EMEND

Product NDC: 42254-160
11-digit product format: 422540160
Labeler code: 42254
Product ID: 42254-160_ec44482e-6194-4829-a3f7-ebe8d48a41a5
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: aprepitant
Dosage form: CAPSULE
Route: ORAL
Labeler: Rebel Distributors Corp
Application: NDA021549
Marketing category: NDA
Marketing start: 2003-03-26
Marketing end: 0000-00-00
Substance: APREPITANT
Active strength: 40 mg/1
Pharmacologic classes: Neurokinin 1 Antagonists [MoA],Substance P/Neurokinin-1 Receptor Antagonist [EPC],Cytochrome P450 3A4 Inhibitors [MoA],Cytochrome P450 2C9 Inducers [MoA],Cytochrome P450 3A4 Inducers [MoA]
NDC exclude flag: E
Listing certified through: 2017-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded product	product	42254-160		I	Inactivated by FDA		2026-08-17
excluded package	package	42254-160	42254-160-01	I	Inactivated by FDA		2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 44 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	42254-160-01	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	42254-160-01	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	42254-160-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	42254-160-01	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	42254-160-01	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	42254-160-01	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	42254-160-01	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	42254-160-01	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	42254-160-01	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	42254-160-01	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	42254-160-01	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	42254-160-01	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	42254-160-01	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	42254-160-01	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	42254-160-01	`1332a3947898…`	`d4bfe170f9cd…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded product	product		`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	42254-160-01	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded product	product		`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	42254-160-01	`86f5da6cb304…`	`a595104c45d7…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded product	product		`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	42254-160-01	`bd6a592717d7…`	`303034d00443…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded product	product		`8dfbde2a14a4…`	`c9ff85d89658…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded package	package	42254-160-01	`8dfbde2a14a4…`	`c9ff85d89658…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded product	product		`e2bbac7714bc…`	`27bdfed8d636…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded package	package	42254-160-01	`e2bbac7714bc…`	`27bdfed8d636…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded product	product		`9bebd1f3094a…`	`5416666fcb17…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded package	package	42254-160-01	`9bebd1f3094a…`	`5416666fcb17…`
2019-12-08 06:16 UTC · source 2019-12-05	excluded product	product		`110d247fa046…`	`a55b01930146…`
2019-12-08 06:16 UTC · source 2019-12-05	excluded package	package	42254-160-01	`110d247fa046…`	`a55b01930146…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N021549-001	EMEND	APREPITANT	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26
N021549-002	EMEND	APREPITANT	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26
N021549-003	EMEND	APREPITANT	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
N021549-001	AB
N021549-002	AB

Orange Book patents#

Current patent rows page 1 of 1 · 6 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27
N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27
N021549-002	8258132	2027-09-26	U-1743	Drug product
N021549-002	8258132	2027-09-26	U-901	Drug product
N021549-003	8258132	2027-09-26	U-1743	Drug product
N021549-003	8258132	2027-09-26	U-901	Drug product

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-08-18 06:07:40	2026-07	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-002	EMEND	125MG	CAPSULE / ORAL	AB	RLD, RS	2003-03-26	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-003	EMEND	40MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	CAPSULE / ORAL		RLD	2006-06-30	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021549-001	EMEND	80MG	CAPSULE / ORAL	AB	RLD	2003-03-26	`1e350fbaab3a…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 86 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-08-18 06:07:40	2026-07	N021549-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N021549-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021549-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021549-002	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021549-002	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021549-002	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N021549-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021549-002	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021549-002	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021549-002	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021549-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021549-002	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N021549-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N021549-002	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N021549-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N021549-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N021549-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N021549-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N021549-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N021549-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N021549-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N021549-002	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N021549-001	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	N021549-002	AB	1	`bb7c543d1eb4…`

Observed Orange Book patent history#

Patent history page 1 of 7 · 252 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-08-18 06:07:40	2026-07	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	8258132	2027-09-26	U-901	Drug product		`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-002	8258132	2027-09-26	U-1743	Drug product		`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-003	8258132	2027-09-26	U-901	Drug product		`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N021549-003	8258132	2027-09-26	U-1743	Drug product		`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	8258132	2027-09-26	U-901	Drug product		`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-002	8258132	2027-09-26	U-1743	Drug product		`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-003	8258132	2027-09-26	U-901	Drug product		`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021549-003	8258132	2027-09-26	U-1743	Drug product		`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	8258132	2027-09-26	U-901	Drug product		`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-002	8258132	2027-09-26	U-1743	Drug product		`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-003	8258132	2027-09-26	U-901	Drug product		`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021549-003	8258132	2027-09-26	U-1743	Drug product		`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	8258132	2027-09-26	U-901	Drug product		`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-002	8258132	2027-09-26	U-1743	Drug product		`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-003	8258132	2027-09-26	U-901	Drug product		`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021549-003	8258132	2027-09-26	U-1743	Drug product		`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	8258132	2027-09-26	U-901	Drug product		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-002	8258132	2027-09-26	U-1743	Drug product		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-003	8258132	2027-09-26	U-901	Drug product		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021549-003	8258132	2027-09-26	U-1743	Drug product		`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	8258132	2027-09-26	U-901	Drug product		`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-002	8258132	2027-09-26	U-1743	Drug product		`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-003	8258132	2027-09-26	U-901	Drug product		`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021549-003	8258132	2027-09-26	U-1743	Drug product		`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	8258132	2027-09-26	U-1743	Drug product	2012-09-27	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-001	8258132	2027-09-26	U-901	Drug product	2012-09-27	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	8258132	2027-09-26	U-901	Drug product		`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021549-002	8258132	2027-09-26	U-1743	Drug product		`03ed91905a0d…`

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
2abc3e32-ae1f-4dec-be1c-0c39ac95b38e	Product name	7	20240514
5d352eda-d4de-4572-9a3f-32d6fd204f9a	Product name	1	20230911
3a5d67cc-4a03-45a3-8d74-5aeb67631be4	Product name	1	20230831
85fc66a9-58b2-e194-7cdb-89ff44dcf3e6	Product name	4	20210518
9f9a82fd-fcee-442f-9233-7f2d2f9f4568	Product name	1	20180108

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
42254-160-01	2019-09-24	C162847	48780-1	9350213a-3e06-c013-e053-90daa90a1393	These highlights do not include all the information needed to use EMEND safely and effectively. See full prescribing information for EMEND. EMEND (aprepitant) Capsules Initial U.S. Approval: 2003

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
42254-160-01	EMEND	1 in 1 CARTON	CAPSULE	1		1
42254-160-01	EMEND	1 in 1 BLISTER PACK	CAPSULE	1		1

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
42254-160-01	EA - Each	42254-160	27a6be70-da09-4fea-bb5c-efa3ce06221c	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
aprepitant	ACTIVE INGREDIENT	1NF15YR6UY	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
aprepitant	ACTIVE MOIETY	1NF15YR6UY	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
CELLULOSE, MICROCRYSTALLINE	INACTIVE INGREDIENT	OP1R32D61U	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
FERRIC OXIDE YELLOW	INACTIVE INGREDIENT	EX438O2MRT	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
gelatin	INACTIVE INGREDIENT	2G86QN327L	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
hydroxypropyl cellulose	INACTIVE INGREDIENT	RFW2ET671P	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
silicon dioxide	INACTIVE INGREDIENT	ETJ7Z6XBU4	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
sucrose	INACTIVE INGREDIENT	C151H8M554	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1
titanium dioxide	INACTIVE INGREDIENT	15FIX9V2JP	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
42254-160	EMEND (APREPITANT) CAPSULE [REBEL DISTRIBUTORS CORP]	1	Legacy NDC, 2 package rows	20120420_ec44482e-6194-4829-a3f7-ebe8d48a41a5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
EMEND	APREPITANT	Merck Sharp & Dohme LLC	696f9e80-9cae-403b-de9e-078343ce4713	2024-07-05	Warnings, Adverse reactions	Exact identifier application applno (NDA): 021549 application number: NDA021549

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
1NF15YR6UY	APREPITANT	170729-80-3	APREPITANT

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
644088	aprepitant 40 MG Oral Capsule	PSN	ec44482e-6194-4829-a3f7-ebe8d48a41a5	1
644278	Emend 40 MG Oral Capsule	PSN	ec44482e-6194-4829-a3f7-ebe8d48a41a5	1
644278	aprepitant 40 MG Oral Capsule [Emend]	SBD	ec44482e-6194-4829-a3f7-ebe8d48a41a5	1
644088	aprepitant 40 MG Oral Capsule	SCD	ec44482e-6194-4829-a3f7-ebe8d48a41a5	1
644278	Emend 40 MG Oral Capsule	SY	ec44482e-6194-4829-a3f7-ebe8d48a41a5	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Status
42254-160-01	42254016001	1 in 1 CARTON	Historical