Application 217514

Type
NDA
Sponsor
NOVARTIS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001TAFINLARDABRAFENIB MESYLATETABLET, FOR SUSPENSION;ORALEQ 10MG BASEYesYes
002TAFINLARDABRAFENIB MESYLATECAPSULE;ORAL75MGNoNo
003TAFINLARDABRAFENIB MESYLATETABLET; ORAL SUSPENSION10MGNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N217514-001TAFINLARDABRAFENIB MESYLATEEQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N217514-00179941852030-01-20Drug substance, Drug product2023-05-04
N217514-00184153452030-01-20Drug substance, Drug product2023-05-04
N217514-0017994185*PED2030-07-20Pediatric extension
N217514-0018415345*PED2030-07-20Pediatric extension
N217514-00187037812030-10-15U-3565Drug substance, Drug product2023-05-04
N217514-0018703781*PED2031-04-15Pediatric extension
N217514-001115043332038-06-29Drug product2023-05-04
N217514-00111504333*PED2038-12-29Pediatric extension

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 4 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N217514-001NP2026-03-16
N217514-001PED2026-09-16
N217514-001ODE-4282030-03-16
N217514-001PED2030-09-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-1679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-161e350fbaab3a…
2024-05-31 18:47 UTC2024-05N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-168072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-166a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-161c564ffb4f44…
2023-12-20 04:57 UTC2023-12N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-169b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-163f0d92c62455…
2023-05-13 08:27 UTC2023-05N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16053a50430f4f…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N217514-001TAFINLAREQ 10MG BASETABLET, FOR SUSPENSION / ORALRLD, RS2023-03-16a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 5 · 186 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N217514-00179941852030-01-20Drug substance, Drug product2023-05-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-00184153452030-01-20Drug substance, Drug product2023-05-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-0017994185*PED2030-07-20Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-0018415345*PED2030-07-20Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-00187037812030-10-15U-3565Drug substance, Drug product2023-05-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-0018703781*PED2031-04-15Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-001115043332038-06-29Drug product2023-05-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-00111504333*PED2038-12-29Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-00188354432025-06-10U-35652023-05-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-0018835443*PED2025-12-10Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-00179941852030-01-20Drug substance, Drug product2023-05-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-00184153452030-01-20Drug substance, Drug product2023-05-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-0017994185*PED2030-07-20Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-0018415345*PED2030-07-20Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-00187037812030-10-15U-3565Drug substance, Drug product2023-05-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-0018703781*PED2031-04-15Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-001115043332038-06-29Drug product2023-05-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-00111504333*PED2038-12-29Pediatric extension31067a03dcf5…
2025-08-23 18:47 UTC2025-08N217514-00188354432025-06-10U-35652023-05-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-0018835443*PED2025-12-10Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-00179941852030-01-20Drug substance, Drug product2023-05-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-00184153452030-01-20Drug substance, Drug product2023-05-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-0017994185*PED2030-07-20Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-0018415345*PED2030-07-20Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-00187037812030-10-15U-3565Drug substance, Drug product2023-05-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-0018703781*PED2031-04-15Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-001115043332038-06-29Drug product2023-05-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-00111504333*PED2038-12-29Pediatric extension6a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-00188354432025-06-10U-35652023-05-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-0018835443*PED2025-12-10Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-00179941852030-01-20Drug substance, Drug product2023-05-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-00184153452030-01-20Drug substance, Drug product2023-05-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-0017994185*PED2030-07-20Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-0018415345*PED2030-07-20Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-00187037812030-10-15U-3565Drug substance, Drug product2023-05-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-0018703781*PED2031-04-15Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-001115043332038-06-29Drug product2023-05-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-00111504333*PED2038-12-29Pediatric extensionfd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N217514-00188354432025-06-10U-35652023-05-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N217514-0018835443*PED2025-12-10Pediatric extensionb8a1b40f171c…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 76 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N217514-001NP2026-03-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-001PED2026-09-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-001ODE-4282030-03-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N217514-001PED2030-09-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-001NP2026-03-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-001PED2026-09-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-001ODE-4282030-03-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N217514-001PED2030-09-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N217514-001NP2026-03-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-001PED2026-09-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-001ODE-4282030-03-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N217514-001PED2030-09-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-001NP2026-03-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-001PED2026-09-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-001ODE-4282030-03-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N217514-001PED2030-09-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N217514-001NP2026-03-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N217514-001PED2026-09-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N217514-001ODE-4282030-03-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N217514-001PED2030-09-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N217514-001NP2026-03-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N217514-001PED2026-09-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N217514-001ODE-4282030-03-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N217514-001PED2030-09-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N217514-001NP2026-03-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N217514-001PED2026-09-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N217514-001ODE-4282030-03-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N217514-001PED2030-09-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N217514-001NP2026-03-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N217514-001PED2026-09-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N217514-001ODE-4282030-03-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N217514-001PED2030-09-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N217514-001NP2026-03-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N217514-001PED2026-09-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N217514-001ODE-4282030-03-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N217514-001PED2030-09-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N217514-001NP2026-03-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N217514-001PED2026-09-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N217514-001ODE-4282030-03-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N217514-001PED2030-09-16d06236e962d9…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TafinlarDABRAFENIBNovartis Pharmaceuticals Corporationfee1e6b1-e1a5-4254-9f2e-a70e0f8dbdea2026-05-20Warnings, Adverse reactionsExact identifier
application applno (NDA): 217514
application number: NDA217514

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
85732SUPPL 2026-04-21
85590SUPPL 2026-03-30
81912SUPPL 2025-04-09
81839SUPPL 2025-04-08
81671SUPPL 2025-03-21
81670SUPPL 2025-03-21
81522SUPPL 2025-03-11
81515SUPPL 2025-03-11
81072SUPPL 2025-02-06
80971SUPPL 2025-02-05
79121SUPPL 2024-07-18
79056SUPPL 2024-07-12
78037SUPPL 2024-04-03
78026SUPPL 2024-04-01
77645SUPPL 2024-02-28
77639SUPPL 2024-02-28
74264ORIG 2023-05-16
73798ORIG 2023-03-17
73790ORIG 2023-03-17