Application 203284

Type
NDA
Sponsor
HORIZON THERAP

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001RAVICTIGLYCEROL PHENYLBUTYRATELIQUID;ORAL1.1GM/MLYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N203284-001RAVICTIGLYCEROL PHENYLBUTYRATE1.1GM/MLLIQUID / ORALAARLD, RS2013-02-01

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N203284-001AA

Orange Book patents#

Current patent rows page 1 of 1 · 14 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N203284-001100459582030-09-22U-18162018-08-22
N203284-001100459592030-09-22U-18162018-08-22
N203284-001101830022030-09-22U-18162019-02-21
N203284-001101830032030-09-22U-18162019-02-21
N203284-001101830042030-09-22U-18162019-02-21
N203284-001101830052030-09-22U-18162019-02-21
N203284-001101830062030-09-22U-18162019-02-21
N203284-001106680402030-09-22U-18162020-07-02
N203284-00186420122030-09-22U-13832014-02-27
N203284-00192542782030-09-22U-18162016-02-29
N203284-00193269662030-09-22U-18162016-05-25
N203284-00195611972030-09-22U-13832017-07-06
N203284-00199623592030-09-22U-18162018-06-07
N203284-00199996082030-09-22U-18162018-07-12

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N203284-001RAVICTI1.1GM/MLLIQUID / ORALAARLD, RS2013-02-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001RAVICTI1.1GM/MLLIQUID / ORALAARLD, RS2013-02-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-018072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-015c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-015d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-014b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-0174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N203284-001RAVICTI1.1GM/MLLIQUID / ORALAARLD, RS2013-02-01782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-0187673890dc5c…
2021-03-12 10:30 UTC2021-03N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-015aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-018869cabd3fbd…
2020-11-12 02:37 UTC2020-11N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01c0c555d07b60…
2019-12-14 00:12 UTC2019-12N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-013f01610625f2…
2019-09-15 20:21 UTC2019-09N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01b00525d2431f…
2019-07-19 19:46 UTC2019-07N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-016a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-011c564ffb4f44…
2023-12-20 04:57 UTC2023-12N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-019b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-013f0d92c62455…
2023-05-13 08:27 UTC2023-05N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01053a50430f4f…
2023-01-26 05:58 UTC2023-01N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-013bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-013a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N203284-001RAVICTI1.1GM/MLLIQUID / ORALRLD, RS2013-02-01cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N203284-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001AA131067a03dcf5…
2021-12-28 21:50 UTC2021-12N203284-001AA1782e0a99824c…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N203284-001AA1a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 16 · 634 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N203284-001100459582030-09-22U-18162018-08-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-001100459592030-09-22U-18162018-08-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-001101830022030-09-22U-18162019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-001101830032030-09-22U-18162019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-001101830042030-09-22U-18162019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-001101830052030-09-22U-18162019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-001101830062030-09-22U-18162019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-001106680402030-09-22U-18162020-07-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-00186420122030-09-22U-13832014-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-00192542782030-09-22U-18162016-02-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-00193269662030-09-22U-18162016-05-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-00195611972030-09-22U-13832017-07-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-00199623592030-09-22U-18162018-06-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-00199996082030-09-22U-18162018-07-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203284-00184042152032-03-09U-1383Delist requested2013-04-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001100459582030-09-22U-18162018-08-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001100459592030-09-22U-18162018-08-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001101830022030-09-22U-18162019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001101830032030-09-22U-18162019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001101830042030-09-22U-18162019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001101830052030-09-22U-18162019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001101830062030-09-22U-18162019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-001106680402030-09-22U-18162020-07-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-00186420122030-09-22U-13832014-02-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-00192542782030-09-22U-18162016-02-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-00193269662030-09-22U-18162016-05-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-00195611972030-09-22U-13832017-07-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-00199623592030-09-22U-18162018-06-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-00199996082030-09-22U-18162018-07-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203284-00184042152032-03-09U-1383Delist requested2013-04-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N203284-001100459582030-09-22U-18162018-08-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-001100459592030-09-22U-18162018-08-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-001101830022030-09-22U-18162019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-001101830032030-09-22U-18162019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-001101830042030-09-22U-18162019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-001101830052030-09-22U-18162019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-001101830062030-09-22U-18162019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-001106680402030-09-22U-18162020-07-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-00186420122030-09-22U-13832014-02-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203284-00192542782030-09-22U-18162016-02-296a471c1ec25d…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 48 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203284-001ODE-1572024-04-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203284-001ODE-1572024-04-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203284-001ODE-1572024-04-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203284-001ODE-1572024-04-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203284-001ODE-1572024-04-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203284-001ODE-1572024-04-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203284-001ODE-1572024-04-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203284-001ODE-1572024-04-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203284-001ODE-1572024-04-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203284-001ODE-1572024-04-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N203284-001ODE-1572024-04-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N203284-001ODE-1572024-04-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N203284-001ODE-422020-02-0174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N203284-001NPP2020-04-2874a2ff9319b5…
2019-12-13 00:20 UTC2019-12N203284-001ODE-1572024-04-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N203284-001ODE-1572024-04-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N203284-001NPP2021-12-21782e0a99824c…
2021-12-28 21:50 UTC2021-12N203284-001ODE-1572024-04-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203284-001ODE-1572024-04-2887673890dc5c…
2021-03-12 10:30 UTC2021-03N203284-001ODE-1572024-04-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N203284-001ODE-422020-02-018869cabd3fbd…
2020-12-22 03:56 UTC2020-12N203284-001NPP2020-04-288869cabd3fbd…
2020-12-22 03:56 UTC2020-12N203284-001ODE-1572024-04-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11N203284-001ODE-422020-02-01c0c555d07b60…
2020-11-12 02:37 UTC2020-11N203284-001NPP2020-04-28c0c555d07b60…
2020-11-12 02:37 UTC2020-11N203284-001ODE-1572024-04-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12N203284-001ODE-422020-02-013f01610625f2…
2019-12-14 00:12 UTC2019-12N203284-001NPP2020-04-283f01610625f2…
2019-12-14 00:12 UTC2019-12N203284-001ODE-1572024-04-283f01610625f2…
2019-09-15 20:21 UTC2019-09N203284-001ODE-422020-02-01b00525d2431f…
2019-09-15 20:21 UTC2019-09N203284-001NPP2020-04-28b00525d2431f…
2019-09-15 20:21 UTC2019-09N203284-001ODE-1572024-04-28b00525d2431f…
2019-07-19 19:46 UTC2019-07N203284-001ODE-422020-02-01ea99ee380514…
2019-07-19 19:46 UTC2019-07N203284-001NPP2020-04-28ea99ee380514…
2019-07-19 19:46 UTC2019-07N203284-001ODE-1572024-04-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203284-001ODE-1572024-04-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203284-001ODE-1572024-04-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12N203284-001ODE-1572024-04-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N203284-001ODE-1572024-04-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N203284-001ODE-1572024-04-289b2671bbb829…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
RavictiGLYCEROL PHENYLBUTYRATEHorizon Therapeutics USA, Inc.900e7dc0-9afe-4f50-80de-90567bb785192025-10-29Warnings, Adverse reactionsExact identifier
application applno (NDA): 203284
application number: NDA203284
ndc (product): 75987-050
glycerol phenylbutyrateGLYCEROL PHENYLBUTYRATELupin Pharmaceuticals, Inc.9bfa912f-c86c-4702-ac99-464c4356d80c2025-06-30Warnings, Adverse reactionsExact identifier
application applno (NDA): 203284
application number: NDA203284

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 4 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
75987-050Ravictiglycerol phenylbutyrateHorizon Therapeutics, Inc.NDACurrent
75987-050Ravictiglycerol phenylbutyrateHorizon Therapeutics, Inc.NDACurrent
75987-050Ravictiglycerol phenylbutyrateHorizon Therapeutics, Inc.NDACurrent
75987-050Ravictiglycerol phenylbutyrateHorizon Therapeutics, LLC.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
68580SUPPL2021-09-10
68577SUPPL2021-09-10
68551SUPPL2021-09-08
60482SUPPL2019-10-09
60252SUPPL2019-10-07
60251SUPPL2019-10-07
57063SUPPL2018-12-30
57029SUPPL2018-12-26
57028SUPPL2018-12-26
48283SUPPL2017-05-08
48181SUPPL2017-05-02
48174SUPPL2017-05-01
45291SUPPL2016-09-12
45266SUPPL2016-09-09
10194SUPPL2014-07-08
40285SUPPL2014-07-03
22919ORIG2013-03-28
40284ORIG2013-02-06
32405ORIG2013-02-04