Femara

Product NDC
0078-0249
11-digit product format
000780249
Labeler code
0078
Product ID
0078-0249_f052c25a-d848-4b2d-8ff3-73bee0c89ad7
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
letrozole
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Novartis Pharmaceuticals Corporation
Application
NDA020726
Marketing category
NDA
Marketing start
1997-07-31
Substance
LETROZOLE
Active strength
2.5 mg/1
Pharmacologic classes
Aromatase Inhibitor [EPC], Aromatase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020726-001FEMARALETROZOLE2.5MGTABLET / ORALABRLD, RS1997-07-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N020726-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-2587673890dc5c…
2021-03-12 10:30 UTC2021-03N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-253f01610625f2…
2019-09-15 20:21 UTC2019-09N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25b00525d2431f…
2019-07-19 19:46 UTC2019-07N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-253f0d92c62455…
2023-05-13 08:27 UTC2023-05N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25053a50430f4f…
2023-01-26 05:58 UTC2023-01N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020726-001FEMARA2.5MGTABLET / ORALABRLD, RS1997-07-25e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N020726-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020726-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020726-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020726-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020726-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020726-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020726-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020726-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020726-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020726-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020726-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020726-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020726-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020726-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020726-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020726-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020726-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020726-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020726-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020726-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020726-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020726-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03N020726-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020726-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020726-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020726-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09N020726-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07N020726-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020726-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020726-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020726-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020726-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020726-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020726-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020726-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N020726-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N020726-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020726-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020726-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020726-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Femara
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LETROZOLE2.5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7LKK855W8IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
153124Internal RxNorm lookup
200064Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
82b77d74-085f-45ac-a7dd-1f5c038bf406Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d50ad188-a2a9-1aec-5d6c-f8612e9e5867Product name420190528
4f1e9b6f-5fe1-47c9-ab31-3c39ee923083Product name220170713

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0078-0249-15Femara30 in 1 BOTTLE, PLASTICTABLET, FILM COATED3031

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0078-0249-15EA - Each0078-0249caa3e001-9ec4-457d-b930-5163d06ba6ea12012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
LETROZOLEACTIVE INGREDIENT7LKK855W8IFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
LETROZOLEACTIVE MOIETY7LKK855W8IFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
FERRIC OXIDE REDINACTIVE INGREDIENT1K09F3G675FEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
LACTOSE MONOHYDRATEINACTIVE INGREDIENTEWQ57Q8I5XFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30FEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1AFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4FEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
SODIUM STARCH GLYCOLATE TYPE A POTATOINACTIVE INGREDIENT5856J3G2A2FEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
STARCH, CORNINACTIVE INGREDIENTO8232NY3SJFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
TALCINACTIVE INGREDIENT7SEV7J4R1UFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPFEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]16
LETROZOLEACTIVE INGREDIENT7LKK855W8IFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
LETROZOLEACTIVE MOIETY7LKK855W8IFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
FERRIC OXIDE REDINACTIVE INGREDIENT1K09F3G675FEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
LACTOSE MONOHYDRATEINACTIVE INGREDIENTEWQ57Q8I5XFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30FEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1AFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4FEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
SODIUM STARCH GLYCOLATE TYPE A POTATOINACTIVE INGREDIENT5856J3G2A2FEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
STARCH, CORNINACTIVE INGREDIENTO8232NY3SJFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
TALCINACTIVE INGREDIENT7SEV7J4R1UFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPFEMARA (LETROZOLE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0078-0249FEMARA (LETROZOLE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION]29Current NDC, Legacy NDC, 1 package rows20241222_82b77d74-085f-45ac-a7dd-1f5c038bf406.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
FemaraLETROZOLENovartis Pharmaceuticals Corporation82b77d74-085f-45ac-a7dd-1f5c038bf4062026-06-11Warnings, Adverse reactionsExact identifier
application applno (NDA): 020726
application number: NDA020726
ndc (product): 0078-0249

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
153124Femara 2.5 MG Oral TabletPSN82b77d74-085f-45ac-a7dd-1f5c038bf40631
200064letrozole 2.5 MG Oral TabletPSN82b77d74-085f-45ac-a7dd-1f5c038bf40631
153124letrozole 2.5 MG Oral Tablet [Femara]SBD82b77d74-085f-45ac-a7dd-1f5c038bf40631
200064letrozole 2.5 MG Oral TabletSCD82b77d74-085f-45ac-a7dd-1f5c038bf40631
153124Femara 2.5 MG Oral TabletSY82b77d74-085f-45ac-a7dd-1f5c038bf40631
153124Femara 2.5 MG Oral TabletPSNe11b0a54-92bd-4790-8b80-f439f7093c012
200064letrozole 2.5 MG Oral TabletPSNe11b0a54-92bd-4790-8b80-f439f7093c012
153124letrozole 2.5 MG Oral Tablet [Femara]SBDe11b0a54-92bd-4790-8b80-f439f7093c012
200064letrozole 2.5 MG Oral TabletSCDe11b0a54-92bd-4790-8b80-f439f7093c012
153124Femara 2.5 MG Oral TabletSYe11b0a54-92bd-4790-8b80-f439f7093c012

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0078-0249-150007802491530 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0078-0249-15) 1997-07-310000-00-00NoNoCurrent