aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
- RxCUI
- 1536498
- RxNorm name
- aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
- Display name
- Aspirin/Dextromethorphan/Phenylephrine (Effervescent)
- Full name
- aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
- Term type
- SCD
- Status
- Active
- Strength
- 325-10-7.8 mg
- Dose form
- Tab
- Route
- Effervescent
- Updated
- 2026-09-14 22:57:59
RxNorm Status History#
- Status
- Active
- Source
- RXNORM
- Current
- YES
- Release start
- 062014
- Active start
- 062014
- Multiple ingredient
- YES
- Branded
- NO
Ingredients And Strength#
| Ingredient | Strength | Base | Basis of strength |
|---|---|---|---|
| aspirin | 325 MG / 1 EACH | aspirin | aspirin |
| dextromethorphan hydrobromide | 10 MG / 1 EACH | dextromethorphan | dextromethorphan hydrobromide |
| phenylephrine bitartrate | 7.8 MG / 1 EACH | phenylephrine | phenylephrine bitartrate |
Dose Form Concepts#
| Dose form | RxCUI |
|---|---|
| Effervescent Oral Tablet | 1535727 |
Derived Ingredient Concepts#
| Ingredient | RxCUI |
|---|---|
| aspirin | 1191 |
| dextromethorphan | 3289 |
| phenylephrine | 8163 |
Source Vocabulary Codes#
| Code type | Values | Count | Category |
|---|---|---|---|
| PRESCRIBABLE | Y | 1 | ATTRIBUTES |
| RXNAV_STR | aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet | 1 | NAMES |
| RxNorm Name | aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet | 1 | NAMES |
| RxNorm Synonym | ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet | 1 | NAMES |
| TTY | SCD | 1 | ATTRIBUTES |
| SPL_SET_ID | 8 linked values | 8 | CODES |
| RxCUI | 1536498 | 1 | CODES |
FDA NDC Products And Packages#
| Package NDC | Product NDC | Name | Labeler | Application |
|---|---|---|---|---|
| 0280-0024-01 | 0280-0024 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy asprin, dextromethorphan hydrobromide, phenylephrine bitartrate | Bayer HealthCare LLC. | M012 |
| 0280-0024-02 | 0280-0024 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy asprin, dextromethorphan hydrobromide, phenylephrine bitartrate | Bayer HealthCare LLC. | M012 |
| 71992-154-20 | 71992-154 | ALKA SELTZER PLUS Cold Day and Night Effervescent ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE | Sincronia Logistica, S.A. de C.V. | M012 |
Drugs@FDA Applications#
UNII Substances#
No records found.
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| ALKA SELTZER COLD Cold Congestion Severe Day Night Fast Dissolve | ASPIRIN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE | Bayer HealthCare LLC. | 50738a43-7299-270c-e063-6294a90af2cc | 2026-04-27 | Warnings | 1536498 |
| Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy | ASPRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE | Bayer HealthCare LLC. | a355d987-77ce-9e32-e053-2995a90a6431 | 2026-01-08 | Warnings | 0280-0024-01 0280-0024-02 0280-0024 00280002402 00280002401 1536498 |
| Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night | ASPIRIN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE | Bayer HealthCare LLC. | fc60af2f-83cb-99ea-e053-6394a90a0b3b | 2026-01-08 | Warnings | 1536498 |
| Alka-Seltzer Plus Severe Cold PowerFast Fizz | ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE, DOXYLAMINE SUCCINATE | Bayer HealthCare LLC. | a37c9d9d-52db-23ff-e053-2995a90a8f76 | 2025-12-04 | Warnings | 1536498 |
| Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night | ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE | Bayer HealthCare LLC. | c2232241-6e57-1427-e053-2995a90a488a | 2025-12-04 | Warnings | 1536498 |
| Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night | ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE | Bayer HealthCare LLC. | d7711cd6-5058-548d-e053-2a95a90ac54d | 2025-12-04 | Warnings | 1536498 |
| Alka-Seltzer Plus Cold Day and Night | ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE, DOXYLAMINE SUCCINATE | Bayer HealthCare LLC. | 75894849-a0ba-57be-e053-2a91aa0a049a | 2025-12-04 | Warnings | 1536498 |
| ALKA SELTZER PLUS Cold Day and Night Effervescent | ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE | Sincronia Logistica, S.A. de C.V. | c478df69-823a-4112-8f44-323249a9f38f | 2023-10-23 | Warnings | 71992-154-20 71992-154 71992015420 1536498 |
DailyMed RxNorm Mappings#
| Set ID | RxNorm mappings | Terms | SPL version | Label | Effective |
|---|---|---|---|---|---|
| fc60af2f-83cb-99ea-e053-6394a90a0b3b | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 13 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614460 & 1614459 | 20260108 |
| d7711cd6-5058-548d-e053-2a95a90ac54d | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 8 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614460 & 161897 | 20251204 |
| 75894849-a0ba-57be-e053-2a91aa0a049a | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 6 | Alka-Seltzer Plus® Cold Day & Night Effervescent Tablets | 20251204 |
| a355d987-77ce-9e32-e053-2995a90a6431 | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 5 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Effervescent Tablets UI1614460 | 20260108 |
| c2232241-6e57-1427-e053-2995a90a488a | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 5 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614460 & 161897 | 20251204 |
| a37c9d9d-52db-23ff-e053-2995a90a8f76 | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 4 | Alksa-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Effervescent Tablets UI 1614458 & 1614460 | 20251204 |
| c478df69-823a-4112-8f44-323249a9f38f | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 4 | ALKA-SELTZER PLUS Cold Day & Night Effervescent | 20231023 |
| 50738a43-7299-270c-e063-6294a90af2cc | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SCD] · ASA 325 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet [SY] | 3 | 1 | ALKA SELTZER COLD Cold Congestion Severe Day Night Fast Dissolve Tablets UI 1614460 & 1614459 | 20260427 |
Recently Linked DailyMed Labels#
| Set ID | Title | Manufacturer | Effective |
|---|---|---|---|
| a355d987-77ce-9e32-e053-2995a90a6431 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Effervescent Tablets UI1614460 | Bayer HealthCare LLC. | 20260108 |
| a355d987-77ce-9e32-e053-2995a90a6431 | Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Effervescent Tablets UI1614460 | Bayer HealthCare LLC. | 20231211 |
| c478df69-823a-4112-8f44-323249a9f38f | ALKA-SELTZER PLUS Cold Day & Night Effervescent | Sincronia Logistica, S.A. de C.V. | 20231023 |
Drug Classes#
| Source | Class ID | Class | Type | Relationship | Drug concept |
|---|---|---|---|---|---|
| ATC | C01CA | Adrenergic and dopaminergic agents | ATC1-4 | phenylephrine | |
| ATC | R05DA | Opium alkaloids and derivatives | ATC1-4 | dextromethorphan | |
| ATC | A01AD | Other agents for local oral treatment | ATC1-4 | aspirin | |
| ATC | C05AX | Other agents for treatment of hemorrhoids and anal fissures for topical use | ATC1-4 | phenylephrine | |
| ATC | B01AC | Platelet aggregation inhibitors excl. heparin | ATC1-4 | aspirin | |
| ATC | N02BA | Salicylic acid and derivatives | ATC1-4 | aspirin | |
| ATC | R01BA | Sympathomimetics | ATC1-4 | phenylephrine | |
| ATC | S01FB | Sympathomimetics excl. antiglaucoma preparations | ATC1-4 | phenylephrine | |
| ATC | S01GA | Sympathomimetics used as decongestants | ATC1-4 | phenylephrine | |
| ATC | R01AB | Sympathomimetics, combinations excl. corticosteroids | ATC1-4 | phenylephrine | |
| ATC | R01AA | Sympathomimetics, plain | ATC1-4 | phenylephrine | |
| FDASPL | N0000186105 | alpha-1 Adrenergic Agonist | EPC | has_epc | phenylephrine |
| FDASPL | N0000175722 | Nonsteroidal Anti-inflammatory Drug | EPC | has_epc | aspirin |
| FDASPL | N0000175578 | Platelet Aggregation Inhibitor | EPC | has_epc | aspirin |
| FDASPL | N0000182149 | Sigma-1 Agonist | EPC | has_epc | dextromethorphan |
| FDASPL | N0000181821 | Uncompetitive N-methyl-D-aspartate Receptor Antagonist | EPC | has_epc | dextromethorphan |
| FDASPL | N0000182147 | Sigma-1 Receptor Agonists | MOA | has_moa | dextromethorphan |
| FDASPL | N0000181819 | Uncompetitive NMDA Receptor Antagonists | MOA | has_moa | dextromethorphan |
| MEDRT | D001241 | Aspirin | CHEM | has_ingredient | aspirin |
| MEDRT | D003915 | Dextromethorphan | CHEM | has_ingredient | dextromethorphan |
| MEDRT | D003915 | Dextromethorphan | CHEM | has_ingredient | dextromethorphan hydrobromide |
| MEDRT | D010656 | Phenylephrine | CHEM | has_ingredient | phenylephrine |
| MEDRT | D013447 | Sulfites | CHEM | ci_chemclass | phenylephrine |
| MEDRT | D013447 | Sulfites | CHEM | ci_chemclass | phenylephrine bitartrate |
| MEDRT | D001172 | Arthritis, Rheumatoid | DISEASE | may_treat | aspirin |
| MEDRT | D001778 | Blood Coagulation Disorders | DISEASE | ci_with | aspirin |
| MEDRT | D001791 | Blood Platelet Disorders | DISEASE | ci_with | aspirin |
| MEDRT | D002544 | Cerebral Infarction | DISEASE | may_prevent | aspirin |
| MEDRT | D002644 | Chickenpox | DISEASE | ci_with | aspirin |
| MEDRT | D002675 | Child, Preschool | DISEASE | ci_with | aspirin |
| MEDRT | D003371 | Cough | DISEASE | may_treat | dextromethorphan |
| MEDRT | D003371 | Cough | DISEASE | may_prevent | dextromethorphan |
| MEDRT | D003371 | Cough | DISEASE | may_treat | dextromethorphan hydrobromide |
| MEDRT | D003371 | Cough | DISEASE | may_prevent | dextromethorphan hydrobromide |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | dextromethorphan hydrobromide |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | phenylephrine |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | aspirin |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | dextromethorphan |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | phenylephrine bitartrate |
| MEDRT | D005334 | Fever | DISEASE | may_treat | aspirin |
| MEDRT | D005401 | Fissure in Ano | DISEASE | may_treat | phenylephrine |
| MEDRT | D005401 | Fissure in Ano | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D005902 | Glaucoma, Open-Angle | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D005902 | Glaucoma, Open-Angle | DISEASE | may_treat | phenylephrine |
| MEDRT | D006073 | Gout | DISEASE | may_treat | aspirin |
| MEDRT | D006396 | Hematemesis | DISEASE | ci_with | aspirin |
| MEDRT | D006474 | Hemorrhagic Disorders | DISEASE | ci_with | aspirin |
| MEDRT | D006484 | Hemorrhoids | DISEASE | may_treat | phenylephrine |
| MEDRT | D006484 | Hemorrhoids | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D006973 | Hypertension | DISEASE | ci_with | phenylephrine bitartrate |
| MEDRT | D006973 | Hypertension | DISEASE | ci_with | phenylephrine |
| MEDRT | D007022 | Hypotension | DISEASE | may_treat | phenylephrine |
| MEDRT | D007022 | Hypotension | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D007223 | Infant | DISEASE | ci_with | aspirin |
| MEDRT | D007249 | Inflammation | DISEASE | may_treat | aspirin |
| MEDRT | D002546 | Ischemic Attack, Transient | DISEASE | may_prevent | aspirin |
| MEDRT | D008551 | Melena | DISEASE | ci_with | aspirin |
| MEDRT | D015878 | Mydriasis | DISEASE | induces | phenylephrine |
| MEDRT | D015878 | Mydriasis | DISEASE | induces | phenylephrine bitartrate |
| MEDRT | D009203 | Myocardial Infarction | DISEASE | may_prevent | aspirin |
| MEDRT | D009298 | Nasal Polyps | DISEASE | ci_with | aspirin |
| MEDRT | D010003 | Osteoarthritis | DISEASE | may_treat | aspirin |
| MEDRT | D010146 | Pain | DISEASE | may_prevent | aspirin |
| MEDRT | D010146 | Pain | DISEASE | may_treat | aspirin |
| MEDRT | D011225 | Pre-Eclampsia | DISEASE | may_prevent | aspirin |
| MEDRT | D011263 | Pregnancy Trimester, Third | DISEASE | ci_with | aspirin |
| MEDRT | D011538 | Pruritus Ani | DISEASE | may_treat | phenylephrine |
| MEDRT | D011538 | Pruritus Ani | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D012213 | Rheumatic Fever | DISEASE | may_treat | aspirin |
| MEDRT | D012223 | Rhinitis, Vasomotor | DISEASE | may_treat | phenylephrine |
| MEDRT | D012223 | Rhinitis, Vasomotor | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D012772 | Shock, Septic | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D012772 | Shock, Septic | DISEASE | may_treat | phenylephrine |
| MEDRT | D013617 | Tachycardia, Supraventricular | DISEASE | may_treat | phenylephrine |
| MEDRT | D013617 | Tachycardia, Supraventricular | DISEASE | may_treat | phenylephrine bitartrate |
| MEDRT | D017180 | Tachycardia, Ventricular | DISEASE | ci_with | phenylephrine bitartrate |
| MEDRT | D017180 | Tachycardia, Ventricular | DISEASE | ci_with | phenylephrine |
| MEDRT | N0000000209 | Adrenergic alpha-Agonists | MOA | has_moa | phenylephrine |
| MEDRT | N0000000209 | Adrenergic alpha-Agonists | MOA | has_moa | phenylephrine bitartrate |
| MEDRT | N0000000160 | Cyclooxygenase Inhibitors | MOA | has_moa | aspirin |
| MEDRT | N0000000184 | Monoamine Oxidase Inhibitors | MOA | ci_moa | dextromethorphan |
| MEDRT | N0000000184 | Monoamine Oxidase Inhibitors | MOA | ci_moa | dextromethorphan hydrobromide |
| MEDRT | N0000000109 | Serotonin Uptake Inhibitors | MOA | has_moa | dextromethorphan hydrobromide |
| MEDRT | N0000000109 | Serotonin Uptake Inhibitors | MOA | has_moa | dextromethorphan |
| MEDRT | N0000182147 | Sigma-1 Receptor Agonists | MOA | has_moa | dextromethorphan hydrobromide |
| MEDRT | N0000182147 | Sigma-1 Receptor Agonists | MOA | has_moa | dextromethorphan |
| MEDRT | N0000181819 | Uncompetitive NMDA Receptor Antagonists | MOA | has_moa | dextromethorphan hydrobromide |
| MEDRT | N0000181819 | Uncompetitive NMDA Receptor Antagonists | MOA | has_moa | dextromethorphan |
| MEDRT | N0000008371 | Conjunctival Arterial Vasoconstriction | PE | has_pe | phenylephrine |
| MEDRT | N0000008371 | Conjunctival Arterial Vasoconstriction | PE | has_pe | phenylephrine bitartrate |
| MEDRT | N0000008701 | Decreased Medullary Respiratory Drive | PE | has_pe | dextromethorphan |
| MEDRT | N0000008701 | Decreased Medullary Respiratory Drive | PE | has_pe | dextromethorphan hydrobromide |
| MEDRT | N0000008896 | Decreased Nasal and Sinus Secretions | PE | has_pe | phenylephrine |
| MEDRT | N0000008896 | Decreased Nasal and Sinus Secretions | PE | has_pe | phenylephrine bitartrate |
| MEDRT | N0000008831 | Decreased Platelet Activating Factor Production | PE | has_pe | aspirin |
| MEDRT | N0000008832 | Decreased Platelet Aggregation | PE | has_pe | aspirin |
| MEDRT | N0000008836 | Decreased Prostaglandin Production | PE | has_pe | aspirin |
| MEDRT | N0000009006 | Decreased Thromboxane Production | PE | has_pe | aspirin |
| MEDRT | N0000000026 | Hepatic Metabolism | PK | has_pk | aspirin |
| MEDRT | N0000000042 | Renal Excretion | PK | has_pk | aspirin |
Properties#
| Category | Property | Value |
|---|---|---|
| ATTRIBUTES | AVAILABLE_STRENGTH | 325 MG / 10 MG / 7.8 MG |
| ATTRIBUTES | GENERAL_CARDINALITY | MULTI |
| ATTRIBUTES | HUMAN_DRUG | US |
| ATTRIBUTES | RXNAV_HUMAN_DRUG | US |
| NAMES | Prescribable Synonym | aspirin 325 MG / dextromethorphan HBr 10 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet |
| SOURCES | Source | Metathesaurus FDA Structured Product Labels |
| SOURCES | Source | Micromedex RED BOOK |