aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet

RxCUI
1536498
RxNorm name
aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
Display name
Aspirin/Dextromethorphan/Phenylephrine (Effervescent)
Full name
aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
Term type
SCD
Status
Active
Strength
325-10-7.8 mg
Dose form
Tab
Route
Effervescent
Updated
2026-09-14 22:57:59

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
062014
Active start
062014
Multiple ingredient
YES
Branded
NO

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
aspirin325 MG / 1 EACHaspirinaspirin
dextromethorphan hydrobromide10 MG / 1 EACHdextromethorphandextromethorphan hydrobromide
phenylephrine bitartrate7.8 MG / 1 EACHphenylephrinephenylephrine bitartrate

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Effervescent Oral Tablet1535727

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
aspirin1191
dextromethorphan3289
phenylephrine8163

Source Vocabulary Codes#

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
0280-0024-010280-0024Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy asprin, dextromethorphan hydrobromide, phenylephrine bitartrateBayer HealthCare LLC.M012
0280-0024-020280-0024Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy asprin, dextromethorphan hydrobromide, phenylephrine bitartrateBayer HealthCare LLC.M012
71992-154-2071992-154ALKA SELTZER PLUS Cold Day and Night Effervescent ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATESincronia Logistica, S.A. de C.V.M012

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M0120280-0024Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy asprin, dextromethorphan hydrobromide, phenylephrine bitartrateOTC MONOGRAPH DRUGBayer HealthCare LLC.

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 4 matching rows.

NDC11, Source, Active table
NDC11SourceActive
00280002401rxnav_ndcsyes
00280002402rxnav_ndcsyes
71992015420rxnav_ndcsyes
00280141032rxnav_historical_indirect

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 8 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ALKA SELTZER COLD Cold Congestion Severe Day Night Fast DissolveASPIRIN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATEBayer HealthCare LLC.50738a43-7299-270c-e063-6294a90af2cc2026-04-27WarningsExact identifier
rxcui: 1536498
Alka-Seltzer Plus Severe Cold PowerFast Fizz Non DrowsyASPRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATEBayer HealthCare LLC.a355d987-77ce-9e32-e053-2995a90a64312026-01-08WarningsExact identifier
ndc (package): 0280-0024-01
ndc (package): 0280-0024-02
ndc (product): 0280-0024
ndc11 (package): 00280002402
ndc11 (package): 00280002401
rxcui: 1536498
Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and NightASPIRIN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATEBayer HealthCare LLC.fc60af2f-83cb-99ea-e053-6394a90a0b3b2026-01-08WarningsExact identifier
rxcui: 1536498
Alka-Seltzer Plus Severe Cold PowerFast FizzASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE, DOXYLAMINE SUCCINATEBayer HealthCare LLC.a37c9d9d-52db-23ff-e053-2995a90a8f762025-12-04WarningsExact identifier
rxcui: 1536498
Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and NightASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATEBayer HealthCare LLC.c2232241-6e57-1427-e053-2995a90a488a2025-12-04WarningsExact identifier
rxcui: 1536498
Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and NightASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATEBayer HealthCare LLC.d7711cd6-5058-548d-e053-2a95a90ac54d2025-12-04WarningsExact identifier
rxcui: 1536498
Alka-Seltzer Plus Cold Day and NightASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE, DOXYLAMINE SUCCINATEBayer HealthCare LLC.75894849-a0ba-57be-e053-2a91aa0a049a2025-12-04WarningsExact identifier
rxcui: 1536498
ALKA SELTZER PLUS Cold Day and Night EffervescentASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATESincronia Logistica, S.A. de C.V.c478df69-823a-4112-8f44-323249a9f38f2023-10-23WarningsExact identifier
ndc (package): 71992-154-20
ndc (product): 71992-154
ndc11 (package): 71992015420
rxcui: 1536498

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 8 matching rows.

Set ID, RxNorm mappings, Terms table
Set IDRxNorm mappingsTermsSPL versionLabelEffective
fc60af2f-83cb-99ea-e053-6394a90a0b3baspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]313Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614460 & 161445920260108
d7711cd6-5058-548d-e053-2a95a90ac54daspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]38Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614460 & 16189720251204
75894849-a0ba-57be-e053-2a91aa0a049aaspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]36Alka-Seltzer Plus® Cold Day & Night Effervescent Tablets20251204
a355d987-77ce-9e32-e053-2995a90a6431aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]35Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Effervescent Tablets UI161446020260108
c2232241-6e57-1427-e053-2995a90a488aaspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]35Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614460 & 16189720251204
a37c9d9d-52db-23ff-e053-2995a90a8f76aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]34Alksa-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614458 & 161446020251204
c478df69-823a-4112-8f44-323249a9f38faspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]34ALKA-SELTZER PLUS Cold Day & Night Effervescent20231023
50738a43-7299-270c-e063-6294a90af2ccaspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY]31ALKA SELTZER COLD Cold Congestion Severe Day Night Fast Dissolve Tablets UI 1614460 & 161445920260427

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
a355d987-77ce-9e32-e053-2995a90a6431Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Effervescent Tablets UI1614460Bayer HealthCare LLC.20260108
a355d987-77ce-9e32-e053-2995a90a6431Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Effervescent Tablets UI1614460Bayer HealthCare LLC.20231211
c478df69-823a-4112-8f44-323249a9f38fALKA-SELTZER PLUS Cold Day & Night EffervescentSincronia Logistica, S.A. de C.V.20231023

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCC01CAAdrenergic and dopaminergic agentsATC1-4phenylephrine
ATCR05DAOpium alkaloids and derivativesATC1-4dextromethorphan
ATCA01ADOther agents for local oral treatmentATC1-4aspirin
ATCC05AXOther agents for treatment of hemorrhoids and anal fissures for topical useATC1-4phenylephrine
ATCB01ACPlatelet aggregation inhibitors excl. heparinATC1-4aspirin
ATCN02BASalicylic acid and derivativesATC1-4aspirin
ATCR01BASympathomimeticsATC1-4phenylephrine
ATCS01FBSympathomimetics excl. antiglaucoma preparationsATC1-4phenylephrine
ATCS01GASympathomimetics used as decongestantsATC1-4phenylephrine
ATCR01ABSympathomimetics, combinations excl. corticosteroidsATC1-4phenylephrine
ATCR01AASympathomimetics, plainATC1-4phenylephrine
FDASPLN0000186105alpha-1 Adrenergic AgonistEPChas_epcphenylephrine
FDASPLN0000175722Nonsteroidal Anti-inflammatory DrugEPChas_epcaspirin
FDASPLN0000175578Platelet Aggregation InhibitorEPChas_epcaspirin
FDASPLN0000182149Sigma-1 AgonistEPChas_epcdextromethorphan
FDASPLN0000181821Uncompetitive N-methyl-D-aspartate Receptor AntagonistEPChas_epcdextromethorphan
FDASPLN0000182147Sigma-1 Receptor AgonistsMOAhas_moadextromethorphan
FDASPLN0000181819Uncompetitive NMDA Receptor AntagonistsMOAhas_moadextromethorphan
MEDRTD001241AspirinCHEMhas_ingredientaspirin
MEDRTD003915DextromethorphanCHEMhas_ingredientdextromethorphan
MEDRTD003915DextromethorphanCHEMhas_ingredientdextromethorphan hydrobromide
MEDRTD010656PhenylephrineCHEMhas_ingredientphenylephrine
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine bitartrate
MEDRTD001172Arthritis, RheumatoidDISEASEmay_treataspirin
MEDRTD001778Blood Coagulation DisordersDISEASEci_withaspirin
MEDRTD001791Blood Platelet DisordersDISEASEci_withaspirin
MEDRTD002544Cerebral InfarctionDISEASEmay_preventaspirin
MEDRTD002644ChickenpoxDISEASEci_withaspirin
MEDRTD002675Child, PreschoolDISEASEci_withaspirin
MEDRTD003371CoughDISEASEmay_treatdextromethorphan
MEDRTD003371CoughDISEASEmay_preventdextromethorphan
MEDRTD003371CoughDISEASEmay_treatdextromethorphan hydrobromide
MEDRTD003371CoughDISEASEmay_preventdextromethorphan hydrobromide
MEDRTD004342Drug HypersensitivityDISEASEci_withdextromethorphan hydrobromide
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine
MEDRTD004342Drug HypersensitivityDISEASEci_withaspirin
MEDRTD004342Drug HypersensitivityDISEASEci_withdextromethorphan
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine bitartrate
MEDRTD005334FeverDISEASEmay_treataspirin
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine bitartrate
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine bitartrate
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine
MEDRTD006073GoutDISEASEmay_treataspirin
MEDRTD006396HematemesisDISEASEci_withaspirin
MEDRTD006474Hemorrhagic DisordersDISEASEci_withaspirin
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine bitartrate
MEDRTD006973HypertensionDISEASEci_withphenylephrine bitartrate
MEDRTD006973HypertensionDISEASEci_withphenylephrine
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine bitartrate
MEDRTD007223InfantDISEASEci_withaspirin
MEDRTD007249InflammationDISEASEmay_treataspirin
MEDRTD002546Ischemic Attack, TransientDISEASEmay_preventaspirin
MEDRTD008551MelenaDISEASEci_withaspirin
MEDRTD015878MydriasisDISEASEinducesphenylephrine
MEDRTD015878MydriasisDISEASEinducesphenylephrine bitartrate
MEDRTD009203Myocardial InfarctionDISEASEmay_preventaspirin
MEDRTD009298Nasal PolypsDISEASEci_withaspirin
MEDRTD010003OsteoarthritisDISEASEmay_treataspirin
MEDRTD010146PainDISEASEmay_preventaspirin
MEDRTD010146PainDISEASEmay_treataspirin
MEDRTD011225Pre-EclampsiaDISEASEmay_preventaspirin
MEDRTD011263Pregnancy Trimester, ThirdDISEASEci_withaspirin
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine bitartrate
MEDRTD012213Rheumatic FeverDISEASEmay_treataspirin
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine bitartrate
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine bitartrate
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine bitartrate
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine bitartrate
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine bitartrate
MEDRTN0000000160Cyclooxygenase InhibitorsMOAhas_moaaspirin
MEDRTN0000000184Monoamine Oxidase InhibitorsMOAci_moadextromethorphan
MEDRTN0000000184Monoamine Oxidase InhibitorsMOAci_moadextromethorphan hydrobromide
MEDRTN0000000109Serotonin Uptake InhibitorsMOAhas_moadextromethorphan hydrobromide
MEDRTN0000000109Serotonin Uptake InhibitorsMOAhas_moadextromethorphan
MEDRTN0000182147Sigma-1 Receptor AgonistsMOAhas_moadextromethorphan hydrobromide
MEDRTN0000182147Sigma-1 Receptor AgonistsMOAhas_moadextromethorphan
MEDRTN0000181819Uncompetitive NMDA Receptor AntagonistsMOAhas_moadextromethorphan hydrobromide
MEDRTN0000181819Uncompetitive NMDA Receptor AntagonistsMOAhas_moadextromethorphan
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine bitartrate
MEDRTN0000008701Decreased Medullary Respiratory DrivePEhas_pedextromethorphan
MEDRTN0000008701Decreased Medullary Respiratory DrivePEhas_pedextromethorphan hydrobromide
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine bitartrate
MEDRTN0000008831Decreased Platelet Activating Factor ProductionPEhas_peaspirin
MEDRTN0000008832Decreased Platelet AggregationPEhas_peaspirin
MEDRTN0000008836Decreased Prostaglandin ProductionPEhas_peaspirin
MEDRTN0000009006Decreased Thromboxane ProductionPEhas_peaspirin
MEDRTN0000000026Hepatic MetabolismPKhas_pkaspirin
MEDRTN0000000042Renal ExcretionPKhas_pkaspirin

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH325 MG / 10 MG / 7.8 MG
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESRXNAV_HUMAN_DRUGUS
NAMESPrescribable Synonymaspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK