EMEND

Product NDC: 0006-0462
11-digit product format: 000060462
Labeler code: 0006
Product ID: 0006-0462_428f7828-6d1c-438b-a17d-b4af0700c740
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: aprepitant
Dosage form: CAPSULE
Route: ORAL
Labeler: Merck Sharp & Dohme LLC
Application: NDA021549
Marketing category: NDA
Marketing start: 2003-03-26
Substance: APREPITANT
Active strength: 125 mg/1
Pharmacologic classes: Cytochrome P450 2C9 Inducers [MoA], Cytochrome P450 3A4 Inducers [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Neurokinin 1 Antagonists [MoA], Substance P/Neurokinin-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	0006-0462	0006-0462-06	D	Discontinued by firm		2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source date	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	`557ba5c1ecfa…`	`9c80585c8c6e…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N021549-001	EMEND	APREPITANT	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26
N021549-002	EMEND	APREPITANT	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26
N021549-003	EMEND	APREPITANT	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
N021549-001	AB
N021549-002	AB

Orange Book patents#

Current patent rows page 1 of 1 · 6 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27
N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27
N021549-002	8258132	2027-09-26	U-1743	Drug product
N021549-002	8258132	2027-09-26	U-901	Drug product
N021549-003	8258132	2027-09-26	U-1743	Drug product
N021549-003	8258132	2027-09-26	U-901	Drug product

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-08-18 06:07:40	2026-07	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`1e350fbaab3a…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 86 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-08-18 06:07:40	2026-07	N021549-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N021549-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021549-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-002	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-002	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-002	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N021549-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021549-002	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-002	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-002	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021549-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021549-002	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N021549-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N021549-002	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N021549-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N021549-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N021549-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N021549-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N021549-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N021549-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N021549-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N021549-002	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N021549-001	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	N021549-002	AB	1	`bb7c543d1eb4…`

Observed Orange Book patent history#

Patent history page 1 of 7 · 252 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-08-18 06:07:40	2026-07	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	8258132	2027-09-26	U-901	Drug product		`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	8258132	2027-09-26	U-1743	Drug product		`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-003	8258132	2027-09-26	U-901	Drug product		`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-003	8258132	2027-09-26	U-1743	Drug product		`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	8258132	2027-09-26	U-901	Drug product		`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	8258132	2027-09-26	U-1743	Drug product		`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-003	8258132	2027-09-26	U-901	Drug product		`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-003	8258132	2027-09-26	U-1743	Drug product		`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	8258132	2027-09-26	U-901	Drug product		`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	8258132	2027-09-26	U-1743	Drug product		`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-003	8258132	2027-09-26	U-901	Drug product		`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-003	8258132	2027-09-26	U-1743	Drug product		`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	8258132	2027-09-26	U-901	Drug product		`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	8258132	2027-09-26	U-1743	Drug product		`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-003	8258132	2027-09-26	U-901	Drug product		`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-003	8258132	2027-09-26	U-1743	Drug product		`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	8258132	2027-09-26	U-901	Drug product		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	8258132	2027-09-26	U-1743	Drug product		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-003	8258132	2027-09-26	U-901	Drug product		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-003	8258132	2027-09-26	U-1743	Drug product		`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	8258132	2027-09-26	U-901	Drug product		`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	8258132	2027-09-26	U-1743	Drug product		`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-003	8258132	2027-09-26	U-901	Drug product		`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-003	8258132	2027-09-26	U-1743	Drug product		`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	8258132	2027-09-26	U-901	Drug product		`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	8258132	2027-09-26	U-1743	Drug product		`03ed91905a0d…`

Additional Listing Data#

Finished product: Yes
Brand name base: EMEND
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
APREPITANT	125 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1NF15YR6UY	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 10 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
403810	Internal RxNorm lookup
403811	Internal RxNorm lookup
404465	Internal RxNorm lookup
404466	Internal RxNorm lookup
644088	Internal RxNorm lookup
644278	Internal RxNorm lookup
754508	Internal RxNorm lookup
754509	Internal RxNorm lookup
1729308	Internal RxNorm lookup
1729311	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
696f9e80-9cae-403b-de9e-078343ce4713	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
2abc3e32-ae1f-4dec-be1c-0c39ac95b38e	Product name	7	20240514
5d352eda-d4de-4572-9a3f-32d6fd204f9a	Product name	1	20230911
3a5d67cc-4a03-45a3-8d74-5aeb67631be4	Product name	1	20230831
85fc66a9-58b2-e194-7cdb-89ff44dcf3e6	Product name	4	20210518
9f9a82fd-fcee-442f-9233-7f2d2f9f4568	Product name	1	20180108

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0006-0462-01	EMEND	6 in 1 BLISTER PACK	CAPSULE	6		42
0006-0462-06	EMEND	1 in 1 CARTON	CAPSULE	1		42

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0006-0462-01	EA - Each	0006-0462	9d4df6e9-f6af-4337-9a21-9541c0351571	1	2015-05-05
0006-0462-06	EA - Each	0006-0462	3a503cae-e103-4284-af96-a47a82137840	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
aprepitant	ACTIVE INGREDIENT	1NF15YR6UY	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
aprepitant	ACTIVE MOIETY	1NF15YR6UY	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
cellulose, microcrystalline	INACTIVE INGREDIENT	OP1R32D61U	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
ferric oxide red	INACTIVE INGREDIENT	1K09F3G675	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
ferric oxide yellow	INACTIVE INGREDIENT	EX438O2MRT	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
gelatin	INACTIVE INGREDIENT	2G86QN327L	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
hydroxypropyl cellulose (type H)	INACTIVE INGREDIENT	RFW2ET671P	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
silicon dioxide	INACTIVE INGREDIENT	ETJ7Z6XBU4	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
sucrose	INACTIVE INGREDIENT	C151H8M554	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24
titanium dioxide	INACTIVE INGREDIENT	15FIX9V2JP	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT [MERCK SHARP & DOHME CORP.]	24

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0006-0462	EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT EMEND (APREPITANT) POWDER, FOR SUSPENSION [MERCK SHARP & DOHME LLC]	41	Current NDC, Legacy NDC, 2 package rows	20240719_696f9e80-9cae-403b-de9e-078343ce4713.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
EMEND	APREPITANT	Merck Sharp & Dohme LLC	696f9e80-9cae-403b-de9e-078343ce4713	2024-07-05	Warnings, Adverse reactions	Exact identifier application applno (NDA): 021549 application number: NDA021549 ndc (product): 0006-0462

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
1NF15YR6UY	APREPITANT	170729-80-3	APREPITANT

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
754509	{1 (aprepitant 125 MG Oral Capsule [Emend]) / 2 (aprepitant 80 MG Oral Capsule [Emend]) } Pack [Emend Tri-Fold Pack]	BPCK	696f9e80-9cae-403b-de9e-078343ce4713	42
754508	{1 (aprepitant 125 MG Oral Capsule) / 2 (aprepitant 80 MG Oral Capsule) } Pack	GPCK	696f9e80-9cae-403b-de9e-078343ce4713	42
754508	aprepitant 125 MG (1), 80 MG (2) Oral Capsule 3 Count Pack	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
403811	aprepitant 125 MG Oral Capsule	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
1729308	aprepitant 125 MG Powder for Oral Suspension	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
644088	aprepitant 40 MG Oral Capsule	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
403810	aprepitant 80 MG Oral Capsule	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
404466	Emend 125 MG Oral Capsule	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
1729311	Emend 125 MG Powder for Oral Suspension	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
644278	Emend 40 MG Oral Capsule	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
404465	Emend 80 MG Oral Capsule	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
754509	Emend TriPack	PSN	696f9e80-9cae-403b-de9e-078343ce4713	42
404466	aprepitant 125 MG Oral Capsule [Emend]	SBD	696f9e80-9cae-403b-de9e-078343ce4713	42
1729311	aprepitant 125 MG Powder for Oral Suspension [Emend]	SBD	696f9e80-9cae-403b-de9e-078343ce4713	42
644278	aprepitant 40 MG Oral Capsule [Emend]	SBD	696f9e80-9cae-403b-de9e-078343ce4713	42
404465	aprepitant 80 MG Oral Capsule [Emend]	SBD	696f9e80-9cae-403b-de9e-078343ce4713	42
403811	aprepitant 125 MG Oral Capsule	SCD	696f9e80-9cae-403b-de9e-078343ce4713	42
1729308	aprepitant 125 MG Powder for Oral Suspension	SCD	696f9e80-9cae-403b-de9e-078343ce4713	42
644088	aprepitant 40 MG Oral Capsule	SCD	696f9e80-9cae-403b-de9e-078343ce4713	42
403810	aprepitant 80 MG Oral Capsule	SCD	696f9e80-9cae-403b-de9e-078343ce4713	42
404466	Emend 125 MG Oral Capsule	SY	696f9e80-9cae-403b-de9e-078343ce4713	42
1729311	Emend 125 MG Powder for Oral Suspension	SY	696f9e80-9cae-403b-de9e-078343ce4713	42
644278	Emend 40 MG Oral Capsule	SY	696f9e80-9cae-403b-de9e-078343ce4713	42
404465	Emend 80 MG Oral Capsule	SY	696f9e80-9cae-403b-de9e-078343ce4713	42
754509	Emend Tri-Fold Pack	SY	696f9e80-9cae-403b-de9e-078343ce4713	42

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Status
0006-0462-01	00006046201	6 in 1 BLISTER PACK	Historical
0006-0462-06	00006046206	1 in 1 CARTON	Historical