Application 215559

Type
NDA
Sponsor
IPSEN

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001SOHONOSPALOVAROTENECAPSULE;ORAL1MGYesNo
002SOHONOSPALOVAROTENECAPSULE;ORAL1.5MGYesNo
003SOHONOSPALOVAROTENECAPSULE;ORAL2.5MGYesNo
004SOHONOSPALOVAROTENECAPSULE;ORAL5MGYesNo
005SOHONOSPALOVAROTENECAPSULE;ORAL10MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 5 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N215559-001SOHONOSPALOVAROTENE1MGCAPSULE / ORALRLD2023-08-16
N215559-002SOHONOSPALOVAROTENE1.5MGCAPSULE / ORALRLD2023-08-16
N215559-003SOHONOSPALOVAROTENE2.5MGCAPSULE / ORALRLD2023-08-16
N215559-004SOHONOSPALOVAROTENE5MGCAPSULE / ORALRLD2023-08-16
N215559-005SOHONOSPALOVAROTENE10MGCAPSULE / ORALRLD, RS2023-08-16

Orange Book patents#

Current patent rows page 1 of 1 · 45 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N215559-001102929542031-08-31U-36762023-09-07
N215559-001120233122031-08-31U-39662024-07-25
N215559-00193144392031-08-31U-36762023-09-07
N215559-00197890742031-08-31U-36762023-09-07
N215559-001108641942037-06-08U-36762023-09-07
N215559-001116229592037-06-08U-36762023-09-07
N215559-001121382452037-06-08U-40312024-11-15
N215559-001122016142037-06-08U-40312025-02-07
N215559-001124586262037-06-08U-36762025-12-03
N215559-002102929542031-08-31U-36762023-09-07
N215559-002120233122031-08-31U-39662024-07-25
N215559-00293144392031-08-31U-36762023-09-07
N215559-00297890742031-08-31U-36762023-09-07
N215559-002108641942037-06-08U-36762023-09-07
N215559-002116229592037-06-08U-36762023-09-07
N215559-002121382452037-06-08U-40312024-11-15
N215559-002122016142037-06-08U-40312025-02-07
N215559-002124586262037-06-08U-36762025-12-03
N215559-003102929542031-08-31U-36762023-09-07
N215559-003120233122031-08-31U-39662024-07-25
N215559-00393144392031-08-31U-36762023-09-07
N215559-00397890742031-08-31U-36762023-09-07
N215559-003108641942037-06-08U-36762023-09-07
N215559-003116229592037-06-08U-36762023-09-07
N215559-003121382452037-06-08U-40312024-11-15
N215559-003122016142037-06-08U-40312025-02-07
N215559-003124586262037-06-08U-36762025-12-03
N215559-004102929542031-08-31U-36762023-09-07
N215559-004120233122031-08-31U-39662024-07-25
N215559-00493144392031-08-31U-36762023-09-07
N215559-00497890742031-08-31U-36762023-09-07
N215559-004108641942037-06-08U-36762023-09-07
N215559-004116229592037-06-08U-36762023-09-07
N215559-004121382452037-06-08U-40312024-11-15
N215559-004122016142037-06-08U-40312025-02-07
N215559-004124586262037-06-08U-36762025-12-03
N215559-005102929542031-08-31U-36762023-09-07
N215559-005120233122031-08-31U-39662024-07-25
N215559-00593144392031-08-31U-36762023-09-07
N215559-00597890742031-08-31U-36762023-09-07
N215559-005108641942037-06-08U-36762023-09-07
N215559-005116229592037-06-08U-36762023-09-07
N215559-005121382452037-06-08U-40312024-11-15
N215559-005122016142037-06-08U-40312025-02-07
N215559-005124586262037-06-08U-36762025-12-03

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 10 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N215559-001NCE2028-08-16
N215559-001ODE-4392030-08-16
N215559-002NCE2028-08-16
N215559-002ODE-4392030-08-16
N215559-003NCE2028-08-16
N215559-003ODE-4392030-08-16
N215559-004NCE2028-08-16
N215559-004ODE-4392030-08-16
N215559-005NCE2028-08-16
N215559-005ODE-4392030-08-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 100 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215559-001SOHONOS1MGCAPSULE / ORALRLD2023-08-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215559-002SOHONOS1.5MGCAPSULE / ORALRLD2023-08-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215559-003SOHONOS2.5MGCAPSULE / ORALRLD2023-08-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215559-004SOHONOS5MGCAPSULE / ORALRLD2023-08-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215559-005SOHONOS10MGCAPSULE / ORALRLD, RS2023-08-165bbf6a4d5a75…

Observed Orange Book patent history#

Patent history page 1 of 16 · 640 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215559-001102929542031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-001120233122031-08-31U-39662024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00193144392031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00197890742031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-001108641942037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-001116229592037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-001121382452037-06-08U-40312024-11-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-001122016142037-06-08U-40312025-02-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-001124586262037-06-08U-36762025-12-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002102929542031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002120233122031-08-31U-39662024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00293144392031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00297890742031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002108641942037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002116229592037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002121382452037-06-08U-40312024-11-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002122016142037-06-08U-40312025-02-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002124586262037-06-08U-36762025-12-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003102929542031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003120233122031-08-31U-39662024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00393144392031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00397890742031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003108641942037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003116229592037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003121382452037-06-08U-40312024-11-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003122016142037-06-08U-40312025-02-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003124586262037-06-08U-36762025-12-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004102929542031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004120233122031-08-31U-39662024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00493144392031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00497890742031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004108641942037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004116229592037-06-08U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004121382452037-06-08U-40312024-11-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004122016142037-06-08U-40312025-02-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004124586262037-06-08U-36762025-12-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-005102929542031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-005120233122031-08-31U-39662024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00593144392031-08-31U-36762023-09-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-00597890742031-08-31U-36762023-09-07011fe1cb6892…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 5 · 200 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N215559-001NCE2028-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-001ODE-4392030-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002NCE2028-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-002ODE-4392030-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003NCE2028-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-003ODE-4392030-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004NCE2028-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-004ODE-4392030-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-005NCE2028-08-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215559-005ODE-4392030-08-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-001NCE2028-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-001ODE-4392030-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-002NCE2028-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-002ODE-4392030-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-003NCE2028-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-003ODE-4392030-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-004NCE2028-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-004ODE-4392030-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-005NCE2028-08-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215559-005ODE-4392030-08-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N215559-001NCE2028-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-001ODE-4392030-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-002NCE2028-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-002ODE-4392030-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-003NCE2028-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-003ODE-4392030-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-004NCE2028-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-004ODE-4392030-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-005NCE2028-08-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215559-005ODE-4392030-08-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-001NCE2028-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-001ODE-4392030-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-002NCE2028-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-002ODE-4392030-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-003NCE2028-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-003ODE-4392030-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-004NCE2028-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-004ODE-4392030-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-005NCE2028-08-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215559-005ODE-4392030-08-16fd3edfee7708…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
SOHONOSPALOVAROTENEIpsen Biopharmaceuticals, Inc.67dce406-7cc4-4d66-92de-ad18b6df06252025-03-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 215559
application number: NDA215559

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
81607SUPPL 2025-03-17
81596SUPPL 2025-03-17
81595SUPPL 2025-03-17
75489ORIG 2023-09-15
75111ORIG 2023-08-17
75108ORIG 2023-08-17