Application 205098

Type
NDA
Sponsor
PROVENSIS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001VARITHENAPOLIDOCANOLSOLUTION;INTRAVENOUS180MG/18ML (10MG/ML)YesYes
002VARITHENAPOLIDOCANOLSOLUTION;INTRAVENOUS77.5MG/7.75ML (10MG/ML)YesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N205098-001VARITHENAPOLIDOCANOL180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25
N205098-002VARITHENAPOLIDOCANOL77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21

Orange Book patents#

Current patent rows page 1 of 1 · 2 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N205098-00178149432027-11-19U-1461Drug product
N205098-00194806522032-05-12Drug product2016-11-30

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25caaa826d4ba7…
2026-08-18 06:07:402026-07N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25d06236e962d9…
2024-10-29 15:01 UTC2024-10N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-211e350fbaab3a…
2024-05-31 18:47 UTC2024-05N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-258072bd15b7f6…
2024-05-31 18:47 UTC2024-05N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD2017-12-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2017-12-215c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2017-12-215d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2017-12-214b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-2574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2017-12-2174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N205098-001VARITHENA180MG/18ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2013-11-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N205098-002VARITHENA77.5MG/7.75ML (10MG/ML)SOLUTION / INTRAVENOUSRLD, RS2017-12-21bb7c543d1eb4…

Observed Orange Book patent history#

Patent history page 1 of 6 · 226 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N205098-00178149432027-11-19U-1461Drug productcaaa826d4ba7…
2026-08-18 06:07:402026-07N205098-00194806522032-05-12Drug product2016-11-30caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N205098-00178149432027-11-19U-1461Drug product011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205098-00194806522032-05-12Drug product2016-11-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205098-00178149432027-11-19U-1461Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205098-00194806522032-05-12Drug product2016-11-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08N205098-00178149432027-11-19U-1461Drug product6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205098-00194806522032-05-12Drug product2016-11-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205098-00178149432027-11-19U-1461Drug productfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205098-00194806522032-05-12Drug product2016-11-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205098-00178149432027-11-19U-1461Drug productb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205098-00194806522032-05-12Drug product2016-11-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205098-00181229172024-09-09Drug product03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205098-00177319862024-11-17U-1463Drug substance, Drug product03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205098-00178149432027-11-19U-1461Drug product03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205098-00194806522032-05-12Drug product2016-11-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205098-00181229172024-09-09Drug product2680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205098-00177319862024-11-17U-1463Drug substance, Drug product2680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205098-00178149432027-11-19U-1461Drug product2680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205098-00194806522032-05-12Drug product2016-11-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205098-00181229172024-09-09Drug product5bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205098-00177319862024-11-17U-1463Drug substance, Drug product5bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205098-00178149432027-11-19U-1461Drug product5bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205098-00194806522032-05-12Drug product2016-11-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205098-00181229172024-09-09Drug productd8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205098-00177319862024-11-17U-1463Drug substance, Drug productd8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205098-00178149432027-11-19U-1461Drug productd8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205098-00194806522032-05-12Drug product2016-11-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205098-00181229172024-09-09Drug productd06236e962d9…
2024-10-29 15:01 UTC2024-10N205098-00177319862024-11-17U-1463Drug substance, Drug productd06236e962d9…
2024-10-29 15:01 UTC2024-10N205098-00178149432027-11-19U-1461Drug productd06236e962d9…
2024-10-29 15:01 UTC2024-10N205098-00194806522032-05-12Drug product2016-11-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205098-00181229172024-09-09Drug product79d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205098-00177319862024-11-17U-1463Drug substance, Drug product79d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205098-00178149432027-11-19U-1461Drug product79d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205098-00194806522032-05-12Drug product2016-11-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205098-00181229172024-09-09Drug product301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205098-00177319862024-11-17U-1463Drug substance, Drug product301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205098-00178149432027-11-19U-1461Drug product301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205098-00194806522032-05-12Drug product2016-11-30301d65b070ca…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
VarithenaPOLIDOCANOLBoston Scientific Corporationdfd6b4a0-b0dc-11e2-9e96-0800200c9a662026-08-07Warnings, Adverse reactionsExact identifier
application applno (NDA): 205098
application number: NDA205098
ndc (product): 60635-123
ndc (product): 60635-133
ndc (product): 60635-118

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 19 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
60635-107VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-107VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-107VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-107VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-111VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-111VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-111VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-111VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-118VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-118VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-118VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-118VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-118VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-123VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-133VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-133VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-133VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-133VarithenapolidocanolBiocompatibles, Inc.NDACurrent
60635-133VarithenapolidocanolBiocompatibles, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
59811SUPPL2019-08-22
59801SUPPL2019-08-22
50922SUPPL2017-12-27
50921SUPPL2017-12-27
40443SUPPL2016-06-27
32629SUPPL2016-06-24
40442SUPPL2015-01-12
10425SUPPL2015-01-09
44913ORIG2014-07-28
43484ORIG2014-07-28
19623SUPPL2014-07-03
10424SUPPL2014-06-27
10423ORIG2013-11-27
40441ORIG2013-11-26