Sacubitril and Valsartan

Product NDC
42385-930
11-digit product format
423850930
Labeler code
42385
Product ID
42385-930_b47b5c7e-1c20-429c-9560-07f5f06cdce3
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Sacubitril and Valsartan
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Laurus Labs Limited
Application
ANDA213676
Marketing category
ANDA
Marketing start
2024-11-11
Substance
SACUBITRIL; VALSARTAN
Active strength
24; 26 mg/1; mg/1
Pharmacologic classes
Angiotensin 2 Receptor Antagonists [MoA], Angiotensin 2 Receptor Blocker [EPC], Neprilysin Inhibitor [EPC], Neprilysin Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A213676-001SACUBITRIL AND VALSARTANSACUBITRIL; VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28
A213676-002SACUBITRIL AND VALSARTANSACUBITRIL; VALSARTAN49MG;51MGTABLET / ORALAB2024-05-28
A213676-003SACUBITRIL AND VALSARTANSACUBITRIL; VALSARTAN97MG;103MGTABLET / ORALAB2024-05-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A213676-001AB
A213676-002AB
A213676-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-28d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28d06236e962d9…
2024-10-29 15:01 UTC2024-10A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-28d06236e962d9…
2024-10-29 15:01 UTC2024-10A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-2879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-2879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-28301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-281e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213676-002SACUBITRIL AND VALSARTAN49MG;51MGTABLET / ORALAB2024-05-281e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213676-003SACUBITRIL AND VALSARTAN97MG;103MGTABLET / ORALAB2024-05-281e350fbaab3a…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A213676-001SACUBITRIL AND VALSARTAN24MG;26MGTABLET / ORALAB2024-05-28a50c72e98297…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A213676-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213676-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213676-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213676-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213676-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213676-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A213676-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213676-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213676-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213676-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213676-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213676-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213676-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213676-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213676-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213676-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213676-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213676-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213676-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213676-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213676-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213676-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213676-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213676-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213676-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213676-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213676-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213676-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A213676-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A213676-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213676-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213676-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213676-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213676-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213676-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213676-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213676-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213676-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213676-003AB11e350fbaab3a…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A213676-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Sacubitril and Valsartan
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SACUBITRIL24 mg/1
VALSARTAN26 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
17ERJ0MKGIInternal UNII lookup
80M03YXJ7IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1656340Internal RxNorm lookup
1656349Internal RxNorm lookup
1656354Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
b47b5c7e-1c20-429c-9560-07f5f06cdce3Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
692a3434-fece-49c6-9b7d-ed7aefc52b50Product name320260317
b15e9aa6-d523-ca97-480e-570e0543a342Product name420251024
265792b3-b999-c010-7364-a7db20b9d4d9Product name520250515
e7dfdaab-7cf9-4f89-804c-eff5108d94d1Product name920250305
b6abae2f-ee27-47bc-b150-54dc8d969483Product name220250221
52311e76-a520-4bd2-9d5b-e0b6d6f44519Product name220231208
a8e65197-7914-7acf-c7ec-914d53819b34Product name320190624
f5231d08-c52b-a5a0-ba93-675895c292beProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42385-930-10Sacubitril and Valsartan10 in 1 BLISTER PACKTABLET, FILM COATED101
42385-930-17Sacubitril and Valsartan10 in 1 BLISTER PACKTABLET, FILM COATED101
42385-930-18Sacubitril and Valsartan180 in 1 BOTTLETABLET, FILM COATED1801
42385-930-30Sacubitril and Valsartan30 in 1 BOTTLETABLET, FILM COATED301
42385-930-60Sacubitril and Valsartan60 in 1 BOTTLETABLET, FILM COATED601
42385-930-68Sacubitril and Valsartan100 in 1 CARTONTABLET, FILM COATED1001
42385-930-72Sacubitril and Valsartan100 in 1 CARTONTABLET, FILM COATED1001

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
42385-930SACUBITRIL AND VALSARTAN TABLET, FILM COATED [LAURUS LABS LIMITED]1Current NDC, 7 package rows20241112_b47b5c7e-1c20-429c-9560-07f5f06cdce3.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Sacubitril and ValsartanSACUBITRIL AND VALSARTANANI Pharmaceuticals, Inc.a1fa7066-8ab4-47e3-a701-6c5170700d112026-05-27Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213676
application number: ANDA213676
Sacubitril and ValsartanSACUBITRIL AND VALSARTANLaurus Labs Limitedb47b5c7e-1c20-429c-9560-07f5f06cdce32024-11-07Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213676
application number: ANDA213676
ndc (product): 42385-930

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1656340sacubitril 24 MG / valsartan 26 MG Oral TabletPSNb47b5c7e-1c20-429c-9560-07f5f06cdce31
1656349sacubitril 49 MG / valsartan 51 MG Oral TabletPSNb47b5c7e-1c20-429c-9560-07f5f06cdce31
1656354sacubitril 97 MG / valsartan 103 MG Oral TabletPSNb47b5c7e-1c20-429c-9560-07f5f06cdce31
1656340sacubitril 24 MG / valsartan 26 MG Oral TabletSCDb47b5c7e-1c20-429c-9560-07f5f06cdce31
1656349sacubitril 49 MG / valsartan 51 MG Oral TabletSCDb47b5c7e-1c20-429c-9560-07f5f06cdce31
1656354sacubitril 97 MG / valsartan 103 MG Oral TabletSCDb47b5c7e-1c20-429c-9560-07f5f06cdce31

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
42385-930-104238509301010 in 1 BLISTER PACKHistorical
42385-930-174238509301710 in 1 BLISTER PACKHistorical
42385-930-1842385093018180 TABLET, FILM COATED in 1 BOTTLE (42385-930-18) 2024-11-11NoNoCurrent
42385-930-304238509303030 TABLET, FILM COATED in 1 BOTTLE (42385-930-30) 2024-11-11NoNoCurrent
42385-930-604238509306060 TABLET, FILM COATED in 1 BOTTLE (42385-930-60) 2024-11-11NoNoCurrent
42385-930-6842385093068100 BLISTER PACK in 1 CARTON (42385-930-68) / 10 TABLET, FILM COATED in 1 BLISTER PACK (42385-930-10) 100 blister pack2024-11-11NoNoCurrent
42385-930-7242385093072100 BLISTER PACK in 1 CARTON (42385-930-72) / 10 TABLET, FILM COATED in 1 BLISTER PACK (42385-930-17) 100 blister pack2024-11-11NoNoCurrent