FDA.reportPublic FDA data

diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]

RxCUI
1248356
RxNorm name
diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]
Display name
ZZZQUIL (Oral Liquid)
Full name
diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]
Term type
SBD
Status
Active
Strength
50 mg/30ml
Dose form
Sol
Route
Oral Liquid
Updated
2026-07-25 06:55:11

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
042012
Active start
042012
Multiple ingredient
NO
Branded
YES

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
diphenhydramine hydrochloride1.67 MG / 1 MLdiphenhydraminediphenhydramine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Oral Solution316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
diphenhydramine3498

Source Vocabulary Codes#

Code type, Value, Category table
Code typeValueCategory
PRESCRIBABLEYATTRIBUTES
RXNAV_STRZzzquil 1.67 MG/ML Oral SolutionNAMES
RxNorm Namediphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]NAMES
RxNorm SynonymZzzquil 1.67 MG/ML Oral SolutionNAMES
RxNorm SynonymZzzquil 50 MG per 30 ML Oral SolutionNAMES
TTYSBDATTRIBUTES
SPL_SET_ID01906eed-78ee-f2a1-e063-6294a90a809bCODES
SPL_SET_ID1be2f00b-5bdd-82e7-e063-6394a90ab9a5CODES
SPL_SET_ID1d608c94-1651-f318-e063-6294a90aa11eCODES
SPL_SET_IDe441c952-cd48-4159-ada2-271ca7541600CODES
RxCUI1248356CODES
MMSL_CODEBD28147CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
37000-500-0137000-500ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing CompanyM010
37000-500-0637000-500ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing CompanyM010
37000-500-0837000-500ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing CompanyM010
37000-500-1237000-500ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing CompanyM010
37000-500-2437000-500ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing CompanyM010
37000-500-3637000-500ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing CompanyM010
69423-795-1269423-795VICKS ZzzQuil Diphenhydramine HydrochlorideThe Procter & Gamble Manufacturing CompanyM010
84126-316-0484126-316ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing CompanyM010

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M01037000-500ZzzQuil DIPHENHYDRAMINE HYDROCHLORIDEOTC MONOGRAPH DRUGThe Procter & Gamble Manufacturing Company

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 27 matching rows.

NDC11, Source, Active table
NDC11SourceActive
23900001396rxnav_ndcsyes
23900001398rxnav_ndcsyes
23900001531rxnav_ndcsyes
23900001619rxnav_ndcsyes
23900003855rxnav_ndcsyes
23900003856rxnav_ndcsyes
23900003858rxnav_ndcsyes
23900003859rxnav_ndcsyes
37000043012rxnav_ndcsyes
37000043106rxnav_ndcsyes
37000043112rxnav_ndcsyes
37000043124rxnav_ndcsyes
37000050001rxnav_ndcsyes
37000050006rxnav_ndcsyes
37000050008rxnav_ndcsyes
37000050012rxnav_ndcsyes
37000050024rxnav_ndcsyes
37000050036rxnav_ndcsyes
69423079512rxnav_ndcsyes
84126031604rxnav_ndcsyes
37000043024rxnav_historical
37000050004rxnav_historical
37000093006rxnav_historical
37000093012rxnav_historical
37000093024rxnav_historical
69423096512rxnav_historical
69423097904rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Vicks ZzzQuil Nighttime Sleep-AidDIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing Company1be2f00b-5bdd-82e7-e063-6394a90ab9a52026-04-06WarningsExact identifier
ndc (package): 37000-500-12
ndc (package): 37000-500-24
ndc11 (package): 37000050012
ndc11 (package): 37000050024
rxcui: 1248356
ZzzQuil Nighttime Sleep-AidDIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing Company1d608c94-1651-f318-e063-6294a90aa11e2026-03-05WarningsExact identifier
ndc (package): 84126-316-04
ndc (product): 84126-316
ndc11 (package): 84126031604
rxcui: 1248356
ZzzQuil Nighttime Sleep-AidDIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing Companye441c952-cd48-4159-ada2-271ca75416002026-02-20WarningsExact identifier
ndc (package): 37000-500-06
ndc (package): 37000-500-36
ndc (package): 37000-500-08
ndc (package): 37000-500-12
ndc (package): 37000-500-24
ndc (package): 37000-500-01
ndc (product): 37000-500
ndc11 (package): 37000050036
ndc11 (package): 37000050001
ndc11 (package): 37000050006
ndc11 (package): 37000050008
ndc11 (package): 37000050012
ndc11 (package): 37000050024
rxcui: 1248356
VICKS ZzzQuil NIGHTTIME SLEEP-AID Diphenhydramine HCl FREE OFDIPHENHYDRAMINE HYDROCHLORIDEThe Procter & Gamble Manufacturing Company01906eed-78ee-f2a1-e063-6294a90a809b2025-10-03WarningsExact identifier
ndc (package): 69423-795-12
ndc (product): 69423-795
ndc11 (package): 69423079512
rxcui: 1248356

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set IDRxNorm stringTTYSPL versionLabelEffective
e441c952-cd48-4159-ada2-271ca7541600diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]SBD21ZzzQuil™ NIGHTTIME SLEEP-AID WARMING BERRY20260220
e441c952-cd48-4159-ada2-271ca7541600Zzzquil 1.67 MG/ML Oral SolutionSY21ZzzQuil™ NIGHTTIME SLEEP-AID WARMING BERRY20260220
e441c952-cd48-4159-ada2-271ca7541600ZzzQuil NIGHTTIME SLEEP-AID 50 MG in 30 mL Oral SolutionPSN21ZzzQuil™ NIGHTTIME SLEEP-AID WARMING BERRY20260220
e441c952-cd48-4159-ada2-271ca7541600Zzzquil 50 MG per 30 ML Oral SolutionSY21ZzzQuil™ NIGHTTIME SLEEP-AID WARMING BERRY20260220
dd1ab38a-afe6-07ea-e053-2995a90ad98fdiphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]SBD10ZzzQuil™ NIGHTTIME SLEEP-AID20241010
dd1ab38a-afe6-07ea-e053-2995a90ad98fZzzquil 50 MG per 30 ML Oral SolutionSY10ZzzQuil™ NIGHTTIME SLEEP-AID20241010
dd1ab38a-afe6-07ea-e053-2995a90ad98fZzzquil 1.67 MG/ML Oral SolutionSY10ZzzQuil™ NIGHTTIME SLEEP-AID20241010
dd1ab38a-afe6-07ea-e053-2995a90ad98fZzzQuil NIGHTTIME SLEEP-AID 50 MG in 30 mL Oral SolutionPSN10ZzzQuil™ NIGHTTIME SLEEP-AID20241010
01906eed-78ee-f2a1-e063-6294a90a809bZzzquil 50 MG per 30 ML Oral SolutionSY7Vicks ZzzQuil™ Nighttime Sleep-Aid Diphenhydramine HCl FREE OF20251003
01906eed-78ee-f2a1-e063-6294a90a809bZzzQuil NIGHTTIME SLEEP-AID 50 MG in 30 mL Oral SolutionPSN7Vicks ZzzQuil™ Nighttime Sleep-Aid Diphenhydramine HCl FREE OF20251003
01906eed-78ee-f2a1-e063-6294a90a809bdiphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]SBD7Vicks ZzzQuil™ Nighttime Sleep-Aid Diphenhydramine HCl FREE OF20251003
01906eed-78ee-f2a1-e063-6294a90a809bZzzquil 1.67 MG/ML Oral SolutionSY7Vicks ZzzQuil™ Nighttime Sleep-Aid Diphenhydramine HCl FREE OF20251003
1be2f00b-5bdd-82e7-e063-6394a90ab9a5diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]SBD3Vicks ZzzQuil™ Nighttime Sleep-Aid Warming Berry Liquid WITH ZzzQuil Sleep Nasal Strips CONVENIENCE KIT20260406
1be2f00b-5bdd-82e7-e063-6394a90ab9a5Zzzquil 50 MG per 30 ML Oral SolutionSY3Vicks ZzzQuil™ Nighttime Sleep-Aid Warming Berry Liquid WITH ZzzQuil Sleep Nasal Strips CONVENIENCE KIT20260406
1be2f00b-5bdd-82e7-e063-6394a90ab9a5ZzzQuil NIGHTTIME SLEEP-AID 50 MG in 30 mL Oral SolutionPSN3Vicks ZzzQuil™ Nighttime Sleep-Aid Warming Berry Liquid WITH ZzzQuil Sleep Nasal Strips CONVENIENCE KIT20260406
1be2f00b-5bdd-82e7-e063-6394a90ab9a5Zzzquil 1.67 MG/ML Oral SolutionSY3Vicks ZzzQuil™ Nighttime Sleep-Aid Warming Berry Liquid WITH ZzzQuil Sleep Nasal Strips CONVENIENCE KIT20260406
1d608c94-1651-f318-e063-6294a90aa11eZzzquil 1.67 MG/ML Oral SolutionSY3ZzzQuil™ NIGHTTIME SLEEP-AID20260305
1d608c94-1651-f318-e063-6294a90aa11eZzzQuil NIGHTTIME SLEEP-AID 50 MG in 30 mL Oral SolutionPSN3ZzzQuil™ NIGHTTIME SLEEP-AID20260305
1d608c94-1651-f318-e063-6294a90aa11eZzzquil 50 MG per 30 ML Oral SolutionSY3ZzzQuil™ NIGHTTIME SLEEP-AID20260305
1d608c94-1651-f318-e063-6294a90aa11ediphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]SBD3ZzzQuil™ NIGHTTIME SLEEP-AID20260305

DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
1be2f00b-5bdd-82e7-e063-6394a90ab9a5Vicks ZzzQuil™ Nighttime Sleep-Aid Warming Berry Liquid WITH ZzzQuil Sleep Nasal Strips CONVENIENCE KITThe Procter & Gamble Manufacturing Company20260406
1d608c94-1651-f318-e063-6294a90aa11eZzzQuil™ NIGHTTIME SLEEP-AIDThe Procter & Gamble Manufacturing Company20260305
e441c952-cd48-4159-ada2-271ca7541600ZzzQuil™ NIGHTTIME SLEEP-AID WARMING BERRYThe Procter & Gamble Manufacturing Company20260220
01906eed-78ee-f2a1-e063-6294a90a809bVicks ZzzQuil™ Nighttime Sleep-Aid Diphenhydramine HCl FREE OFThe Procter & Gamble Manufacturing Company20251003
dd1ab38a-afe6-07ea-e053-2995a90ad98fZzzQuil™ NIGHTTIME SLEEP-AIDThe Procter & Gamble Manufacturing Company20241010
29bf8bed-1efe-4514-9dc9-b7087a1785d8ZzzQuil™ Nighttime Sleep-AidThe Procter & Gamble Manufacturing Company20231018
d2a50e5a-170f-5530-e053-2a95a90a2f16Vicks ZzzQuil™ Nighttime Sleep-Aid Diphenhydramine HCl FREE OFThe Procter & Gamble Manufacturing Company20230728
7b0cc06d-c1bd-415b-953f-6f89adbb2e59ZzzQuil™ Alcohol Free Nighttime Sleep-AidThe Procter & Gamble Manufacturing Company20230209
8dbbef23-8746-935e-e053-2a95a90af25cZzzQuil™ Soothing Berry FlavorThe Procter & Gamble Manufacturing Company20220729
7c7ff596-24c8-4894-a0c7-9df5bfc3aec6National Council for Prescription Drug Programs20130303

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCR06AAAminoalkyl ethersATC1-4diphenhydramine
ATCD04AAAntihistamines for topical useATC1-4diphenhydramine
FDASPLN0000175587Histamine-1 Receptor AntagonistEPChas_epcdiphenhydramine
FDASPLN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine hydrochloride
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007774LactationDISEASEci_withdiphenhydramine
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine hydrochloride
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine hydrochloride
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH1.67 MG/ML
ATTRIBUTESGENERAL_CARDINALITYSINGLE
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESPRESCRIBABLEY
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
ATTRIBUTESTTYSBD
CODESMMSL_CODEBD28147
CODESRxCUI1248356
CODESSPL_SET_ID01906eed-78ee-f2a1-e063-6294a90a809b
CODESSPL_SET_ID1be2f00b-5bdd-82e7-e063-6394a90ab9a5
CODESSPL_SET_ID1d608c94-1651-f318-e063-6294a90aa11e
CODESSPL_SET_IDe441c952-cd48-4159-ada2-271ca7541600
NAMESPrescribable SynonymZzzQuil NIGHTTIME SLEEP-AID 50 MG in 30 mL Oral Solution
NAMESRXNAV_STRZzzquil 1.67 MG/ML Oral Solution
NAMESRxNorm Namediphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]
NAMESRxNorm SynonymZzzquil 1.67 MG/ML Oral Solution
NAMESRxNorm SynonymZzzquil 50 MG per 30 ML Oral Solution
NAMESTallman SynonymdiphenhydrAMINE hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK
SOURCESSourceMultum MediSource Lexicon