LETROZOLE

Product NDC
51991-759
11-digit product format
519910759
Labeler code
51991
Product ID
51991-759_35b275df-f687-4e29-828b-637d5377cc73
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
LETROZOLE
Dosage form
TABLET
Route
ORAL
Labeler
Breckenridge Pharmaceutical, Inc.
Application
ANDA200161
Marketing category
ANDA
Marketing start
2011-06-04
Substance
LETROZOLE
Active strength
2.5 mg/1
Pharmacologic classes
Aromatase Inhibitor [EPC], Aromatase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A200161-001LETROZOLELETROZOLE2.5MGTABLET / ORALAB2011-06-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A200161-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-032680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-031e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-038072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-034b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0387673890dc5c…
2021-03-12 10:30 UTC2021-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-038869cabd3fbd…
2020-11-12 02:37 UTC2020-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03c0c555d07b60…
2019-12-14 00:12 UTC2019-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033f01610625f2…
2019-09-15 20:21 UTC2019-09A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03b00525d2431f…
2019-07-19 19:46 UTC2019-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-036a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-031c564ffb4f44…
2023-12-20 04:57 UTC2023-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-039b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033f0d92c62455…
2023-05-13 08:27 UTC2023-05A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03053a50430f4f…
2023-01-26 05:58 UTC2023-01A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A200161-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A200161-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200161-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A200161-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200161-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200161-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200161-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200161-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200161-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200161-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200161-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200161-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200161-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200161-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200161-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200161-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200161-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200161-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200161-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200161-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200161-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A200161-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A200161-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A200161-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A200161-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A200161-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A200161-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A200161-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A200161-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A200161-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A200161-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A200161-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A200161-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A200161-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A200161-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A200161-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A200161-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A200161-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A200161-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A200161-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
LETROZOLE
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LETROZOLE2.5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7LKK855W8IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
200064Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
63e54b62-a30d-4a56-9215-75e7a0b0bf02Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d50ad188-a2a9-1aec-5d6c-f8612e9e5867Product name420190528
4f1e9b6f-5fe1-47c9-ab31-3c39ee923083Product name220170713

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
51991-759-10LETROZOLE1000 in 1 BOTTLETABLET100011
51991-759-33LETROZOLE30 in 1 BOTTLETABLET3011
51991-759-90LETROZOLE90 in 1 BOTTLETABLET9011

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
51991-759-10EA - Each51991-75992be9c9c-0f1a-4436-81e8-e952e697e07112012-07-24
51991-759-33EA - Each51991-759589924c7-2265-4455-9e0b-dc1a5deb127a12012-07-24
51991-759-90EA - Each51991-759facf04f1-9588-4989-8e4e-be896505323912023-01-09

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
LETROZOLEACTIVE INGREDIENT7LKK855W8ILETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
LETROZOLEACTIVE MOIETY7LKK855W8ILETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61ULETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
FERRIC OXIDE YELLOWINACTIVE INGREDIENTEX438O2MRTLETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
HYPROMELLOSE 2910 (6 MPA.S)INACTIVE INGREDIENT0WZ8WG20P6LETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
LACTOSE MONOHYDRATEINACTIVE INGREDIENTEWQ57Q8I5XLETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30LETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
POLYETHYLENE GLYCOL 8000INACTIVE INGREDIENTQ662QK8M3BLETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4LETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
SODIUM STARCH GLYCOLATE TYPE A POTATOINACTIVE INGREDIENT5856J3G2A2LETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
STARCH, CORNINACTIVE INGREDIENTO8232NY3SJLETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
TALCINACTIVE INGREDIENT7SEV7J4R1ULETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPLETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
51991-759LETROZOLE TABLET [BRECKENRIDGE PHARMACEUTICAL, INC.]11Current NDC, Legacy NDC, 3 package rows20240327_63e54b62-a30d-4a56-9215-75e7a0b0bf02.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LETROZOLELETROZOLEBreckenridge Pharmaceutical, Inc.63e54b62-a30d-4a56-9215-75e7a0b0bf022026-07-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
ndc (product): 51991-759
LETROZOLELETROZOLEA-S Medication Solutions3baa3912-3e64-473b-8ec6-8557aa7907c22026-06-26Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
LETROZOLELETROZOLEAvPAK93f317f1-96d1-498e-e053-2995a90ac60d2026-01-20Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
LETROZOLELETROZOLEBryant Ranch Prepack3cc750a5-cc88-4b42-b4ab-a87e760f291d2024-05-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
LetrozoleLETROZOLENatco Pharma Limited35c73219-c39e-4e10-b944-76009b061e792020-11-05Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
200064letrozole 2.5 MG Oral TabletPSN63e54b62-a30d-4a56-9215-75e7a0b0bf0211
200064letrozole 2.5 MG Oral TabletSCD63e54b62-a30d-4a56-9215-75e7a0b0bf0211
200064letrozole 2.5 MG Oral TabletPSN3cc750a5-cc88-4b42-b4ab-a87e760f291d8
200064letrozole 2.5 MG Oral TabletSCD3cc750a5-cc88-4b42-b4ab-a87e760f291d8
200064letrozole 2.5 MG Oral TabletPSN93f317f1-96d1-498e-e053-2995a90ac60d5
200064letrozole 2.5 MG Oral TabletSCD93f317f1-96d1-498e-e053-2995a90ac60d5

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
51991-759-10519910759101000 TABLET in 1 BOTTLE (51991-759-10) 1000 tablet2011-06-040000-00-00NoNoCurrent
51991-759-335199107593330 TABLET in 1 BOTTLE (51991-759-33) 30 tablet2011-06-040000-00-00NoNoCurrent
51991-759-905199107599090 TABLET in 1 BOTTLE (51991-759-90) 90 tablet2022-10-010000-00-00NoNoCurrent