Application 216354

Type
NDA
Sponsor
TEVA

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL6MGYesNo
002AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL12MGYesNo
003AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL24MGYesNo
004AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL30MGYesNo
005AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL36MGYesNo
006AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL42MGYesNo
007AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL48MGYesYes
008AUSTEDO XRDEUTETRABENAZINETABLET, EXTENDED RELEASE;ORAL18MGYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 8 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N216354-001AUSTEDO XRDEUTETRABENAZINE6MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17
N216354-002AUSTEDO XRDEUTETRABENAZINE12MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17
N216354-003AUSTEDO XRDEUTETRABENAZINE24MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17
N216354-004AUSTEDO XRDEUTETRABENAZINE30MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29
N216354-005AUSTEDO XRDEUTETRABENAZINE36MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29
N216354-006AUSTEDO XRDEUTETRABENAZINE42MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29
N216354-007AUSTEDO XRDEUTETRABENAZINE48MGTABLET, EXTENDED RELEASE / ORALRLD, RS2024-05-29
N216354-008AUSTEDO XRDEUTETRABENAZINE18MGTABLET, EXTENDED RELEASE / ORALRLD2024-07-01

Orange Book patents#

Current patent rows page 1 of 3 · 240 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N216354-00185247332031-04-03Drug substance, Drug product2023-02-27
N216354-0018524733*PED2031-10-03Pediatric extension
N216354-00195507802033-09-18U-1995Drug substance, Drug product2023-02-27
N216354-00195507802033-09-18U-3055Drug substance, Drug product2023-02-27
N216354-0019550780*PED2034-03-18Pediatric extension
N216354-001109599962036-03-07U-30552023-02-27
N216354-001113577722036-03-07U-19952023-02-27
N216354-001113577722036-03-07U-30552023-02-27
N216354-001114462912036-03-07U-19952023-02-27
N216354-001115649172036-03-07U-19952023-02-27
N216354-001116482442036-03-07U-19952023-06-05
N216354-001120168582036-03-07U-19952024-07-25
N216354-001120168582036-03-07U-30552024-07-25
N216354-00110959996*PED2036-09-07Pediatric extension
N216354-00111357772*PED2036-09-07Pediatric extension
N216354-00111446291*PED2036-09-07Pediatric extension
N216354-00111564917*PED2036-09-07Pediatric extension
N216354-00111648244*PED2036-09-07Pediatric extension
N216354-00112016858*PED2036-09-07Pediatric extension
N216354-001111793862038-03-15U-1995Drug product2023-02-27
N216354-001111793862038-03-15U-3055Drug product2023-02-27
N216354-001118132322038-03-15Drug product2023-12-07
N216354-00111179386*PED2038-09-15Pediatric extension
N216354-00111813232*PED2038-09-15Pediatric extension
N216354-001113114882041-06-10U-1995Drug product2023-02-27
N216354-001113114882041-06-10U-3055Drug product2023-02-27
N216354-001125890752041-06-10U-19952026-04-29
N216354-001125890752041-06-10U-30552026-04-29
N216354-001125995982041-06-10U-19952026-04-29
N216354-001125995982041-06-10U-30552026-04-29
N216354-00285247332031-04-03Drug substance, Drug product2023-02-27
N216354-0028524733*PED2031-10-03Pediatric extension
N216354-00295507802033-09-18U-1995Drug substance, Drug product2023-02-27
N216354-00295507802033-09-18U-3055Drug substance, Drug product2023-02-27
N216354-0029550780*PED2034-03-18Pediatric extension
N216354-002109599962036-03-07U-30552023-02-27
N216354-002113577722036-03-07U-19952023-02-27
N216354-002113577722036-03-07U-30552023-02-27
N216354-002114462912036-03-07U-19952023-02-27
N216354-002115649172036-03-07U-19952023-02-27
N216354-002116482442036-03-07U-19952023-06-05
N216354-002120168582036-03-07U-19952024-07-25
N216354-002120168582036-03-07U-30552024-07-25
N216354-00210959996*PED2036-09-07Pediatric extension
N216354-00211357772*PED2036-09-07Pediatric extension
N216354-00211446291*PED2036-09-07Pediatric extension
N216354-00211564917*PED2036-09-07Pediatric extension
N216354-00211648244*PED2036-09-07Pediatric extension
N216354-00212016858*PED2036-09-07Pediatric extension
N216354-002111793862038-03-15U-1995Drug product2023-02-27
N216354-002111793862038-03-15U-3055Drug product2023-02-27
N216354-002118132322038-03-15Drug product2023-12-07
N216354-00211179386*PED2038-09-15Pediatric extension
N216354-00211813232*PED2038-09-15Pediatric extension
N216354-002113114882041-06-10U-1995Drug product2023-02-27
N216354-002113114882041-06-10U-3055Drug product2023-02-27
N216354-002125890752041-06-10U-19952026-04-29
N216354-002125890752041-06-10U-30552026-04-29
N216354-002125995982041-06-10U-19952026-04-29
N216354-002125995982041-06-10U-30552026-04-29
N216354-00385247332031-04-03Drug substance, Drug product2023-02-27
N216354-0038524733*PED2031-10-03Pediatric extension
N216354-00395507802033-09-18U-1995Drug substance, Drug product2023-02-27
N216354-00395507802033-09-18U-3055Drug substance, Drug product2023-02-27
N216354-0039550780*PED2034-03-18Pediatric extension
N216354-003109599962036-03-07U-30552023-02-27
N216354-003113577722036-03-07U-19952023-02-27
N216354-003113577722036-03-07U-30552023-02-27
N216354-003114462912036-03-07U-19952023-02-27
N216354-003115649172036-03-07U-19952023-02-27
N216354-003116482442036-03-07U-19952023-06-05
N216354-003120168582036-03-07U-19952024-07-25
N216354-003120168582036-03-07U-30552024-07-25
N216354-00310959996*PED2036-09-07Pediatric extension
N216354-00311357772*PED2036-09-07Pediatric extension
N216354-00311446291*PED2036-09-07Pediatric extension
N216354-00311564917*PED2036-09-07Pediatric extension
N216354-00311648244*PED2036-09-07Pediatric extension
N216354-00312016858*PED2036-09-07Pediatric extension
N216354-003111793862038-03-15U-1995Drug product2023-02-27

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 137 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N216354-001AUSTEDO XR6MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002AUSTEDO XR12MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-003AUSTEDO XR24MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-004AUSTEDO XR30MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-005AUSTEDO XR36MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-006AUSTEDO XR42MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-007AUSTEDO XR48MGTABLET, EXTENDED RELEASE / ORALRLD, RS2024-05-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-008AUSTEDO XR18MGTABLET, EXTENDED RELEASE / ORALRLD2024-07-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-001AUSTEDO XR6MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-002AUSTEDO XR12MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-003AUSTEDO XR24MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-004AUSTEDO XR30MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-005AUSTEDO XR36MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-006AUSTEDO XR42MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-007AUSTEDO XR48MGTABLET, EXTENDED RELEASE / ORALRLD, RS2024-05-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216354-008AUSTEDO XR18MGTABLET, EXTENDED RELEASE / ORALRLD2024-07-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N216354-001AUSTEDO XR6MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216354-002AUSTEDO XR12MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216354-003AUSTEDO XR24MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216354-004AUSTEDO XR30MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216354-005AUSTEDO XR36MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216354-006AUSTEDO XR42MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216354-007AUSTEDO XR48MGTABLET, EXTENDED RELEASE / ORALRLD, RS2024-05-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216354-008AUSTEDO XR18MGTABLET, EXTENDED RELEASE / ORALRLD2024-07-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-001AUSTEDO XR6MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-002AUSTEDO XR12MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-003AUSTEDO XR24MGTABLET, EXTENDED RELEASE / ORALRLD, RS2023-02-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-004AUSTEDO XR30MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-005AUSTEDO XR36MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-006AUSTEDO XR42MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-007AUSTEDO XR48MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216354-008AUSTEDO XR18MGTABLET, EXTENDED RELEASE / ORALRLD2024-07-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-001AUSTEDO XR6MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-002AUSTEDO XR12MGTABLET, EXTENDED RELEASE / ORALRLD2023-02-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-003AUSTEDO XR24MGTABLET, EXTENDED RELEASE / ORALRLD, RS2023-02-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-004AUSTEDO XR30MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-005AUSTEDO XR36MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-006AUSTEDO XR42MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-007AUSTEDO XR48MGTABLET, EXTENDED RELEASE / ORALRLD2024-05-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216354-008AUSTEDO XR18MGTABLET, EXTENDED RELEASE / ORALRLD2024-07-01b8a1b40f171c…

Observed Orange Book patent history#

Patent history page 1 of 80 · 3,171 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N216354-00185247332031-04-03Drug substance, Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-0018524733*PED2031-10-03Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00195507802033-09-18U-1995Drug substance, Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00195507802033-09-18U-3055Drug substance, Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-0019550780*PED2034-03-18Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001109599962036-03-07U-30552023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001113577722036-03-07U-19952023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001113577722036-03-07U-30552023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001114462912036-03-07U-19952023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001115649172036-03-07U-19952023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001116482442036-03-07U-19952023-06-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001120168582036-03-07U-19952024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001120168582036-03-07U-30552024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00110959996*PED2036-09-07Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00111357772*PED2036-09-07Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00111446291*PED2036-09-07Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00111564917*PED2036-09-07Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00111648244*PED2036-09-07Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00112016858*PED2036-09-07Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001111793862038-03-15U-1995Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001111793862038-03-15U-3055Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001118132322038-03-15Drug product2023-12-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00111179386*PED2038-09-15Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00111813232*PED2038-09-15Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001113114882041-06-10U-1995Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-001113114882041-06-10U-3055Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00285247332031-04-03Drug substance, Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-0028524733*PED2031-10-03Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00295507802033-09-18U-3055Drug substance, Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00295507802033-09-18U-1995Drug substance, Drug product2023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-0029550780*PED2034-03-18Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002109599962036-03-07U-30552023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002113577722036-03-07U-30552023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002113577722036-03-07U-19952023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002114462912036-03-07U-19952023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002115649172036-03-07U-19952023-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002116482442036-03-07U-19952023-06-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002120168582036-03-07U-30552024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-002120168582036-03-07U-19952024-07-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216354-00210959996*PED2036-09-07Pediatric extension011fe1cb6892…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AustedoDEUTETRABENAZINETeva Neuroscience, Inc.7ea3c60a-45c7-44cc-afc2-d87fa53993c02025-02-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 216354
application number: NDA216354

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
82376SUPPL 2025-06-02
81411SUPPL 2025-03-03
81410SUPPL 2025-03-03
78985SUPPL 2024-07-08
78963SUPPL 2024-07-02
78780SUPPL 2024-05-31
78582SUPPL 2024-05-30
77303ORIG 2024-01-26
73579ORIG 2023-02-21
73559ORIG 2023-02-17