Adapalene

Product NDC
72657-158
Requested package NDC
72657-158-15
11-digit product format
726570158
Labeler code
72657
Product ID
72657-158_52ea6426-f743-4a3f-b927-5940f4428593
Type
HUMAN OTC DRUG
Nonproprietary name
Adapalene
Dosage form
GEL
Route
TOPICAL
Labeler
GLENMARK THERAPEUTICS INC., USA
Application
ANDA091314
Marketing category
ANDA
Marketing start
2023-03-10
Substance
ADAPALENE
Active strength
1 mg/g
Pharmacologic classes
Retinoid [EPC], Retinoids [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A091314-001ADAPALENEADAPALENE0.1%GEL / TOPICAL2010-07-01

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 44 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-018072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-015c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-015d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-014b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A091314-001ADAPALENE0.1%GEL / TOPICALAB2010-07-0174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A091314-002ADAPALENE0.1%GEL / TOPICAL2019-07-0974a2ff9319b5…
2022-03-09 01:35 UTC2022-03A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-0187673890dc5c…
2021-03-12 10:30 UTC2021-03A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-015aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-018869cabd3fbd…
2020-11-12 02:37 UTC2020-11A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01c0c555d07b60…
2019-12-14 00:12 UTC2019-12A091314-001ADAPALENE0.1%GEL / TOPICALAB2010-07-013f01610625f2…
2019-12-14 00:12 UTC2019-12A091314-002ADAPALENE0.1%GEL / TOPICAL2019-07-093f01610625f2…
2019-09-15 20:21 UTC2019-09A091314-001ADAPALENE0.1%GEL / TOPICALAB2010-07-01b00525d2431f…
2019-09-15 20:21 UTC2019-09A091314-002ADAPALENE0.1%GEL / TOPICAL2019-07-09b00525d2431f…
2019-07-19 19:46 UTC2019-07A091314-001ADAPALENE0.1%GEL / TOPICALAB2010-07-01ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-016a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-011c564ffb4f44…
2023-12-20 04:57 UTC2023-12A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-019b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-013f0d92c62455…
2023-05-13 08:27 UTC2023-05A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-01053a50430f4f…
2023-01-26 05:58 UTC2023-01A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-013bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A091314-001ADAPALENE0.1%GEL / TOPICAL2010-07-013a93d1ddd44b…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2019-12-13 00:20 UTC2019-12A091314-001AB174a2ff9319b5…
2019-12-14 00:12 UTC2019-12A091314-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A091314-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A091314-001AB1ea99ee380514…

Additional Listing Data#

Finished product
Yes
Brand name base
Adapalene
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ADAPALENE1 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1L4806J2QFInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
307731Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
42c1c354-2c00-4bc2-bbd3-a5dd5ff9a208Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a46239a7-5963-4008-8cbb-6b9000f497ebProduct name120250721
d9d61457-6a5a-41fc-b418-e5479a2904b7Product name220230303
91d0a1ed-5d14-5017-c7aa-3602ee038695Product name320210111
3f45980c-c196-47e5-0e5e-48b7c57327c5Product name520200428
5c3dfd42-8936-4261-a420-cfcbbf3030aaProduct name220161206
08f39758-2d46-8afe-73ca-39fe69052a2bProduct name120140508
8ae7bcde-1dd2-b073-852b-f464987f7427Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72657-158-17Adapalene15 g in 1 TUBEGEL155
72657-158-17Adapalene1 in 1 CARTONGEL15
72657-158-55Adapalene45 g in 1 TUBEGEL455
72657-158-55Adapalene1 in 1 CARTONGEL15
72657-158-15Adapalene15 g in 1 BOTTLE, PUMPGEL151
72657-158-15Adapalene1 in 1 CARTONGEL11
72657-158-45Adapalene1 in 1 CARTONGEL11
72657-158-45Adapalene45 g in 1 BOTTLE, PUMPGEL451

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
72657-158-17GM - Gram72657-158ffe8760d-71af-40ef-adc8-b4bd2b03ca6d12025-12-16
72657-158-55GM - Gram72657-1588e8bd92d-776e-4c94-a3bc-7fa6007dc63112025-12-16

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72657-158ADAPALENE GEL [GLENMARK THERAPEUTICS INC., USA]4Current NDC, 4 package rows20240726_42c1c354-2c00-4bc2-bbd3-a5dd5ff9a208.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 15 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AdapaleneADAPALENETOP CARE (Topco Associates LLC)07351ab9-ed46-4ef8-85f3-bb6cc7af17c32026-05-19WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENEYYBA Corp47d3a5f5-410c-288f-e063-6294a90a0d922026-02-03WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENEGLENMARK THERAPEUTICS INC., USA42c1c354-2c00-4bc2-bbd3-a5dd5ff9a2082026-01-31WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
ndc (product): 72657-158
AdapaleneADAPALENEGLENMARK THERAPEUTICS INC., USAec6811f7-4728-41b1-8647-d63bb135e24e2026-01-31WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
ndc (package): 72657-158-15
ndc (product): 72657-158
ndc11 (package): 72657015815
Curist Acne ReliefADAPALENELittle Pharma, Inc.e6380880-5299-0826-e053-2a95a90a19422026-01-11WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
EffaclarADAPALENELOreal USA Products Ince94854c5-6bb8-43db-b898-4d47a419d0752025-12-23WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENEWalgreens53087d52-3fef-4d28-b2ef-93470e3e19b52025-12-11WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENEDolgencorp, Inc. (DOLLAR GENERAL & REXALL)62fab99a-f91b-4f0f-9143-9c9bc69df7592025-08-25WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENECVS Pharmacy7fb758ce-4f15-4130-8612-9113a764b5cd2025-08-25WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPLANE 0.1%Acne Free, LLC0dc574e0-397a-7bc8-e063-6394a90a27e22025-07-24WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
Adapalene GelADAPLAENEAcne Free LLC0ce4684a-4733-e669-e063-6394a90a58c12025-07-24WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENEMEIJER, INC.74715ce7-351f-495b-8637-57d8098156812023-07-10WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENEP & L Development, LLCa57b4381-03ee-4b4d-b607-9e266f80f7732022-12-12WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
AdapaleneADAPALENELOreal USA Products Inc24e0fd2f-05dc-4ff4-838f-ee022a3a9c202019-11-25WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314
EffaclarADAPALENELOreal USA Products Inca47b204a-3815-4a2b-9a7d-2c2b65b837bb2019-08-23WarningsExact identifier
application applno (ANDA): 091314
application number: ANDA091314

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
307731adapalene 0.1 % Topical GelPSN42c1c354-2c00-4bc2-bbd3-a5dd5ff9a2085
307731adapalene 0.001 MG/MG Topical GelSCD42c1c354-2c00-4bc2-bbd3-a5dd5ff9a2085
307731adapalene 0.1 % Topical GelSY42c1c354-2c00-4bc2-bbd3-a5dd5ff9a2085
307731adapalene 0.1 % Topical GelPSNec6811f7-4728-41b1-8647-d63bb135e24e1
307731adapalene 0.001 MG/MG Topical GelSCDec6811f7-4728-41b1-8647-d63bb135e24e1
307731adapalene 0.1 % Topical GelSYec6811f7-4728-41b1-8647-d63bb135e24e1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
72657-158-15726570158151 BOTTLE, PUMP in 1 CARTON (72657-158-15) / 15 g in 1 BOTTLE, PUMP2025-03-14NoNoCurrent