| Estradiol Tablets, USP | REMEDYREPACK INC. | 20260601 | 11 |
| These highlights do not include all the information needed to use ESTRADIOL AND NORETHINDRONE ACETATE TABLETS safely and effectively. See full prescribing information for ESTRADIOL AND NORETHINDRONE ACETATE TABLETS. ESTRADIOL and NORETHINDRONE ACETATE tablets, for oral use Initial U.S. Approval: 1998 | Ingenus Pharmaceuticals, LLC | Novast Laboratories, Ltd. | 20260529 | 5 |
| These highlights do not include all the information needed to use ESTROGEL safely and effectively. See full prescribing information for ESTROGEL. EstroGel ® 0.06% (estradiol gel) for topical use Initial U.S. Approval: 1975 | ASCEND Therapeutics US, LLC | DPT Laboratories, Ltd. | 20260529 | 55 |
| Estradiol Tablets, USP | A-S Medication Solutions | 20260527 | 3 |
| Estradiol Tablets, USP | REMEDYREPACK INC. | 20260526 | 4 |
| These highlights do not include all the information needed to use ESTRADIOL GEL 0.1% safely and effectively. See full prescribing information for ESTRADIOL GEL 0.1%. E STRADIOL GEL, for topical use Initial U.S. Approval: 1975 | Xiromed, LLC | Chemo Research, S.L. | Laboratorios Leon Farma | 20260518 | 10 |
| DELESTROGEN ® (estradiol valerate injection, USP) | Par Health USA, LLC | 20260513 | 29 |
| HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel, for topical use Initial U.S. Approval: 1975 | Encube Ethicals, Inc. | Encube Ethicals Private Limited | 20260513 | 3 |
| These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel, for topical use Initial U.S. Approval: 1975 | Encube Ethicals, Inc. | Encube Ethicals Private Limited | 20260429 | 5 |
| These highlights do not include all the information needed to use BIJUVA safely and effectively. See full prescribing information for BIJUVA. BIJUVA ® (estradiol and progesterone) capsules, for oral use Initial U.S. Approval: 2018 | Mayne Pharma | Catalent Pharma Solutions, LLC | Sharp Packaging Services, LLC | 20260424 | 6 |
| ESTRING ® (estradiol vaginal system) | Pfizer Laboratories Div Pfizer Inc | Pfizer Inc | 20260423 | 7 |
| These highlights do not include all the information needed to use BIJUVA safely and effectively. See full prescribing information for BIJUVA. BIJUVA ® (estradiol and progesterone) capsules, for oral use Initial U.S. Approval: 2018 | Mayne Pharma LLC | Catalent Pharma Solutions LLC | 20260416 | 13 |
| Estradiol Tablets, USP Rx only | Preferred Pharmaceuticals, Inc. | 20260413 | 3 |
| ESTRADIOL VAGINAL CREAM USP, 0.01% | A-S Medication Solutions | 20260413 | 3 |
| ESTRADIOL VAGINAL CREAM USP, 0.01% | Bryant Ranch Prepack | 20260331 | 105 |
| These highlights do not include all the information needed to use CLIMARA PRO safely and effectively. See full prescribing information for CLIMARA PRO. Climara Pro ® (estradiol/levonorgestrel transdermal system) Initial U.S. Approval: 1975 | Bayer HealthCare Pharmaceuticals Inc. | Kindeva Drug Delivery L.P. | Sixarp, LLC | 20260326 | 27 |
| These highlights do not include all the information needed to use CLIMARA safely and effectively. See full prescribing information for CLIMARA. Climara® (estradiol transdermal system) Initial U.S. Approval: 1975 | Bayer HealthCare Pharmaceuticals Inc. | Kindeva Drug Delivery L.P. | Sixarp, LLC | 20260326 | 25 |
| These highlights do not include all the information needed to use MENOSTAR safely and effectively. See full prescribing information for MENOSTAR. Menostar ® (estradiol transdermal system) Initial U.S. Approval: 1975 | Bayer HealthCare Pharmaceuticals Inc. | 20260312 | 20 |
| These highlights do not include all the information needed to use the ESTRADIOL TRANSDERMAL SYSTEM safely and effectively. See full prescribing information for ESTRADIOL TRANSDERMAL SYSTEM. Estradiol Transdermal System Initial U.S. Approval: 1975 | Sandoz Inc | Bayer HealthCare Pharmaceuticals Inc. | 20260304 | 10 |
| These highlights do not include all the information needed to use ANGELIQ safely and effectively. See full prescribing information for ANGELIQ. ANGELIQ (drospirenone and estradiol) tablets, for oral use Initial U.S. Approval: 2005 | Bayer HealthCare Pharmaceuticals Inc. | 20260302 | 20 |
| These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel, for topical use Initial U.S. Approval: 1975 | Padagis Israel Pharmaceuticals Ltd | 20260228 | 25 |
| These highlights do not include all the information needed to use DIVIGEL safely and effectively. See full prescribing information for DIVIGEL. DIVIGEL ® (estradiol gel), for topical use Initial U.S. Approval: 1975 | Vertical Pharmaceuticals, LLC | 20260227 | 31 |
| These highlights do not include all the information needed to use Estradiol Gel safely and effectively. See full prescribing information for Estradiol Gel. Estradiol Gel, for topical use Initial U.S. Approval: 1975 | Trigen Laboratories, LLC | 20260227 | 8 |
| These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel, for topical use Initial U.S. Approval: 1975 | Amneal Pharmaceuticals NY LLC | Amneal Pharmaceuticals, LLC | 20260219 | 12 |
| 98770987-b313-4f2a-9aac-db0ab2068cc6 | Mylan Pharmaceuticals Inc. | 20260215 | 10 |
| Estradiol Tablets, USP | REMEDYREPACK INC. | 20260213 | 8 |
| These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel, for topical use Initial U.S. Approval: 1975 | Solaris Pharma Corporation | 20260126 | 9 |
| Yuvafem These highlights do not include all the information needed to use YUVAFEM safely and effectively. See full prescribing information for YUVAFEM. YUVAFEM® (estradiol vaginal inserts) Initial U.S. Approval: 1999 | AvKARE | 20260119 | 9 |
| Estradiol Vaginal Cream USP, 0.01% | AvKARE | 20260114 | 5 |
| Estradiol | Direct_Rx | 20260108 | 1 |
| Estradiol Tablets, USP | Northwind Health Company, LLC | 20260101 | 4 |
| Estradiol Tablets, USP | Northwind Health Company, LLC | 20260101 | 4 |
| Estradiol Tablets, USP | Northwind Health Company, LLC | 20260101 | 5 |
| Estradiol Tablets, USP Rx only | Northwind Health Company, LLC | 20260101 | 2 |
| Estradiol Tablets, USP Rx only | Northwind Health Company, LLC | 20260101 | 2 |
| These highlights do not include all the information needed to use ORIAHNN safely and effectively. See full prescribing information for ORIAHNN. ORIAHNN ® (elagolix, estradiol, and norethindrone acetate capsules; elagolix capsules), co-packaged for oral use Initial U.S. Approval: 2020 | AbbVie Inc. | 20251219 | 41 |
| These highlights do not include all the information needed to use FEMRING safely and effectively. See Full Prescribing Information for FEMRING. Femring ® (estradiol acetate vaginal ring) Initial U.S. Approval: 1975 | Millicent US, Inc. | Millicent Pharma (NI) Limited | 20251209 | 7 |
| Estradiol Vaginal Cream USP 0.01% | Teva Pharmaceuticals USA, Inc. | 20251201 | 13 |
| E stradiol Vaginal Cream , USP 0.01% | Alvogen Inc. | 20251125 | 10 |
| 241b605b-607f-483f-8746-1b89b4636e05 | Elanco US Inc. | 20251121 | 9 |
| 75a1b0bc-e602-4494-bc0b-bccbfd3e53d9 | Elanco US Inc. | 20251121 | 10 |
| e392c026-fca9-4d7d-abae-842a7305b191 | Elanco US Inc. | 20251121 | 10 |
| fd1ccdd2-9a4e-4246-ab1f-83fd625c596f | Elanco US Inc. | 20251121 | 10 |
| 84735-014 Estriol cream | Hengyang Chuangjiujia Trading Co., Ltd. | 20251112 | 4 |
| Estradiol Tablets, USP Rx only | NorthStar Rx LLC | ANI Pharmaceuticals, Inc. | 20251111 | 3 |
| ESTRADIOL VALERATE INJECTION, USP RX ONLY | Hikma Pharmaceuticals USA Inc. | 20251110 | 7 |
| These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel, for topical use Initial U.S. Approval: 1975 | ANI Pharmaceuticals, Inc. | Novitium Pharma LLC | 20251104 | 5 |
| ESTRADIOL VAGINAL CREAM USP, 0.01% | Padagis Israel Pharmaceuticals Ltd | 20251031 | 11 |
| Estradiol Tablets, USP Rx only | Bryant Ranch Prepack | 20251028 | 1 |
| These highlights do not include all the information needed to use ESTRADIOL VAGINAL INSERTS safely and effectively. See full prescribing information for ESTRADIOL VAGINAL INSERTS. ESTRADIOL vaginal inserts Initial U.S. Approval: 1999 | Glenmark Pharmaceuticals Inc., USA | Glenmark Pharmaceuticals Limited | 20251028 | 7 |
| ESTRADIOL VAGINAL CREAM USP, 0.01% | Bryant Ranch Prepack | 20251023 | 100 |
| Estradiol Tablets, USP | PD-Rx Pharmaceuticals, Inc. | 20251009 | 8 |
| These highlights do not include all the information needed to use ESTRADIOL VAGINAL INSERTS safely and effectively. See full prescribing information for ESTRADIOL VAGINAL INSERTS. ESTRADIOL vaginal inserts Initial U.S. Approval: 1999 | Aurobindo Pharma Limited | 20250923 | 3 |
| Estradiol Tablets USP | NuCare Pharmaceuticals,Inc. | 20250922 | 2 |
| These highlights do not include all the information needed to use IMVEXXY safely and effectively. See full prescribing information for IMVEXXY. IMVEXXY ® (estradiol vaginal inserts) Initial U.S. Approval: 1975 | Mayne Pharma LLC | Catalent Pharma Solutions LLC | 20250916 | 13 |
| These highlights do not include all the information needed to use MYFEMBREE safely and effectively. See full prescribing information for MYFEMBREE. MYFEMBREE ® (relugolix, estradiol, and norethindrone acetate) tablets, for oral use Initial U.S. Approval: 2021 | Sumitomo Pharma America, Inc | Sumitomo Pharma Switzerland GmbH | 20250904 | 18 |
| These highlights do not include all the information needed to use ESTRADIOL VAGINAL INSERTS safely and effectively. See full prescribing information for ESTRADIOL VAGINAL INSERTS. ESTRADIOL vaginal inserts Initial U.S. Approval: 1999 | NorthStar Rx LLC | Aurobindo Pharma Limited | 20250808 | 1 |
| Estradiol Tablets, USP Rx only | REMEDYREPACK INC. | 20250805 | 5 |
| Estradiol Tablets, USP Rx only | REMEDYREPACK INC. | 20250805 | 5 |
| These highlights do not include all the information needed to use ESTRADIOL TRANSDERMAL SYSTEM CONTINUOUS DELIVERY (ONCE-WEEKLY) safely and effectively. See full prescribing information for ESTRADIOL TRANSDERMAL SYSTEM CONTINUOUS DELIVERY (ONCE-WEEKLY). ESTRADIOL transdermal system continuous delivery (once-weekly) Initial U.S. Approval: 1975 | A-S Medication Solutions | 20250724 | 1 |
| These highlights do not include all the information needed to use ESTRADIOL TRANSDERMAL SYSTEM safely and effectively. See full prescribing information for ESTRADIOL TRANSDERMAL SYSTEM ESTRADIOL TRANSDERMAL SYSTEM Initial U.S. Approval: 1975 | A-S Medication Solutions | 20250724 | 1 |
| Estradiol Vaginal Cream, USP 0.01% | Encube Ethicals, Inc. | Encube Ethicals Private Limited | 20250717 | 1 |
| 386c357d-97ff-8150-e063-6394a90a2ac8 | Nutrition Unlimited INC | 20250705 | 5 |
| ESTRADIOL VALERATE INJECTION, USP Rx Only | Xiromed, LLC | Xiromed Pharma Espana, S.L. | Laboratorios Farmalan, S.A. (Chemo) | 20250703 | 9 |
| These highlights do not include all the information needed to use ESTRADIOL TRANSDERMAL SYSTEM (TWICE-WEEKLY) safely and effectively. See full prescribing information for ESTRADIOL TRANSDERMAL SYSTEM (TWICE-WEEKLY). ESTRADIOL transdermal system (twice-weekly) Initial U.S. Approval: 1975 | Mylan Pharmaceuticals Inc. | 20250623 | 7 |
| These highlights do not include all the information needed to use ESTRADIOL TRANSDERMAL SYSTEM CONTINUOUS DELIVERY (ONCE-WEEKLY) safely and effectively. See full prescribing information for ESTRADIOL TRANSDERMAL SYSTEM CONTINUOUS DELIVERY (ONCE-WEEKLY). ESTRADIOL transdermal system continuous delivery (once-weekly) Initial U.S. Approval: 1975 | Mylan Pharmaceuticals Inc. | 20250623 | 16 |
| Estradiol Tablets, USP Rx only | Coupler LLC | 20250617 | 1 |
| These highlights do not include all the information needed to use ESTRADIOL TRANSDERMAL SYSTEM (TWICE-WEEKLY) safely and effectively. See full prescribing information for ESTRADIOL TRANSDERMAL SYSTEM (TWICE-WEEKLY). ESTRADIOL transdermal system (twice-weekly) Initial U.S. Approval: 1996 | Mylan Pharmaceuticals Inc. | 20250617 | 14 |
| These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel, for topical use Initial U.S. Approval: 1975 | NorthStar Rx LLC | 20250616 | 4 |
| 3.6oz BiEST 2.5 Estrogen Cream | SHYNE BRANDS/BIOLabs PRO | BIOLabs PRO | 20250601 | 1 |
| 3.6oz BiEST 5.0 Estrogen Cream | SHYNE BRANDS/BIOLabs PRO | BIOLabs PRO | 20250601 | 1 |
| Balance Plus Cream | SHYNE BRANDS/BIOLabs PRO | BIOLabs PRO | 20250601 | 1 |
| BiEST 5.0 Estrogen Cream | SHYNE BRANDS | 20250601 | 4 |
| Estradiol Tablets, USP Rx only 8487665/0924F | American Health Packaging | 20250502 | 2 |
| Estradiol Tablets, USP | Preferred Pharmaceuticals Inc. | 20250501 | 8 |
| Estradiol Tablets, USP | A-S Medication Solutions | 20250415 | 31 |
| These highlights do not include all the information needed to use IMVEXXY safely and effectively. See full prescribing information for IMVEXXY. IMVEXXY ® (estradiol vaginal inserts) Initial U.S. Approval: 1975 | Mayne Pharma | Catalent Pharma Solutions, LLC | Sharp Packaging Services, LLC | 20250415 | 5 |
| Estradiol Tablets, USP Rx only | Preferred Pharmaceuticals Inc. | 20250411 | 1 |
| Estradiol Tablets, USP | Bryant Ranch Prepack | 20250328 | 102 |
| Estradiol Tablets, USP | Bryant Ranch Prepack | 20250328 | 9 |
| Estradiol Tablets, USP | Bryant Ranch Prepack | 20250325 | 1021 |
| Estradiol Tablets, USP | PD-Rx Pharmaceuticals, Inc. | 20250313 | 15 |
| Estradiol Tablets USP | NuCare Pharmaceuticals,Inc. | 20250226 | 4 |
| Estradiol Tablets, USP Rx only | PD-Rx Pharmaceuticals, Inc. | 20250220 | 3 |
| Estradiol Tablets, USP | A-S Medication Solutions | 20250218 | 3 |
| ESTRADIOL VAGINAL CREAM USP, 0.01% | NuCare Pharmaceuticals, Inc. | 20250217 | 1 |
| Estradiol Tablets, USP | Asclemed USA, Inc. | ASCLEMED USA INC. DBA ENOVACHEM | 20250213 | 3 |
| These highlights do not include all the information needed to use VAGIFEM safely and effectively. See full prescribing information for VAGIFEM. Vagifem ® (estradiol vaginal inserts) Initial U.S. Approval: 1999 | Novo Nordisk | Novo Nordisk A/S - G8, X9 M.Fl. | 20250210 | 22 |
| Estradiol | Direct_Rx | 20250122 | 3 |
| Estradiol | Direct_Rx | 20250122 | 2 |
| Estradiol Tablets USP | PharmPak, Inc. | 20250116 | 3 |
| These highlights do not include all the information needed to use LOPREEZA safely and effectively. See full prescribing information for LOPREEZA. LOPREEZA ® (estradiol/norethindrone acetate) tablets, for oral use Initial U.S. Approval: 1998 | Amneal Pharmaceuticals NY LLC | Amneal Pharmaceuticals of New York, LLC | 20250116 | 10 |
| Estradiol Tablets, USP | A-S Medication Solutions | 20250109 | 9 |
| Estradiol Vaginal Cream , USP , 0.01% | A-S Medication Solutions | 20250109 | 3 |
| Estradiol Tablets, USP Rx Only | PURACAP LABORATORIES, LLC | EPIC PHARMA, LLC | GRANULATION TECHNOLOGY, INC. | 20250108 | 3 |
| Estradiol Tablets, USP | EPIC PHARMA, LLC | GRANULATION TECHNOLOGY, INC. | 20250107 | 11 |
| Estradiol Tablets, USP Rx only | A-S Medication Solutions | 20241230 | 1 |
| Estradiol Tablets, USP Rx only | A-S Medication Solutions | 20241230 | 1 |
| Estradiol Tablets, USP | A-S Medication Solutions | 20241115 | 1 |
| These highlights do not include all the information needed to use EVAMIST safely and effectively. See full prescribing information for EVAMIST. EVAMIST (estradiol transdermal spray) Initial U.S. Approval: 1975 | Padagis US LLC | 20241029 | 9 |
| These highlights do not include all the information needed to use ESTRADIOL GEL safely and effectively. See full prescribing information for ESTRADIOL GEL. ESTRADIOL gel 0.06%, for topical use Initial U.S. Approval: 1975 | ANI Pharmaceuticals, Inc. | Novitium Pharma LLC | 20241028 | 1 |
| ESTRADIOL VALERATE INJECTION, USP Rx Only | American Regent, Inc. | 20241025 | 5 |
| Estradiol Tablets USP | Proficient Rx LP | 20241001 | 6 |
| Estra-50 & Estra-25 | Advanced Pharmaceutical Technology, Inc. | 20240927 | 11 |
| Estradiol Tablets, USP Rx only | NuCare Pharmaceuticals,Inc. | 20240926 | 1 |
| These highlights do not include all the information needed to use ABIGALE and ABIGALE LO safely and effectively. See full prescribing information for ABIGALE and ABIGALE LO . ABIGALE TM and ABIGALE TM LO (estradiol/norethindrone acetate) tablets, for oral use Initial U.S. Approval: 1998 | Xiromed LLC | 20240917 | 1 |
| Estradiol Tablets, USP Rx only | Bryant Ranch Prepack | 20240903 | 1 |
| E stradiol Vaginal Cream , USP 0.01% | Bryant Ranch Prepack | 20240830 | 106 |
| ESTRACE | A-S Medication Solutions | 20240812 | 20 |
| These highlights do not include all the information needed to use DOTTI safely and effectively. See full prescribing information for DOTTI. DOTTI ® (estradiol transdermal system) Initial U.S. Approval: 1996 | Bryant Ranch Prepack | 20240812 | 102 |
| These highlights do not include all the information needed to use DOTTI safely and effectively. See full prescribing information for DOTTI. DOTTI ® (estradiol transdermal system) Initial U.S. Approval: 1996 | Bryant Ranch Prepack | 20240812 | 102 |
| These highlights do not include all the information needed to use DOTTI safely and effectively. See full prescribing information for DOTTI. DOTTI ® (estradiol transdermal system) Initial U.S. Approval: 1996 | Bryant Ranch Prepack | 20240812 | 102 |
| These highlights do not include all the information needed to use DOTTI safely and effectively. See full prescribing information for DOTTI. DOTTI ® (estradiol transdermal system) Initial U.S. Approval: 1996 | Bryant Ranch Prepack | 20240812 | 102 |
| ESTRADIOL - estradiol cream Teva Pharmaceuticals USA, Inc. E s tr a d iol Vagi n al Cre a m U S P 0.01 % | A-S Medication Solutions | 20240730 | 11 |
| Estradiol Vaginal Cream USP, 0.01% | Bryant Ranch Prepack | 20240726 | 106 |
| Estradiol Tablets, USP | A-S Medication Solutions | 20240718 | 3 |
| Estradiol Tablets USP | NuCare Pharmaceuticals, Inc. | 20240717 | 6 |
| These highlights do not include all the information needed to use DOTTI safely and effectively. See full prescribing information for DOTTI. DOTTI ® (estradiol transdermal system) Initial U.S. Approval: 1996 | Bryant Ranch Prepack | 20240717 | 101 |
| Estradiol Tablets, USP Rx only | Bryant Ranch Prepack | 20240708 | 1 |
| These highlights do not include all the information needed to use ESTRADIOL VAGINAL INSERTS safely and effectively. See full prescribing information for ESTRADIOL VAGINAL INSERTS. ESTRADIOL vaginal inserts Initial U.S. Approval: 1999 | Bryant Ranch Prepack | 20240708 | 103 |