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00178062652029-02-01Drug product2012-03-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00196494282029-05-21U-20952017-06-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00181865112026-07-19Drug product2012-06-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00192050752026-07-19Drug product2016-01-06fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00178062652029-02-01Drug product2012-03-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00196494282029-05-21U-20952017-06-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00181865112026-07-19Drug product2012-06-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00192050752026-07-19Drug product2016-01-06b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00178062652029-02-01Drug product2012-03-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00196494282029-05-21U-20952017-06-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00181865112026-07-19Drug product2012-06-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00192050752026-07-19Drug product2016-01-0603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-1003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00178062652029-02-01Drug product2012-03-2203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00196494282029-05-21U-20952017-06-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00181865112026-07-19Drug product2012-06-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00192050752026-07-19Drug product2016-01-062680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-102680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00178062652029-02-01Drug product2012-03-222680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00196494282029-05-21U-20952017-06-092680178bc6a6…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12N022572-001ODE-212019-02-0774a2ff9319b5…
2019-12-14 00:12 UTC2019-12N022572-001ODE-212019-02-073f01610625f2…
2019-09-15 20:21 UTC2019-09N022572-001ODE-212019-02-07b00525d2431f…
2019-07-19 19:46 UTC2019-07N022572-001ODE-212019-02-07ea99ee380514…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MitosolMITOMYCINMobius Therapeutics LLC244002c6-c61d-43fe-9326-0727971139792025-04-23Warnings, Adverse reactionsExact identifier
application applno (NDA): 022572
application number: NDA022572
ndc (product): 49771-002

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 4 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
49771-002MitosolmitomycinMobius Therapeutics LLCNDACurrent
49771-002MitosolmitomycinMobius Therapeutics LLCNDACurrent
49771-002MitosolmitomycinMobius Therapeutics LLCNDACurrent
49771-002MitosolmitomycinMobius Therapeutics LLCNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
67261SUPPL2021-04-29
67182SUPPL2021-04-27
64253SUPPL2020-08-10
50932SUPPL2017-12-27
50911SUPPL2017-12-27
38856SUPPL2016-01-26
29873SUPPL2016-01-21
38855SUPPL2014-09-30
7556SUPPL2014-09-29
24344ORIG2013-01-02
22061ORIG2013-01-02
29872ORIG2012-02-14
17726ORIG2012-02-09