Application 202207

Type
NDA
Sponsor
CARDINAL HEALTH 414

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001LYMPHOSEEK KITTECHNETIUM TC-99M TILMANOCEPTINJECTABLE;INJECTIONN/AYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N202207-001LYMPHOSEEK KITTECHNETIUM TC-99M TILMANOCEPTN/AINJECTABLE / INJECTIONRLD, RS2013-03-13

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N202207-00194399852029-01-30Drug product2016-10-14

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133f01610625f2…
2019-09-15 20:21 UTC2019-09N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-131c564ffb4f44…
2023-12-20 04:57 UTC2023-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-139b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133f0d92c62455…
2023-05-13 08:27 UTC2023-05N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13053a50430f4f…
2023-01-26 05:58 UTC2023-01N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 2 · 80 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N202207-00194399852029-01-30Drug product2016-10-14011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202207-00164099902025-05-12Drug substance31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202207-00194399852029-01-30Drug product2016-10-1431067a03dcf5…
2025-08-23 18:47 UTC2025-08N202207-00164099902025-05-12Drug substance6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202207-00194399852029-01-30Drug product2016-10-146a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202207-00164099902025-05-12Drug substancefd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202207-00194399852029-01-30Drug product2016-10-14fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202207-00164099902025-05-12Drug substanceb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202207-00194399852029-01-30Drug product2016-10-14b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-00164099902025-05-12Drug substance03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-00194399852029-01-30Drug product2016-10-1403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-00164099902025-05-12Drug substance2680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-00194399852029-01-30Drug product2016-10-142680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-00164099902025-05-12Drug substance5bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-00194399852029-01-30Drug product2016-10-145bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-00164099902025-05-12Drug substanced8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-00194399852029-01-30Drug product2016-10-14d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N202207-00164099902025-05-12Drug substanced06236e962d9…
2024-10-29 15:01 UTC2024-10N202207-00194399852029-01-30Drug product2016-10-14d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-00164099902025-05-12Drug substance79d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-00194399852029-01-30Drug product2016-10-1479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-00164099902025-05-12Drug substance301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-00194399852029-01-30Drug product2016-10-14301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-00164099902025-05-12Drug substance1e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-00194399852029-01-30Drug product2016-10-141e350fbaab3a…
2024-05-31 18:47 UTC2024-05N202207-00164099902025-05-12Drug substance8072bd15b7f6…
2024-05-31 18:47 UTC2024-05N202207-00194399852029-01-30Drug product2016-10-148072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-00164099902025-05-12Drug substance5c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-00194399852033-09-27Drug substance, Drug product2016-10-145c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N202207-00164099902025-05-12Drug substance5d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N202207-00194399852033-09-27Drug substance, Drug product2016-10-145d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N202207-00164099902025-05-12Drug substance4b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N202207-00194399852033-09-27Drug substance, Drug product2016-10-144b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N202207-00164099902020-05-12Drug substance74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N202207-00194399852033-09-27Drug substance, Drug product2016-10-1474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N202207-00164099902025-05-12Drug substancebb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N202207-00194399852033-09-27Drug substance, Drug product2016-10-14bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N202207-00164099902025-05-12Drug substance782e0a99824c…
2021-12-28 21:50 UTC2021-12N202207-00194399852033-09-27Drug substance, Drug product2016-10-14782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N202207-00164099902025-05-12Drug substance87673890dc5c…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-001NPP2024-05-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-001NPP2024-05-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-001NPP2024-05-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-001NPP2024-05-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N202207-001NPP2024-05-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-001NPP2024-05-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-001NPP2024-05-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-001NPP2024-05-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05N202207-001NPP2024-05-198072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-001NPP2024-05-195c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N202207-001NPP2024-05-195d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N202207-001NPP2024-05-194b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N202207-001ODE-672021-06-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N202207-001NPP2024-05-19bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N202207-001ODE-672021-06-13782e0a99824c…
2021-12-28 21:50 UTC2021-12N202207-001NPP2024-05-19782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N202207-001ODE-672021-06-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N202207-001ODE-672021-06-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N202207-001ODE-672021-06-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N202207-001ODE-672021-06-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N202207-001ODE-672021-06-133f01610625f2…
2019-09-15 20:21 UTC2019-09N202207-001ODE-672021-06-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N202207-001ODE-672021-06-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N202207-001NPP2024-05-196a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N202207-001NPP2024-05-191c564ffb4f44…
2023-12-20 04:57 UTC2023-12N202207-001NPP2024-05-19ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N202207-001NPP2024-05-19a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N202207-001NPP2024-05-199b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N202207-001NPP2024-05-19a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N202207-001NPP2024-05-193f0d92c62455…
2023-05-13 08:27 UTC2023-05N202207-001NPP2024-05-19053a50430f4f…
2023-01-26 05:58 UTC2023-01N202207-001NPP2024-05-193bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N202207-001NPP2024-05-193a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N202207-001NPP2024-05-19f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N202207-001NPP2024-05-19e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N202207-001NPP2024-05-19cb3db0bc1861…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)TILMANOCEPTCardinal Health 414, LLC72f31b09-4d7b-475c-b37a-9daf2ad802402025-09-08Warnings, Adverse reactionsExact identifier
application applno (NDA): 202207
application number: NDA202207
ndc (product): 65857-450
ndc (product): 65857-425

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 12 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
52579-1600Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptNavidea Biopharmaceuticals, Inc.NDACurrent
52579-1604Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptNavidea Biopharmaceuticals, Inc.NDACurrent
65857-425Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-425Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-425Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-425Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-425Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-450Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-450Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-450Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-450Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent
65857-450Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)tilmanoceptCardinal Health 414, LLCNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
67601SUPPL2021-05-26
67564SUPPL2021-05-20
59306SUPPL2019-07-10
59283SUPPL2019-07-09
47304SUPPL2017-02-24
9992SUPPL2014-10-16
40138SUPPL2014-10-15
9991SUPPL2014-06-18
19295SUPPL2014-06-17
43389ORIG2013-04-22
24409ORIG2013-04-22
19294ORIG2013-03-15
9990ORIG2013-03-15